When NICE first reviewed roflumilast in 2012, limited data meant that it was recommended only if patients were taking it as part of a clinical trial. After two new trials showed the drug eased symptoms that were not being controlled with inhalers, NICE reviewed its guidance and approved roflumilast for eligible patients.
Professor Carole Longson, director of the NICE
Roflumilast is recommended as an option to treat adults with severe COPD whose symptoms continue to worsen despite other treatments. It is a once-a-day tablet that works to reduce irritation and swelling in airways of people with COPD.
Around 122,000 adults in England will be eligible to receive roflumilast.
The draft guidance has been shared with registered organisations who can appeal the decision or highlight factual inaccuracies. If there are no appeals, the final guideline will publish in July and roflumilast will be available on the NHS within three months of that date.