- Recommendation ID
- DG16/1
- Question
- NICE recommends further research to validate the accuracy and precision of the My5-FU assay for the quantitative determination of 5-fluorouracil (5-FU) at the lower end of its measuring range with analytical reference standard methods, including high-performance liquid chromatography and liquid chromatography-mass spectrometry.
- Any explanatory notes
(if applicable) - Studies should investigate the comparability of the methods and determine the clinical significance of discordant results with reference to their impact on subsequent dose adjustments.
Source guidance details
- Comes from guidance
- Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment
- Number
- DG16
- Date issued
- December 2014
Other details
| Is this a recommendation for the use of a technology only in the context of research? | No |
| Is it a recommendation that suggests collection of data or the establishment of a register? | No |
| Last Reviewed | 07/01/2015 |