Updating results

What is the most clinically and cost-effective conservative management for preventing diverticular disease in people with diverticulosis?

Recommendation ID NG147/2 Question What is the most clinically and cost-effective conservative management for preventing diverticular disease

Research recommendation Published February 2020

What is the clinical and cost effectiveness of CBD in epileptic disorders in children, young people and adults?

Recommendation ID NG144/3 Question What is the clinical and cost effectiveness of CBD in epileptic disorders in children, young people

Research recommendation Published February 2020

What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment for adults with chemotherapy-induced nausea and vomiting which persists with optimised conventional antiemetics?

Recommendation ID NG144/6 Question What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment

Research recommendation Published February 2020

What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment in babies, children and young people with chemotherapy-induced nausea or vomiting which persists with optimised conventional antiemetics?

Recommendation ID NG144/7 Question What is the clinical and cost effectiveness of cannabis-based medicinal products as an add-on treatment

Research recommendation Published February 2020

What is the effectiveness and cost effectiveness of interventions to improve indoor air quality at home for people without pre‑existing health conditions?

Recommendation ID NG149/2 Question What is the effectiveness and cost effectiveness of interventions to improve indoor air quality at home

Research recommendation Published February 2020

What is the relative effectiveness and cost effectiveness of different oral fluids and different oral fluid regimens, both with and without oral N-acetylcysteine, at preventing contrast-induced acute kidney injury?

Recommendation ID NG148/2 Question What is the relative effectiveness and cost effectiveness of different oral fluids and different oral

Research recommendation Published February 2020

For adults with fibromyalgia or persistent treatment-resistant neuropathic pain, what is the clinical and cost effectiveness of cannabidiol (CBD), containing no, or traces of, delta-9-tetrahydrocannabinol (THC), as an add-on to standard treatment?

Recommendation ID NG144/1 Question For adults with fibromyalgia or persistent treatment-resistant neuropathic pain, what is the clinical

Research recommendation Published February 2020

Further evidence to address the uncertainties in the current clinical evidence,including the impact of gammaCore on all treatments and care as well as itslong-term benefits, would be welcome.

Recommendation ID MTG46/1 Question Further evidence to address the uncertainties in the current clinical evidence,including the impact

Research recommendation Published February 2020

What is the clinical and cost effectiveness of dosimetry-guided radioactive iodine strategies for hyperthyroidism?

Recommendation ID NG145/5 Question What is the clinical and cost effectiveness of dosimetry-guided radioactive iodine strategies for hyperthyroidism

Research recommendation Published February 2020

What are the clinically and cost-effective surgical approaches to managing complicated acute diverticulitis, including timing of surgery (elective or emergency)?

Recommendation ID NG147/5 Question What are the clinically and cost-effective surgical approaches to managing complicated acute diverticulitis

Research recommendation Published February 2020

What training, support or interventions help to reduce caring-related accidents or incidents?

Recommendation ID NG150/3 Question What training, support or interventions help to reduce caring-related accidents or incidents?

Research recommendation Published February 2020

What is the effectiveness of personal health and social care budgets in supporting carers to return to work, education or training?

Recommendation ID NG150/2 Question What is the effectiveness of personal health and social care budgets in supporting carers to return

Research recommendation Published February 2020

What is the cost effectiveness and safety of non-surgical ablation and stereotactic body radiotherapy compared to resection for people with metastatic colorectal cancer in the lung amenable to local treatment?

Recommendation ID NG151/1 Question What is the cost effectiveness and safety of non-surgical ablation and stereotactic body radiotherapy

Research recommendation Published February 2020

Which signs and symptoms (or combinations of signs and symptoms) predict a diagnosis of Kawasaki disease in children under 5 presenting with fever lasting 5 days or more?

Recommendation ID NG143/8 Question Which signs and symptoms (or combinations of signs and symptoms) predict a diagnosis of Kawasaki disease

Research recommendation Published February 2020

What is the clinical and cost effectiveness of cannabis-based medicinal products other than THC: CBD spray for children, young people and adults with spasticity? In particular, what is the impact of spasticity on improvements in quality of life?

Recommendation ID NG144/5 Question What is the clinical and cost effectiveness of cannabis-based medicinal products other than THC: CBD

Research recommendation Published February 2020

Does the addition of THC to CBD have an effect on seizure frequency, brain structure and neuropsychological performance when compared with both CBD alone and placebo in epileptic disorders in children, young people and adults?

Recommendation ID NG144/4 Question Does the addition of THC to CBD have an effect on seizure frequency, brain structure and neuropsychological

Research recommendation Published February 2020

What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism?

Recommendation ID NG145/11 Question What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism

Research recommendation Published February 2020

What are the emission profiles of indoor air pollutants released from building materials in a lived-in home environment?

Recommendation ID NG149/4 Question What are the emission profiles of indoor air pollutants released from building materials in a lived-in

Research recommendation Published February 2020

What information and support do people with diverticulosis, diverticular disease or acute diverticulitis need?

Recommendation ID NG147/4 Question What information and support do people with diverticulosis, diverticular disease or acute diverticulitis

Research recommendation Published February 2020

What is the health impact of exposure to individual air pollutants alone or combined with each other in the home?

Recommendation ID NG149/1 Question What is the health impact of exposure to individual air pollutants alone or combined with each other

Research recommendation Published February 2020

What interventions are effective and cost effective at raising awareness of the health risks of damp and mould in the home?

Recommendation ID NG149/5 Question What interventions are effective and cost effective at raising awareness of the health risks of damp

Research recommendation Published February 2020

What are the risk factors for diverticulosis progressing to diverticular disease?

Recommendation ID NG147/6 Question What are the risk factors for diverticulosis progressing to diverticular disease? Any explanatory

Research recommendation Published February 2020

Can risk of contrast-induced acute kidney injury be stratified by eGFR thresholds?

Recommendation ID NG148/1 Question Can risk of contrast-induced acute kidney injury be stratified by eGFR thresholds? Any explanatory

Research recommendation Published February 2020

The committee recommended studies to collect data on the rates of cancelled CT scans, whether cancelled appointments are filled and the effect on patients' experience before and after the introduction of point-of-care (POC) creatinine devices to radiology departments.

Recommendation ID DG37/3 Question The committee recommended studies to collect data on the rates of cancelled CT scans, whether cancelled

Research recommendation Published February 2020

The committee recommended that a suitable risk factor screening tool for identifying risk of PC‑AKI for use across the NHS in people presenting for an outpatient CT scan with contrast agent is developed or an existing tool is validated.

Recommendation ID DG37/2 Question The committee recommended that a suitable risk factor screening tool for identifying risk of PC‑AKI for

Research recommendation Published February 2020

The committee recommended further research on the incidence and effect of post-contrast acute kidney injury (PC‑AKI) in people with eGFR less than 30 ml/min/1.73 m2.

Recommendation ID DG37/1 Question The committee recommended further research on the incidence and effect of post-contrast acute kidney

Research recommendation Published February 2020

What is the effectiveness, cost effectiveness and acceptability of social prescribing for carers?

Recommendation ID NG150/5 Question What is the effectiveness, cost effectiveness and acceptability of social prescribing for carers?

Research recommendation Published February 2020

What is the effectiveness, cost effectiveness and acceptability of carer passport schemes?

Recommendation ID NG150/4 Question What is the effectiveness, cost effectiveness and acceptability of carer passport schemes? Any

Research recommendation Published February 2020

What is the clinical and cost effectiveness of percutaneous thermal ablation for benign thyroid nodules?

Recommendation ID NG145/9 Question What is the clinical and cost effectiveness of percutaneous thermal ablation for benign thyroid nodules

Research recommendation Published February 2020

What is the clinical and cost effectiveness of antibiotics for the management of acute diverticulitis in primary care?

Recommendation ID NG147/1 Question What is the clinical and cost effectiveness of antibiotics for the management of acute diverticulitis

Research recommendation Published February 2020

What is the clinical and cost effectiveness of a block and replace regimen compared with a titration regimen of antithyroid drugs for Graves' disease?

Recommendation ID NG145/8 Question What is the clinical and cost effectiveness of a block and replace regimen compared with a titration

Research recommendation Published February 2020

What is the clinical and cost effectiveness of different durations of antithyroid drug regimens for people with T3 thyrotoxicosis due to Graves' disease?

Recommendation ID NG145/6 Question What is the clinical and cost effectiveness of different durations of antithyroid drug regimens for

Research recommendation Published February 2020

Are there subgroups of people with Graves' disease who have a particularly good response to antithyroid drugs?

Recommendation ID NG145/3 Question Are there subgroups of people with Graves' disease who have a particularly good response to antithyroid

Research recommendation Published February 2020

What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the home?

Recommendation ID NG149/3 Question What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the

Research recommendation Published February 2020

What interventions are effective and cost effective in supporting return to work, in all workplaces including micro-, small- and medium-sized organisations, after long-term sickness absence in the UK?

Recommendation ID NG146/1 Question What interventions are effective and cost effective in supporting return to work, in all workplaces

Research recommendation Published February 2020

For people with common mental health conditions, what interventions are effective and cost effective in reducing long-term sickness absence and supporting return to work in the UK?

Recommendation ID NG146/3 Question For people with common mental health conditions, what interventions are effective and cost effective

Research recommendation Published February 2020

What interventions are effective and cost effective in supporting return to work after recurrent short-term sickness absence in the UK?

Recommendation ID NG146/2 Question What interventions are effective and cost effective in supporting return to work after recurrent short-term

Research recommendation Published February 2020

For people with common mental health conditions, what interventions are effective and cost effective in reducing recurrent short-term sickness absence and supporting return to work in the UK?

Recommendation ID NG146/4 Question For people with common mental health conditions, what interventions are effective and cost effective

Research recommendation Published February 2020

What is the effectiveness and safety of sacral nerve stimulation and transanal irrigation compared to symptomatic treatment for people with major low anterior resection syndrome?

Recommendation ID NG151/2 Question What is the effectiveness and safety of sacral nerve stimulation and transanal irrigation compared to

Research recommendation Published February 2020

What is the most clinically and cost-effective treatment for diverticular disease?

Recommendation ID NG147/3 Question What is the most clinically and cost-effective treatment for diverticular disease? Any explanatory

Research recommendation Published February 2020

What is the clinical and cost effectiveness of levothyroxine for people under 65 with symptomatic subclinical hypothyroidism?

Recommendation ID NG145/7 Question What is the clinical and cost effectiveness of levothyroxine for people under 65 with symptomatic subclinical

Research recommendation Published February 2020

What is the long-term clinical and cost effectiveness, including safety, of radioactive iodine for hyperthyroidism?

Recommendation ID NG145/4 Question What is the long-term clinical and cost effectiveness, including safety, of radioactive iodine for hyperthyroidism

Research recommendation Published February 2020