Following a request received from the company, NICE will be undertaking an appraisal of Dabrafenib with trametinib for treating advanced BRAF V600 mutation-positive non-small-cell lung cancer. This was originally terminated guidance TA564. The appraisal is expected to start during April 2022 with a consultation on the draft scope. It is then anticipated that the final scope will be released along with an invitation to participate in the appraisal during mid-June 2022. The deadline for submissions is expected in approximately mid-August 2022.