Recommendation ID
NG124/5
Question

What is the most effective combination of an analgesic with a neuromuscular blocker, or an analgesic with an anaesthetic agent, for premedication in preterm babies requiring elective or semi-elective intubation? 

Any explanatory notes
(if applicable)

There was some evidence from small, single studies that using an analgesic with a neuromuscular blocker, or an anaesthetic such as propofol used alone, is an effective regimen to achieve successful intubation in preterm babies, while avoiding adverse effects.

However, there was a lack of evidence to show exactly which medicines or classes of medicines form the best combination, so the committee recommended that healthcare professionals should consider premedication before elective intubation and recommended that further research be done in this area


Source guidance details

Comes from guidance
Specialist neonatal respiratory care for babies born preterm
Number
NG124
Date issued
April 2019

Other details

Is this a recommendation for the use of a technology only in the context of research? No  
Is it a recommendation that suggests collection of data or the establishment of a register?   No  
Last Reviewed 02/04/2019