NICE is unable to make a recommendation about the use in the NHS of pomalidomide (Imnovid) with bortezomib and dexamethasone for relapsed or refractory myeloma
NICE is unable to make a recommendation about the use in the NHS of bezlotoxumab (Zinplava) for preventing recurrent Clostridium difficile infection in adults
This guideline covers care for women of any age (including girls and young women under 18) who request an abortion. It aims to improve the organisation of services and make them easier for women to access. Detailed recommendations on conducting abortions at different gestational stages are also included, to ensure that women get the safest and most effective care possible.
Evidence-based recommendations on the 3M Tegaderm CHG IV securement dressing for central venous and arterial catheter insertion sites
This guideline covers diagnosing and managing community- and hospital-acquired pneumonia in adults. It aims to improve accurate assessment and diagnosis of pneumonia to help guide antibiotic prescribing and ensure that people receive the right treatment.
This guideline sets out an antimicrobial prescribing strategy for adults, young people, children and babies aged 72 hours and over with a confirmed diagnosis of community-acquired pneumonia. It aims to optimise antibiotic use and reduce antibiotic resistance.
This guideline sets out an antimicrobial prescribing strategy for adults, young people, children and babies aged 72 hours and over with a confirmed diagnosis of hospital-acquired pneumonia. It does not cover ventilator-associated pneumonia. It aims to optimise antibiotic use and reduce antibiotic resistance.
This guideline covers the assessment and early management of head injury in children, young people and adults. It promotes effective clinical assessment so that people receive the right care for the severity of their head injury, including referral directly to specialist care if needed.
This guideline covers recognising, diagnosing and managing attention deficit hyperactivity disorder (ADHD) in children, young people and adults. It aims to improve recognition and diagnosis, as well as the quality of care and support for people with ADHD.
This guideline covers preventing, identifying and managing latent and active tuberculosis (TB) in children, young people and adults. It aims to improve ways of finding people who have TB in the community and recommends that everyone under 65 with latent TB should be treated. It describes how TB services should be organised, including the role of the TB control board.
Evidence-based recommendations on implant insertion for prominent ears in children, young people and adults
Evidence-based recommendations on pembrolizumab (Keytruda) with carboplatin and paclitaxel for untreated metastatic squamous non-small-cell lung cancer (NSCLC)
Evidence-based recommendations on sodium zirconium cyclosilicate (Lokelma) for treating hyperkalaemia (elevated blood potassium levels) in adults
This guideline covers the care that should be offered to women with a twin or triplet pregnancy in addition to the routine care that is offered to all women during pregnancy. It aims to reduce the risk of complications and improve outcomes for women and their babies.
This guideline covers when to offer caesarean section, procedural aspects of the operation and care after caesarean section. It aims to improve the consistency and quality of care for women who are considering a caesarean section or have had a caesarean section in the past and are now pregnant again.
Evidence-based recommendations on benralizumab (Fasenra) for treating severe eosinophilic asthma (SEA; elevated levels of eosinophils in blood) in adults
This guideline covers the care and management of type 2 diabetes in adults (aged 18 and over). It focuses on patient education, dietary advice, managing cardiovascular risk, managing blood glucose levels, and identifying and managing long-term complications.
This guideline covers identifying and treating primary hypertension (high blood pressure) in people aged 18 and over, including people with type 2 diabetes. It aims to reduce the risk of cardiovascular problems such as heart attacks and strokes by helping healthcare professionals to diagnose hypertension accurately and treat it effectively.
Evidence-based recommendations on dapagliflozin (Forxiga) with insulin for type 1 diabetes not controlled by insulin therapy alone in adults with a BMI of at
Evidence-based recommendations on olaparib (Lynparza) for treating BRCA mutation-positive, advanced ovarian, fallopian tube or primary peritoneal cancer
Evidence-based recommendations on risankizumab (Skyrizi) for treating moderate to severe plaque psoriasis in adults
Recommendation ID NG126/1 Question How does the timing and frequency of ultrasound examination affect diagnosis and outcomes of early pregnancy
Recommendation ID TA575/1 Question What are the costs associated with best supportive care? Any explanatory notes(if applicable)
Recommendation ID NG124/2 Question What is the best technique for delivering surfactant in a minimally invasive manner? Any explanatory
Recommendation ID NG121/1 Question Does caesarean section protect against cerebral haemorrhage in women with a history of subarachnoid haemorrhage
Recommendation ID NG121/4 Question What clinical features and laboratory investigations can be used to better stratify risk for women in
Recommendation ID NG136/3 Question Are progesterone or progestogens effective in treating threatened miscarriage? Any explanatory notes(if
Recommendation ID NG121/5 Question What is the clinical and cost effectiveness of intermittent auscultation compared with continuous cardiotocography
Recommendation ID NG124/5 Question What is the most effective combination of an analgesic with a neuromuscular blocker, or an analgesic
Recommendation ID NG124/4 Question Does targeting higher oxygen saturations of 92% to 97% in preterm babies lead to improved survival without...
Recommendation ID NG121/3 Question Is obesity an independent risk factor for perinatal morbidity and mortality? Any explanatory notes(if
Recommendation ID NG124/1 Question What is the effectiveness of high-pressure non-invasive positive pressure ventilation (NIPPV) compared
Recommendation ID NG121/2 Question Does the use of ultrasound of the lumbar spine improve siting of regional anaesthetic needles in pregnant
Recommendation ID NG125/1 Question What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination
Recommendation ID NG125/2 Question Is the use of chlorhexidine body wash associated with increased antimicrobial resistance? Any explanatory
Recommendation ID NG126/4 Question In women with confirmed miscarriage, does the type of management strategy (expectant, medical and surgical)
Recommendation ID NG126/1 Question A national evaluation of early pregnancy assessment unit service provision should be carried out to identify
Recommendation ID NG124/3 Question What is the effectiveness of diuretics compared with placebo in preventing bronchopulmonary dysplasia
Recommendation ID NG126/5 Question In women with ectopic pregnancy, does the type of intervention impact on women's experience, including
Recommendation ID NG125/5 Question Which patient groups, contamination groups and which layers gain the most benefit from the use of triclosan-coated
Recommendation ID TA574/1 Question What are the cost associated with best supportive care? Any explanatory notes(if applicable)
Recommendation ID NG125/3 Question What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in
Recommendation ID NG125/4 Question Is the application of antiseptics and antibiotics in the operative field before wound closure, clinically
Evidence-based recommendations on endovascular insertion of an intrasaccular wire-mesh blood-flow disruption device for intracranial aneurysms in adults
NICE is unable to make a recommendation about the use in the NHS of brentuximab vedotin (Adcetris) for untreated advanced Hodgkin lymphoma in adults
Evidence-based recommendations on patisiran (Onpattro) for treating hereditary transthyretin amyloidosis in adults with stage 1 and stage 2 polyneuropathy
Evidence-based recommendations on dacomitinib (Vizimpro) for locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer (NSCLC) in adults
Evidence-based recommendations on ribociclib (Kisqali) for hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer in adults
Evidence-based recommendations on low-energy contact X-ray brachytherapy (the Papillon technique) for locally advanced rectal cancer in adults
This guideline covers assessing and reducing the risk of venous thromboembolism (VTE or blood clots) and deep vein thrombosis (DVT) in people aged 16 and over in hospital. It aims to help healthcare professionals identify people most at risk and describes interventions that can be used to reduce the risk of VTE.