- Recommendation ID
- CG137/5
- Question
AEDs and pregnancy: What is the malformation rate and longer term neurodevelopmental outcome of children born to mothers who have taken AEDs during pregnancy?
- Any explanatory notes
(if applicable) Pregnancy registers are increasing the data that are available on established AEDs; however, these registers may give malformation rates but do not provide controlled long-term data on neurodevelopmental outcome.
The research should include:
-
measures of maternal outcome, including seizure frequency and quality of life
-
major and minor rates of congenital malformations
-
prospective neurodevelopmental (including cognitive) and behavioural outcomes in children born to women and girls with epilepsy (these should be undertaken on a long-term basis and ideally using a cohort study, followed from birth until adult life).
-
Source guidance details
- Comes from guidance
- Epilepsies: diagnosis and management
- Number
- CG137
- Date issued
- January 2012
Other details
| Is this a recommendation for the use of a technology only in the context of research? | No |
| Is it a recommendation that suggests collection of data or the establishment of a register? | No |
| Last Reviewed | 31/10/2019 |