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National Early Warning Score systems that alert to deteriorating adult patients in hospital (MIB205)

NICE has developed a medtech innovation briefing (MIB) on National Early Warning Score systems that alert to deteriorating adult patients in hospital

Medtech innovation briefing Published February 2020

Plus Sutures for preventing surgical site infection (MIB204)

NICE has developed a medtech innovation briefing (MIB) on Plus Sutures for preventing surgical site infection

Medtech innovation briefing Published February 2020

Antimicrobial prescribing: meropenem with vaborbactam (ES21)

Summary of the evidence on antimicrobial prescribing of meropenem with vaborbactam (Vaborem) to inform local NHS planning and decision making

Evidence summary: antimicrobial prescribing Published November 2019

Antimicrobial prescribing: ceftolozane with tazobactam for treating hospital-acquired pneumonia, including ventilator-associated pneumonia (ES22)

Summary of the evidence on the antimicrobial prescribing of ceftolozane with tazobactam for hospital-acquired pneumonia, including ventilator-associated

Evidence summary: antimicrobial prescribing Published December 2019

PulmoVista 500 for monitoring ventilation in critical care (MIB203)

Advice on the use of PulmoVista 500 for monitoring ventilation in critical care to aid local decision making

Medtech innovation briefing Published December 2019

eXroid for internal haemorrhoids (MIB201)

Advice on the use of eXroid, using direct current electrotherapy to blood vessels of internal haemorrhoid to shrink haemorrhoids, to aid local decision making

Medtech innovation briefing Published December 2019

PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection (MIB200)

Advice on the use of PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection to aid local decision making

Medtech innovation briefing Published December 2019

Optowire for measuring fractional flow reserve (MIB199)

Advice on the use of Optowire (sterile, fibreoptic-based, disposable guide wire) for measuring fractional flow reserve (FFR) to aid local decision making

Medtech innovation briefing Published December 2019

AmnioSense for unexplained vaginal wetness in pregnancy (MIB198)

Advice on the use of AmnioSense (non-invasive diagnostic pad/liner) for unexplained vaginal wetness in pregnancy to aid local decision making

Medtech innovation briefing Published November 2019

LQD Spray for treating acute and chronic wounds (MIB202)

Advice on the use of LQD Spray (spray-on dressing containing modified biopolymer chitosan FH02) for treating acute/chronic wounds to aid local decision making

Medtech innovation briefing Published December 2019

The percentage of women, on the register, prescribed an oral or patch contraceptive method in the preceding 12 months who have also received information from the contractor about long acting reversible methods of contraception in the preceding 12 months (Inherited)

The percentage of women, on the register, prescribed an oral or patch contraceptive method in the preceding 12 months who have also received...

General practice indicator suitable for use in the QOF Published February 2020

The percentage of women with schizophrenia, bipolar affective disorder or other psychoses under the age of 45 years who have been given information and advice about pregnancy, conception or contraception tailored to their pregnancy and contraceptive intentions recorded in the preceding 12 months.

The percentage of women with schizophrenia, bipolar affective disorder or other psychoses under the age of 45 years who have been given information...

General practice indicator suitable for use in the QOF Published February 2020

The percentage of women with epilepsy aged 18 or over and who have not attained the age of 45 who are taking antiepileptic drugs who have a record of being given information and advice about pregnancy or conception or contraception tailored to their pregnancy and contraceptive intentions recorded in the preceding 12 months

The percentage of women with epilepsy aged 18 or over and who have not attained the age of 45 who are taking antiepileptic drugs who have a record of...

General practice indicator suitable for use in the QOF Published February 2020

What interventions are effective and cost effective at raising awareness of the health risks of damp and mould in the home?

Recommendation ID NG149/5 Question What interventions are effective and cost effective at raising awareness of the health risks of damp

Research recommendation Published February 2020

Which signs and symptoms (or combinations of signs and symptoms) predict a diagnosis of Kawasaki disease in children under 5 presenting with fever lasting 5 days or more?

Recommendation ID NG143/8 Question Which signs and symptoms (or combinations of signs and symptoms) predict a diagnosis of Kawasaki disease

Research recommendation Published February 2020

What is the clinical and cost effectiveness of cannabis-based medicinal products other than THC: CBD spray for children, young people and adults with spasticity? In particular, what is the impact of spasticity on improvements in quality of life?

Recommendation ID NG144/5 Question What is the clinical and cost effectiveness of cannabis-based medicinal products other than THC: CBD

Research recommendation Published February 2020

What is the effectiveness of personal health and social care budgets in supporting carers to return to work, education or training?

Recommendation ID NG150/2 Question What is the effectiveness of personal health and social care budgets in supporting carers to return to

Research recommendation Published February 2020

What are the clinically and cost-effective surgical approaches to managing complicated acute diverticulitis, including timing of surgery (elective or emergency)?

Recommendation ID NG147/5 Question What are the clinically and cost-effective surgical approaches to managing complicated acute diverticulitis

Research recommendation Published February 2020

What training, support or interventions help to reduce caring-related accidents or incidents?

Recommendation ID NG150/3 Question What training, support or interventions help to reduce caring-related accidents or incidents? Any

Research recommendation Published February 2020

What are the risk factors for diverticulosis progressing to diverticular disease?

Recommendation ID NG147/6 Question What are the risk factors for diverticulosis progressing to diverticular disease? Any explanatory

Research recommendation Published February 2020

Can risk of contrast-induced acute kidney injury be stratified by eGFR thresholds?

Recommendation ID NG148/1 Question Can risk of contrast-induced acute kidney injury be stratified by eGFR thresholds? Any explanatory

Research recommendation Published February 2020

What is the effectiveness, cost effectiveness and acceptability of the whole family approach to carers' assessments?

Recommendation ID NG150/1 Question What is the effectiveness, cost effectiveness and acceptability of the whole family approach to carers'

Research recommendation Published February 2020

What is the cost effectiveness and safety of non-surgical ablation and stereotactic body radiotherapy compared to resection for people with metastatic colorectal cancer in the lung amenable to local treatment?

Recommendation ID NG151/1 Question What is the cost effectiveness and safety of non-surgical ablation and stereotactic body radiotherapy

Research recommendation Published February 2020

Does the addition of THC to CBD have an effect on seizure frequency, brain structure and neuropsychological performance when compared with both CBD alone and placebo in epileptic disorders in children, young people and adults?

Recommendation ID NG144/4 Question Does the addition of THC to CBD have an effect on seizure frequency, brain structure and neuropsychological

Research recommendation Published February 2020

What information and support do people with diverticulosis, diverticular disease or acute diverticulitis need?

Recommendation ID NG147/4 Question What information and support do people with diverticulosis, diverticular disease or acute diverticulitis

Research recommendation Published February 2020

Evidence on the safety of irreversible electroporation for primary liver cancer shows serious but infrequent and well-recognised complications. Evidence on its efficacy is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG664/1 Question Evidence on the safety of irreversible electroporation for primary liver cancer shows serious but infrequent

Research recommendation Published February 2020

What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism?

Recommendation ID NG145/11 Question What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism?

Research recommendation Published February 2020

What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the home?

Recommendation ID NG149/3 Question What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the

Research recommendation Published February 2020

What is the clinical and cost effectiveness of a block and replace regimen compared with a titration regimen of antithyroid drugs for Graves' disease?

Recommendation ID NG145/8 Question What is the clinical and cost effectiveness of a block and replace regimen compared with a titration

Research recommendation Published February 2020

What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment for adults with chemotherapy-induced nausea and vomiting which persists with optimised conventional antiemetics?

Recommendation ID NG144/6 Question What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment

Research recommendation Published February 2020

What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment in babies, children and young people with chemotherapy-induced nausea or vomiting which persists with optimised conventional antiemetics?

Recommendation ID NG144/7 Question What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment

Research recommendation Published February 2020

What is the relative effectiveness and cost effectiveness of different oral fluids and different oral fluid regimens, both with and without oral N-acetylcysteine, at preventing contrast-induced acute kidney injury?

Recommendation ID NG148/2 Question What is the relative effectiveness and cost effectiveness of different oral fluids and different oral

Research recommendation Published February 2020

What is the clinical and cost effectiveness of dosimetry-guided radioactive iodine strategies for hyperthyroidism?

Recommendation ID NG145/5 Question What is the clinical and cost effectiveness of dosimetry-guided radioactive iodine strategies for hyperthyroidism

Research recommendation Published February 2020

What is the clinical and cost effectiveness of different durations of antithyroid drug regimens for people with T3 thyrotoxicosis due to Graves' disease?

Recommendation ID NG145/6 Question What is the clinical and cost effectiveness of different durations of antithyroid drug regimens for people

Research recommendation Published February 2020

Are there subgroups of people with Graves' disease who have a particularly good response to antithyroid drugs?

Recommendation ID NG145/3 Question Are there subgroups of people with Graves' disease who have a particularly good response to antithyroid

Research recommendation Published February 2020

What is the clinical and cost effectiveness of CBD in epileptic disorders in children, young people and adults?

Recommendation ID NG144/3 Question What is the clinical and cost effectiveness of CBD in epileptic disorders in children, young people and

Research recommendation Published February 2020

For adults with fibromyalgia or persistent treatment-resistant neuropathic pain, what is the clinical and cost effectiveness of cannabidiol (CBD), containing no, or traces of, delta-9-tetrahydrocannabinol (THC), as an add-on to standard treatment?

Recommendation ID NG144/1 Question For adults with fibromyalgia or persistent treatment-resistant neuropathic pain, what is the clinical

Research recommendation Published February 2020

What is the most clinically and cost-effective conservative management for preventing diverticular disease in people with diverticulosis?

Recommendation ID NG147/2 Question What is the most clinically and cost-effective conservative management for preventing diverticular disease

Research recommendation Published February 2020

Further evidence to address the uncertainties in the current clinical evidence,including the impact of gammaCore on all treatments and care as well as itslong-term benefits, would be welcome.

Recommendation ID MTG46/1 Question Further evidence to address the uncertainties in the current clinical evidence,including the impact of

Research recommendation Published February 2020

What is the health impact of exposure to individual air pollutants alone or combined with each other in the home?

Recommendation ID NG149/1 Question What is the health impact of exposure to individual air pollutants alone or combined with each other

Research recommendation Published February 2020

What is the effectiveness and cost effectiveness of interventions to improve indoor air quality at home for people without pre‑existing health conditions?

Recommendation ID NG149/2 Question What is the effectiveness and cost effectiveness of interventions to improve indoor air quality at home

Research recommendation Published February 2020

What interventions are effective and cost effective in supporting return to work, in all workplaces including micro-, small- and medium-sized organisations, after long-term sickness absence in the UK?

Recommendation ID NG146/1 Question What interventions are effective and cost effective in supporting return to work, in all workplaces including

Research recommendation Published February 2020

For people with common mental health conditions, what interventions are effective and cost effective in reducing long-term sickness absence and supporting return to work in the UK?

Recommendation ID NG146/3 Question For people with common mental health conditions, what interventions are effective and cost effective

Research recommendation Published February 2020