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HemaClear for bloodless surgical field during limb surgery (MIB187)

Advice on the use of HemaClear for bloodless surgical field during limb surgery to aid local decision making

Medtech innovation briefing Published July 2019

Endo-SPONGE for colorectal anastomotic leakage (MIB188)

Advice on the use of Endo-SPONGE for colorectal anastomotic leakage to aid local decision making

Medtech innovation briefing Published August 2019

The OPTIMIZER smart system for managing heart failure (MIB186)

Advice on the use of the OPTIMIZER smart system for managing heart failure to aid local decision making

Medtech innovation briefing Published June 2019

Doxylamine/pyridoxine (Xonvea) for treating nausea and vomiting of pregnancy (ES20)

Summary of the evidence on doxylamine/pyridoxine (Xonvea) for treating nausea and vomiting of pregnancy in women aged 18 years and older to inform local NHS

Evidence summary Published June 2019

The V.A.C. Veraflo Therapy system for infected wounds (MIB189)

Advice on the use of the V.A.C. Veraflo Therapy system for infected wounds to aid local decision making

Medtech innovation briefing Published September 2019

InterDry for intertrigo (MIB192)

Advice on the use of InterDry for intertrigo (inflammatory skin rash) to aid local decision making

Medtech innovation briefing Published September 2019

UroShield for preventing catheter-associated urinary tract infections (MIB191)

Advice on the use of UroShield for preventing catheter-associated urinary tract infections (CAUTI) to aid local decision making

Medtech innovation briefing Published September 2019

SuperNO2VA for the relief of upper airway obstruction in people with obstructive sleep apnoea (MIB190)

Advice on the use of SuperNO2VA for the relief of upper airway obstruction in people with obstructive sleep apnoea to aid local decision making

Medtech innovation briefing Published September 2019

Asthma: medicines safety priorities (KTT5)

KTT5 Asthma: medicines safety priorities Key points Inhaled corticosteroids (ICS) are

Key therapeutic topic Published January 2015 Last updated September 2019

Hypnotics (KTT6)

KTT6 Hypnotics Key points The risks associated with hypnotics (including melatonin)

Key therapeutic topic Published January 2015 Last updated September 2019

Antipsychotics in people living with dementia (KTT7)

KTT7 Antipsychotics in people living with dementia Key points The risks and limited

Key therapeutic topic Published January 2015 Last updated September 2019

Antimicrobial stewardship: prescribing antibiotics (KTT9)

KTT9 Antimicrobial stewardship: prescribing antibiotics Key points Antimicrobial resistance

Key therapeutic topic Published January 2015 Last updated September 2019

Medicines optimisation in chronic pain (KTT21)

KTT21 Medicines optimisation in chronic pain Key points Controlling chronic pain can

Key therapeutic topic Published January 2017 Last updated September 2019

Chemotherapy dose standardisation (KTT22)

KTT22 Chemotherapy dose standardisation Key points Chemotherapy dose standardisation

Key therapeutic topic Published February 2018 Last updated September 2019

Suicide prevention: optimising medicines and reducing access to medicines as a means of suicide (KTT24)

KTT24 Suicide prevention: optimising medicines and reducing access to medicines as a means of suicide Key points

Key therapeutic topic Published March 2019 Last updated September 2019

Psychotropic medicines in people with learning disabilities whose behaviour challenges (KTT19)

KTT19 Psychotropic medicines in people with learning disabilities whose behaviour challenges Key points

Key therapeutic topic Published January 2017 Last updated September 2019

Safer insulin prescribing (KTT20)

KTT20 Safer insulin prescribing Key points Several new insulin products have been launched

Key therapeutic topic Published January 2017 Last updated September 2019

Wound care products (KTT14)

KTT14 Wound care products Key points A large number of wound dressings are available

Key therapeutic topic Published January 2015 Last updated September 2019

Anticoagulants, including direct-acting oral anticoagulants (DOACs) (KTT16)

KTT16 Anticoagulants, including direct-acting oral anticoagulants (DOACs) Key points

Key therapeutic topic Published February 2016 Last updated September 2019

Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI (KTT17)

KTT17 Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI Key points

Key therapeutic topic Published February 2016 Last updated September 2019

Type 2 diabetes mellitus: medicines optimisation priorities (KTT12)

KTT12 Type 2 diabetes mellitus: medicines optimisation priorities Key points The NICE

Key therapeutic topic Published January 2015 Last updated September 2019

Alpha-Stim AID for anxiety (MIB193)

Advice on the use of Alpha-Stim AID for anxiety to aid local decision making

Medtech innovation briefing Published September 2019

Shared decision making (KTT23)

KTT23 Shared decision making Key points In the context of medicines optimisation, shared

Key therapeutic topic Published March 2019 Last updated September 2019

Lipid-modifying drugs (KTT3)

KTT3 Lipid-modifying drugs Key points The NICE guideline on cardiovascular disease:

Key therapeutic topic Published January 2015 Last updated September 2019

Multimorbidity and polypharmacy (KTT18)

KTT18 Multimorbidity and polypharmacy Key points Multimorbidity is associated with

Key therapeutic topic Published January 2017 Last updated September 2019

What is the clinical and cost effectiveness of intermittent auscultation compared with continuous cardiotocography for women in labour who have had a previous caesarean section?

Recommendation ID NG121/5 Question What is the clinical and cost effectiveness of intermittent auscultation compared with continuous cardiotocography

Research recommendation Published August 2019

Are progesterone or progestogens effective in treating threatened miscarriage?

Recommendation ID NG136/3 Question Are progesterone or progestogens effective in treating threatened miscarriage? Any explanatory notes(if

Research recommendation Published August 2019

Does caesarean section protect against cerebral haemorrhage in women with a history of subarachnoid haemorrhage or cerebrovascular malformation?

Recommendation ID NG121/1 Question Does caesarean section protect against cerebral haemorrhage in women with a history of subarachnoid haemorrhage

Research recommendation Published August 2019

What is the best technique for delivering surfactant in a minimally invasive manner?

Recommendation ID NG124/2 Question What is the best technique for delivering surfactant in a minimally invasive manner? Any explanatory

Research recommendation Published August 2019

What clinical features and laboratory investigations can be used to better stratify risk for women in labour with signs of sepsis (including fever and tachycardia)?

Recommendation ID NG121/4 Question What clinical features and laboratory investigations can be used to better stratify risk for women in

Research recommendation Published August 2019

Does targeting higher oxygen saturations of 92% to 97% in preterm babies lead to improved survival without significant complications?

Recommendation ID NG124/4 Question Does targeting higher oxygen saturations of 92% to 97% in preterm babies lead to improved survival without...

Research recommendation Published August 2019

What is the effectiveness of high-pressure non-invasive positive pressure ventilation (NIPPV) compared with continuous positive airways pressure (CPAP) flow driver as the primary mode of ventilation?

Recommendation ID NG124/1 Question What is the effectiveness of high-pressure non-invasive positive pressure ventilation (NIPPV) compared

Research recommendation Published August 2019

Is obesity an independent risk factor for perinatal morbidity and mortality?

Recommendation ID NG121/3 Question Is obesity an independent risk factor for perinatal morbidity and mortality? Any explanatory notes(if

Research recommendation Published August 2019

In women with confirmed miscarriage, does the type of management strategy (expectant, medical and surgical) impact on women's experience, including psychological and emotional outcomes?

Recommendation ID NG126/4 Question In women with confirmed miscarriage, does the type of management strategy (expectant, medical and surgical)

Research recommendation Published August 2019

What are the costs associated with best supportive care?

Recommendation ID TA575/1 Question What are the costs associated with best supportive care? Any explanatory notes(if applicable)

Research recommendation Published August 2019

What is the long-term effectiveness of bladder wall injection with botulinum toxin type A for overactive bladder in women?

Recommendation ID NG123/6 Question What is the long-term effectiveness of bladder wall injection with botulinum toxin type A for overactive

Research recommendation Published June 2019

What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary incontinence and pelvic organ prolapse in women?

Recommendation ID NG123/5 Question What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary incontinence

Research recommendation Published June 2019

What is the effectiveness of ultrasound-guided visualisation compared with clinical assessment to identify complications after mesh surgery for stress urinary incontinence or pelvic organ prolapse in women?

Recommendation ID NG123/3 Question What is the effectiveness of ultrasound-guided visualisation compared with clinical assessment to identify

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of immunotherapy in people with stage IIIA-N2 non-small-cell lung cancer following multimodality treatment including surgery?

Recommendation ID NG122/1 Question What is the effectiveness and cost effectiveness of immunotherapy in people with stage IIIA-N2 non-small-cell

Research recommendation Published June 2019

What is the effectiveness of pain management for women who present with chronic pain 3 months after mesh surgery for stress urinary incontinence or pelvic organ prolapse?

Recommendation ID NG123/8 Question What is the effectiveness of pain management for women who present with chronic pain 3 months after mesh

Research recommendation Published June 2019

What is the effectiveness of colpocleisis compared with sacrospinous fixation for pelvic organ prolapse in elderly women?

Recommendation ID NG123/2 Question What is the effectiveness of colpocleisis compared with sacrospinous fixation for pelvic organ prolapse

Research recommendation Published June 2019

What is the effectiveness and safety of anticholinergic medicines for overactive bladder in older women?

Recommendation ID NG123/1 Question What is the effectiveness and safety of anticholinergic medicines for overactive bladder in older women

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of stereotactic ablative radiotherapy (SABR) compared with surgery (for example, sublobar, wedge resection, lobectomy) for people with non-small-cell lung cancer (stage I and IIA) in whom surgery is suitable?

Recommendation ID NG122/2 Question What is the effectiveness and cost effectiveness of stereotactic ablative radiotherapy (SABR) compared

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of prophylactic cranial irradiation compared with routine MRI follow-up in people with extensive-stage small-cell lung cancer without brain metastases?

Recommendation ID NG122/4 Question What is the effectiveness and cost effectiveness of prophylactic cranial irradiation compared with routine

Research recommendation Published June 2019

What are the long-term outcomes, including patient satisfaction, from the use of pessaries compared with surgery for pelvic organ prolapse in women?

Recommendation ID NG123/4 Question What are the long-term outcomes, including patient satisfaction, from the use of pessaries compared with

Research recommendation Published June 2019

What is the most effective surgical management for women with both stress urinary incontinence and pelvic organ prolapse, including the sequence of interventions?

Recommendation ID NG123/7 Question What is the most effective surgical management for women with both stress urinary incontinence and pelvic

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of routinely performing contrast-enhanced brain CT at the time of initial diagnosis and/or staging CT?

Recommendation ID NG122/3 Question What is the effectiveness and cost effectiveness of routinely performing contrast-enhanced brain CT at

Research recommendation Published June 2019

Is the application of antiseptics and antibiotics in the operative field before wound closure, clinically and cost effective in reducing surgical site infection rates?

Recommendation ID NG125/4 Question Is the application of antiseptics and antibiotics in the operative field before wound closure, clinically

Research recommendation Published August 2019

What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in the prevention of surgical site infection when applied to the skin before incision?

Recommendation ID NG125/3 Question What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in

Research recommendation Published August 2019

Which patient groups, contamination groups and which layers gain the most benefit from the use of triclosan-coated or triclosan-impregnated sutures?

Recommendation ID NG125/5 Question Which patient groups, contamination groups and which layers gain the most benefit from the use of triclosan-coated

Research recommendation Published August 2019