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Disease-specific reference case extension: management of overweight and obesity in adults

  • NICE process and methods
  • Reference number: PMG50
  • Published:  06 May 2026
  • Process
  • History
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  • Overview
  • Introduction
  • 1 Population
  • 2 Intervention and comparators
  • 3 Model structure and health states
  • 4 Clinical parameters
  • 5 Measuring and valuing health effects
  • 6 Cost and healthcare resource use
  • 7 Equality and other considerations
  • Rationale and supporting information
  • Real-world data analysis to inform modelling
  • Methodology
  • Glossary
  • List of appendices (separate documents)
  • References

Overview

This NICE disease-specific reference case extension describes standardised methods for health economic evaluations of interventions for managing overweight and obesity in adults. For further details on developing and implementing disease-specific reference case extensions, see NICE’s position statement on use of disease-specific reference models in economic evaluations.

Last reviewed: 6 May 2026


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