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Pertuzumab with trastuzumab and docetaxel for treating HER2-positive breast cancer (TA509)

Evidence-based recommendations on pertuzumab (Perjeta) for HER2-positive, locally recurrent or metastatic (secondary) breast cancer in adults

Technology appraisal guidance Published March 2018

Rivaroxaban for preventing atherothrombotic events in people with coronary or peripheral artery disease (TA607)

Evidence-based recommendations on rivaroxaban (Xarelto) for preventing atherothrombotic events in adults with coronary or peripheral artery disease

Technology appraisal guidance Published October 2019

Olaparib for maintenance treatment of BRCA mutation-positive advanced ovarian, fallopian tube or peritoneal cancer after response to first-line platinum-based chemotherapy (TA598)

Evidence-based recommendations on olaparib (Lynparza) for treating BRCA mutation-positive, advanced ovarian, fallopian tube or primary peritoneal cancer

Technology appraisal guidance Published August 2019

Atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers (the CoaguChek XS system) (DG14)

Evidence-based recommendations on point-of-care coagulometers (the CoaguChek XS system) to self-monitor blood clotting

Diagnostics guidance Published September 2014 Last updated December 2017

Integrated multiplex PCR tests for identifying gastrointestinal pathogens in people with suspected gastroenteritis (xTAG Gastrointestinal Pathogen Panel, FilmArray GI Panel and Faecal Pathogens B assay) (DG26)

Evidence-based recommendations on integrated multiplex polymerase chain tests for identifying gastrointestinal pathogens in suspected gastroenteritis

Diagnostics guidance Published January 2017

XprESS multi sinus dilation system for treating chronic sinusitis (MTG30)

Evidence-based recommendations on the XprESS multi-sinus dilation system for treating chronic sinusitis after medical treatment has failed

Medical technologies guidance Published December 2016

MiraQ for assessing graft flow during coronary artery bypass graft surgery (MTG8)

Evidence-based recommendations on MiraQ for assessing graft flow during coronary artery bypass graft surgery

Medical technologies guidance Published November 2011 Last updated February 2018

New generation cardiac CT scanners (Aquilion ONE, Brilliance iCT, Discovery CT750 HD and Somatom Definition Flash) for cardiac imaging in people with suspected or known coronary artery disease in whom imaging is difficult with earlier generation CT scanners (DG3)

Evidence-based recommendations on new generation computed tomography (CT) scanners for cardiac imaging for suspected or known coronary artery disease

Diagnostics guidance Published January 2012 Last updated July 2017

Virtual chromoendoscopy to assess colorectal polyps during colonoscopy (DG28)

Evidence-based recommendations on virtual chromoendoscopy (VCE) using NBI, FICE or i-scan to assess colorectal polyps of 5 mm or less during colonoscopy

Diagnostics guidance Published May 2017

Ambu aScope4 Broncho for use in unexpected difficult airways (MTG14)

Evidence-based recommendations on the Ambu aScope4 Broncho for use in unexpected difficult airways

Medical technologies guidance Published July 2013 Last updated June 2019

Irreversible electroporation for treating pancreatic cancer (IPG579)

Evidence-based recommendations on irreversible electroporation (IRE) for treating pancreatic cancer

Interventional procedures guidance Published May 2017

Extraurethral (non-circumferential) retropubic adjustable compression devices for stress urinary incontinence in women (IPG576)

Evidence-based recommendations on extraurethral (non-circumferential) retropubic adjustable compression devices for stress urinary incontinence in women

Interventional procedures guidance Published March 2017

Trabecular stent bypass microsurgery for open-angle glaucoma (IPG575)

Evidence-based recommendations on trabecular stent bypass microsurgery for open-angle glaucoma (damaged optic nerve)

Interventional procedures guidance Published February 2017

Radiation therapy for early Dupuytren's disease (IPG573)

Evidence-based recommendations on radiation therapy (low energy X-rays) for treating early Dupuytren’s contractures in adults

Interventional procedures guidance Published December 2016

Extracorporeal shockwave therapy for Achilles tendinopathy (IPG571)

Evidence-based recommendations on extracorporeal shockwave therapy for treating Achilles tendinopathy in adults

Interventional procedures guidance Published December 2016

Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy for treating morbid obesity (IPG569)

Evidence-based recommendations on single-anastomosis duodeno-ileal bypass with sleeve gastrectomy for treating morbid obesity

Interventional procedures guidance Published November 2016

Percutaneous insertion of craniocaudal expandable implants for vertebral compression fracture (IPG568)

Evidence-based recommendations on percutaneous insertion of craniocaudal expandable implants for vertebral compression fracture in adults

Interventional procedures guidance Published November 2016

Infracoccygeal sacropexy using mesh to repair uterine prolapse (IPG582)

Evidence-based recommendations on infracoccygeal sacropexy using mesh to repair uterine (womb) prolapse in women

Interventional procedures guidance Published June 2017

Infracoccygeal sacropexy using mesh to repair vaginal vault prolapse (IPG581)

Evidence-based recommendations on infracoccygeal sacropexy using mesh to repair vaginal vault prolapse in women

Interventional procedures guidance Published June 2017

Sacrocolpopexy using mesh to repair vaginal vault prolapse (IPG583)

Evidence-based recommendations on sacropolpopexy using mesh to repair vaginal vault prolapse in women

Interventional procedures guidance Published June 2017

Uterine suspension using mesh (including sacrohysteropexy) to repair uterine prolapse (IPG584)

Evidence-based recommendations on uterine suspension using mesh (including sacrohysteropexy) to repair uterine prolapse in women

Interventional procedures guidance Published June 2017

SecurAcath for securing percutaneous catheters (MTG34)

Evidence-based recommendations on SecurAcath for securing percutaneous catheters (central venous catheters/CVCs)

Medical technologies guidance Published June 2017

Endoscopic full thickness removal of non-lifting colonic polyps (IPG580)

Evidence-based recommendations on endoscopic full thickness removal of non-lifting colonic polyps (colonic adenomas/growths)

Interventional procedures guidance Published May 2017

Multiple frequency bioimpedance devices to guide fluid management in people with chronic kidney disease having dialysis (DG29)

Evidence-based recommendations on multi frequency bioimpedance devices to guide fluid management for people with chronic kidney disease having dialysis

Diagnostics guidance Published June 2017

moorLDI2-BI: a laser doppler blood flow imager for burn wound assessment (MTG2)

Evidence-based recommendations on the moorLDI2-BI a laser doppler blood flow imager for burn wound assessment

Medical technologies guidance Published March 2011 Last updated August 2017

The Debrisoft monofilament debridement pad for use in acute or chronic wounds (MTG17)

Evidence-based recommendations on the Debrisoft monofilament debridement pad for use in acute or chronic wounds

Medical technologies guidance Published March 2014 Last updated March 2019

The Sherlock 3CG Tip Confirmation System for placement of peripherally inserted central catheters (MTG24)

Evidence-based recommendations on the Sherlock 3CG Tip Confirmation System for placement of peripherally inserted central catheters

Medical technologies guidance Published March 2015 Last updated May 2019

PleurX peritoneal catheter drainage system for vacuum-assisted drainage of treatment-resistant, recurrent malignant ascites (MTG9)

Evidence-based recommendations on PleurX peritoneal catheter drainage system for vacuum-assisted drainage of treatment-resistant, recurrent malignant ascites

Medical technologies guidance Published March 2012 Last updated February 2018

ENDURALIFE powered CRT-D devices for treating heart failure (MTG33)

Evidence-based recommendations on ENDURALIFE-powered cardiac resynchronisation therapy-defibrillator (CRT-D) devices for treating heart failure

Medical technologies guidance Published March 2017

HeartFlow FFRCT for estimating fractional flow reserve from coronary CT angiography (MTG32)

Evidence-based recommendations on HeartFlow FFRCT for estimating fractional flow reserve from coronary CT angiography

Medical technologies guidance Published February 2017

HumiGard for preventing inadvertent perioperative hypothermia (MTG31)

Evidence-based recommendations on HumiGard for preventing inadvertent perioperative hypothermia in patients having abdominal surgery

Medical technologies guidance Published February 2017

EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing (MTG12)

Evidence-based recommendations on the EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing

Medical technologies guidance Published January 2013 Last updated October 2019

Pipeline Flex embolisation device with Shield Technology for the treatment of complex intracranial aneurysms (MTG10)

Evidence-based recommendations on the Pipeline Flex embolisation device with Shield Technology for the treatment of complex intracranial aneurysms

Medical technologies guidance Published May 2012 Last updated January 2019

Transcatheter aortic valve implantation for aortic stenosis (IPG586)

Evidence-based recommendations on transcatheter aortic valve implantation (TAVI) for aortic stenosis

Interventional procedures guidance Published July 2017

Laparoscopic insertion of a magnetic titanium ring for gastro-oesophageal reflux disease (IPG585)

Evidence-based recommendations on laparoscopic insertion of a magnetic titanium ring for gastro-oesophageal reflux disease (GORD) in adults

Interventional procedures guidance Published July 2017

Quantitative faecal immunochemical tests to guide referral for colorectal cancer in primary care (DG30)

Evidence-based recommendations on quantitative faecal immunochemical tests (OC Sensor, HM-JACKarc and FOB Gold) to guide GP referral for colorectal cancer

Diagnostics guidance Published July 2017

Adjunctive colposcopy technologies for assessing suspected cervical abnormalities: the DYSIS colposcope with DYSISmap and the ZedScan I (DG32)

Evidence-based recommendations on DYSIS colposcope with DYSISmap and ZedScan I for assessing suspected cervical abnormalities in people having colposcopy

Diagnostics guidance Published April 2018

Microinvasive subconjunctival insertion of a trans-scleral gelatin stent for primary open-angle glaucoma (IPG612)

Evidence-based recommendations on microinvasive subconjunctival insertion of a trans-scleral gelatin stent (tube) for primary open-angle glaucoma in adults

Interventional procedures guidance Published April 2018

Prostate artery embolisation for lower urinary tract symptoms caused by benign prostatic hyperplasia (IPG611)

Evidence-based recommendations on prostate artery embolisation for lower urinary tract symptoms caused by benign prostatic hyperplasia in adults

Interventional procedures guidance Published April 2018

Nerve transfer to partially restore upper limb function in tetraplegia (IPG610)

Evidence-based recommendations on nerve transfer to partially restore upper limb function in people with tetraplegia (quadriplegia; paralysis of arms and legs)

Interventional procedures guidance Published April 2018

Robot-assisted kidney transplant (IPG609)

Evidence-based recommendations on robot-assisted kidney transplant in adults

Interventional procedures guidance Published April 2018

Percutaneous balloon valvuloplasty for fetal critical aortic stenosis (IPG613)

Evidence-based recommendations on percutaneous balloon valvuloplasty for fetal critical aortic stenosis

Interventional procedures guidance Published May 2018

Endoscopic bipolar radiofrequency ablation for treating biliary obstruction caused by cancer (IPG614)

Evidence-based recommendations on endoscopic bipolar radiofrequency ablation (heat energy) to treat biliary obstruction (bile duct blockage) caused by cancer

Interventional procedures guidance Published May 2018

Transurethral water vapour ablation for lower urinary tract symptoms caused by benign prostatic hyperplasia (IPG625)

Evidence-based recommendations on transurethral water vapour ablation for lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)

Interventional procedures guidance Published August 2018

Laparoscopic ventral mesh rectopexy for internal rectal prolapse (IPG618)

Evidence-based recommendations on laparoscopic ventral mesh rectopexy for internal rectal prolapse in adults

Interventional procedures guidance Published June 2018

Unilateral MRI-guided focused ultrasound thalamotomy for treatment-resistant essential tremor (IPG617)

Evidence-based recommendations on unilateral MRI-guided focused ultrasound thalamotomy for treatment-resistant essential tremor in adults

Interventional procedures guidance Published June 2018

Biomarker tests to help diagnose preterm labour in women with intact membranes (DG33)

Evidence-based recommendations on biomarker tests (Actim Partus, PartoSure, Rapid fFN 10Q Cassette) to diagnose preterm labour in women with intact membranes

Diagnostics guidance Published July 2018

Intranasal phototherapy for allergic rhinitis (IPG616)

Evidence-based recommendations on intranasal phototherapy to reduce inflammation inside the nose in allergic rhinitis in adults

Interventional procedures guidance Published June 2018

Low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures (IPG623)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of delayed-union and non-union fractures

Interventional procedures guidance Published July 2018

Low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk of non-healing (IPG622)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of fresh fractures at high risk of non-healing

Interventional procedures guidance Published July 2018