PredictSURE IBD and IBDX to guide treatment of Crohn’s disease

Recommendation ID

DG45/01

Question

The committee recommends more research on:

the accuracy of PredictSURE IBD and IBDX tests in identifying people at high or low risk of following a severe course of Crohn's disease
how PredictSURE IBD and IBDX tests, when used alongside clinical features, affect clinical decisions about whether step-up or top-down treatment is offered
the clinical outcomes and costs resulting from a top-down treatment strategy compared with a step-up treatment strategy
how PredictSURE IBD and IBDX tests affect clinical outcomes once someone has been assigned to top-down or step-up treatment, considering the different pathways that children and adults may follow.

Any explanatory notes (if applicable)

Source guidance details

Comes from guidance: PredictSURE IBD and IBDX to guide treatment of Crohn’s disease
Number: DG45
Date issued: February 2022

Is this a recommendation for the use of a technology only in the context of research?	No
Is it a recommendation that suggests collection of data or the establishment of a register?	No
Last Reviewed	28/02/2022