Updating results

Workplace health: long-term sickness absence and capability to work (NG146)

This guideline covers how to help people return to work after long-term sickness absence, reduce recurring sickness absence, and help prevent people moving from short-term to long-term sickness absence.

NICE guideline Published November 2019

Thyroid disease: assessment and management (NG145)

This guideline covers investigating all suspected thyroid disease and managing primary thyroid disease (related to the thyroid rather than the pituitary gland). It does not cover managing thyroid cancer or thyroid disease in pregnancy. It aims to improve quality of life by making recommendations on diagnosis, treatment, long-term care and support.

NICE guideline Published November 2019

Fluocinolone acetonide intravitreal implant for treating chronic diabetic macular oedema in phakic eyes after an inadequate response to previous therapy (TA613)

Evidence-based recommendations on fluocinolone acetonide intravitreal implant (Iluvien) for chronic diabetic macular oedema that has inadequately responded to

Technology appraisal guidance Published November 2019

Neratinib for extended adjuvant treatment of hormone receptor-positive, HER2-positive early stage breast cancer after adjuvant trastuzumab (TA612)

Evidence-based recommendations on neratinib (Nerlynx) for extended adjuvant treatment of hormone receptor-positive, HER2-positive early stage breast cancer

Technology appraisal guidance Published November 2019

Acute kidney injury

Everything NICE has said on preventing, detecting and managing acute kidney injury in an interactive flowchart

NICE Pathway Published August 2013 Last updated November 2019

Familial breast cancer: classification, care and managing breast cancer and related risks in people with a family history of breast cancer (CG164)

This guideline covers care for people with a family history of breast, ovarian or another related (prostate or pancreatic) cancer. It aims to improve the long-term health of these families by describing strategies to reduce the risk of and promote early detection of breast cancer (including genetic testing and mammography). It also includes advice on treatments (tamoxifen, raloxifene) and surgery (mastectomy).

Clinical guideline Published June 2013 Last updated November 2019

Unintentional injuries among under-15s

Preventing unintentional injuries among under-15s in the home, on the road and in outdoor play and leisure environments.

NICE Pathway Published November 2012 Last updated November 2019

Familial breast cancer

Everything NICE has said on assessing and managing familial breast cancer and related risks in people with a family history in an interactive flowchart

NICE Pathway Published October 2011 Last updated November 2019

Type 1 diabetes in adults

Everything NICE has said on diagnosing and managing type 1 diabetes in adults in an interactive flowchart

NICE Pathway Published May 2011 Last updated November 2019

Chronic kidney disease

Everything NICE has said on chronic kidney disease (renal failure) in an interactive flowchart

NICE Pathway Published May 2011 Last updated November 2019

Type 2 diabetes in adults

Everything NICE has said on managing type 2 diabetes in adults in an interactive flowchart

NICE Pathway Published May 2011 Last updated November 2019

Early and locally advanced breast cancer

Everything NICE has said on diagnosing and treating early and locally advanced breast cancer in an interactive flowchart

NICE Pathway Published May 2011 Last updated November 2019

Endocrine, nutritional and metabolic conditions

Everything NICE has said on endocrine, nutritional and metabolic conditions in an interactive flowchart

NICE Pathway Published December 2014 Last updated November 2019

Diabetes in children and young people

Everything NICE has said on diagnosing and managing type 1 and 2 diabetes in children and young people in an interactive flowchart

NICE Pathway Published May 2011 Last updated November 2019

Thyroid disease

Everything NICE has said on thyroid disease in children, young people and adults in an interactive flowchart

NICE Pathway Published November 2019

Cardiovascular disease prevention

Everything NICE has said on cardiovascular risk assessment and modifying blood lipids for preventing cardiovascular disease in adults

NICE Pathway Published July 2014 Last updated November 2019

Managing long-term sickness absence and capability to work

Everything NICE has said on managing long-term sickness absence and capability to work in an interactive flowchart

NICE Pathway Published January 2014 Last updated November 2019

What is the optimal way of discharging people approaching the end of their life from hospitals back to their place of residence?

Recommendation ID NG142/4 Question What is the optimal way of discharging people approaching the end of their life from hospitals back to

Research recommendation Published November 2019

Evidence on the safety and efficacy of midcarpal hemiarthroplasty for wrist arthritis is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG663/1 Question Evidence on the safety and efficacy of midcarpal hemiarthroplasty for wrist arthritis is inadequate

Research recommendation Published November 2019

When is it safe to stop contact casting in the treatment of acute Charcot arthropathy?

Recommendation ID NG19/12 Question When is it safe to stop contact casting in the treatment of acute Charcot arthropathy? Any explanatory

Research recommendation Published November 2019

Which risk stratification tools can be used to predict the likelihood of Charcot arthropathy?

Recommendation ID NG19/11 Question Which risk stratification tools can be used to predict the likelihood of Charcot arthropathy? Any

Research recommendation Published November 2019

Which of the electronic information-sharing systems perform best for the care of people approaching the end of their life?

Recommendation ID NG142/2 Question Which of the electronic information-sharing systems perform best for the care of people approaching the

Research recommendation Published November 2019

Does early review of service provision and referral to additional specialist palliative care services improve outcomes for adults with progressive non-cancer disease thought to be approaching the end of their life?

Recommendation ID NG142/1 Question Does early review of service provision and referral to additional specialist palliative care services

Research recommendation Published November 2019

What are the benefits of planned, regular community-based reviews compared with as-required review of non-cancer patients approaching the end of their life?

Recommendation ID NG142/3 Question What are the benefits of planned, regular community-based reviews compared with as-required review of

Research recommendation Published November 2019

What is the clinical effectiveness of maggot debridement therapy in the debridement of diabetic foot ulcers?

Recommendation ID NG19/10 Question What is the clinical effectiveness of maggot debridement therapy in the debridement of diabetic foot

Research recommendation Published November 2019

What is the clinical effectiveness of negative pressure wound therapy in the treatment of diabetic foot ulcers?

Recommendation ID NG19/9 Question What is the clinical effectiveness of negative pressure wound therapy in the treatment of diabetic foot

Research recommendation Published November 2019

How often should people with diabetic foot problems (foot ulcers, soft tissue infections, osteomyelitis or gangrene) be reviewed?

Recommendation ID NG19/8 Question How often should people with diabetic foot problems (foot ulcers, soft tissue infections, osteomyelitis

Research recommendation Published November 2019

Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe emphysema is inadequate in quantity and quality. Therefore the procedure should only be used in the context of research.

Recommendation ID IPG652/1 Question Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe

Research recommendation Published November 2019

Evidence on the safety and efficacy of high-intensity focused ultrasound for glaucoma is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG661/1 Question Evidence on the safety and efficacy of high-intensity focused ultrasound for glaucoma is inadequate

Research recommendation Published November 2019

The evidence on cardiac contractility modulation device implantation for heart failure raises no major safety concerns. However, the evidence on efficacy is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG655 Question The evidence on cardiac contractility modulation device implantation for heart failure raises no major

Research recommendation Published November 2019

Current evidence on the safety and efficacy of low-energy contact X‑ray brachytherapy (the Papillon technique) for locally advanced rectal cancer is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG659/1 Question Current evidence on the safety and efficacy of low-energy contact X‑ray brachytherapy (the Papillon

Research recommendation Published November 2019

Current evidence on the safety and efficacy of implant insertion for prominent ears is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG660/1 Question Current evidence on the safety and efficacy of implant insertion for prominent ears is inadequate in

Research recommendation Published November 2019

What is the most effective and safest AED to treat: established (usually lasting longer than 30 minutes) convulsive status epilepticus refractory convulsive status epilepticus?

Recommendation ID CG137/4 Question What is the most effective and safest AED to treat: established (usually lasting longer than 30

Research recommendation Published November 2019

What is the clinical and cost effectiveness of using different thresholds of LDL‑C concentration in primary care case finding?

Recommendation ID CG71/1 Question What is the clinical and cost effectiveness of using different thresholds of LDL‑C concentration in primary

Research recommendation Published November 2019

What are the implications of FH for the safety of a mother during pregnancy and what are the risks of fetal malformations attributable to pharmacological therapies

Recommendation ID CG71/5 Question What are the implications of FH for the safety of a mother during pregnancy and what are the risks of

Research recommendation Published November 2019

What is the effectiveness of different footwear, insoles and orthoses in the prevention of foot problems?

Recommendation ID NG19/7 Question What is the effectiveness of different footwear, insoles and orthoses in the prevention of foot problems

Research recommendation Published November 2019

What strategies may be useful in the prevention of Charcot arthropathy?

Recommendation ID NG19/4 Question What strategies may be useful in the prevention of Charcot arthropathy? Any explanatory notes(if

Research recommendation Published November 2019

When and with what criteria should people with diabetes be referred to the foot protection service or the multidisciplinary foot care service?

Recommendation ID NG19/2 Question When and with what criteria should people with diabetes be referred to the foot protection service or

Research recommendation Published November 2019

What are the symptoms of GORD in infants, children and young people with a neurodisability?

Recommendation ID NG1/1 Question What are the symptoms of GORD in infants, children and young people with a neurodisability? Any explanatory

Research recommendation Published November 2019

In people who experience symptoms of gastro-oesophageal reflux disease (GORD) or symptoms suggestive of GORD, what patient characteristics, risk factors and predictors indicate when endoscopy is needed to exclude Barrett's oesophagus?

Recommendation ID CG184/1 Question In people who experience symptoms of gastro-oesophageal reflux disease (GORD) or symptoms suggestive

Research recommendation Published November 2019