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Perinatal palliative care:- What impact does timely perinatal palliative care have on the experience of bereaved parents?

Recommendation ID NG61/2 Question Perinatal palliative care:- What impact does timely perinatal palliative care have on the experience of

Research recommendation Published February 2017

Managing communication difficulties in children with cerebral palsy:- What is the clinical and cost effectiveness of interventions for managing communication difficulties in children with cerebral palsy?

Recommendation ID NG62/2 Question Managing communication difficulties in children with cerebral palsy:- What is the clinical and cost effectiveness

Research recommendation Published February 2017

Association between treating infections in pregnancy and rates of cerebral palsy:- What is the association between different antibiotic regimes to treat genito-urinary and respiratory tract infections in pregnant women and subsequent rates of cerebral palsy in children?

Recommendation ID NG62/4 Question Association between treating infections in pregnancy and rates of cerebral palsy:- What is the association

Research recommendation Published February 2017

Effectiveness and cost effectiveness of drug misuse prevention interventions for groups vulnerable to drug misuse:- What is the effectiveness and cost effectiveness of drug misuse prevention interventions for groups vulnerable to drug misuse in the UK?

Recommendation ID NG64/3 Question Effectiveness and cost effectiveness of drug misuse prevention interventions for groups vulnerable to

Research recommendation Published May 2017

Biological therapies for peripheral spondyloarthritis:- What is the effectiveness and cost effectiveness of biological DMARDs in people with persistent peripheral spondyloarthritis (excluding psoriatic arthritis) or undifferentiated spondyloarthritis?

Recommendation ID NG65/5 Question Biological therapies for peripheral spondyloarthritis:- What is the effectiveness and cost effectiveness

Research recommendation Published May 2017

Referral criteria for people with suspected axial spondyloarthritis:- What are the optimal referral criteria for people with suspected axial spondyloarthritis?

Recommendation ID NG65/1 Question Referral criteria for people with suspected axial spondyloarthritis:- What are the optimal referral criteria

Research recommendation Published May 2017

Cost effectiveness:- What is the cost effectiveness of interventions to prevent infection and promote the appropriate use of antimicrobials?

Recommendation ID NG63/1 Question Cost effectiveness:- What is the cost effectiveness of interventions to prevent infection and promote

Research recommendation Published February 2017

Identification of factors associated with suicide:- What factors are associated with suicide attempts and completed suicides?

Recommendation ID NG66/6 Question Identification of factors associated with suicide:- What factors are associated with suicide attempts

Research recommendation Published May 2017

Use of image- and performance-enhancing drugs:- What are the most effective and cost effective interventions to prevent and reduce the use of image- and performance-enhancing drugs?

Recommendation ID NG64/6 Question Use of image- and performance-enhancing drugs:- What are the most effective and cost effective interventions

Research recommendation Published May 2017

What are the most effective and cost-effective interventions to maintain and improve the health and wellbeing of older employees?

Recommendation ID NG13/5 Question What are the most effective and cost-effective interventions to maintain and improve the health and wellbeing

Research recommendation Published November 2016

What are the most effective and cost-effective interventions to help older employees plan and prepare for retirement?

Recommendation ID NG13/7 Question What are the most effective and cost-effective interventions to help older employees plan and prepare

Research recommendation Published November 2016

What are the most effective and cost-effective interventions to help older employees stay in or re-enter work? For example, to overcome the problems of a change in job specification?

Recommendation ID NG13/6 Question What are the most effective and cost-effective interventions to help older employees stay in or re-enter

Research recommendation Published November 2016

Long-term consequences of drug use:- What are the long-term consequences of drug use?

Recommendation ID NG64/1 Question Long-term consequences of drug use:- What are the long-term consequences of drug use? Any explanatory

Research recommendation Published May 2017

What are the most effective and cost-effective interventions to challenge stereotypes and change employers' and workforce attitudes towards older employees?

Recommendation ID NG13/8 Question What are the most effective and cost-effective interventions to challenge stereotypes and change employers'

Research recommendation Published November 2016

Promoting health and wellbeing:- What is the most effective method for delivering health promotion activities and who should lead them (peers or professionals)?

Recommendation ID NG57/3 Question Promoting health and wellbeing:- What is the most effective method for delivering health promotion activities

Research recommendation Published February 2017

Needs assessment:- In the UK, how prevalent is coexisting severe mental illness with substance misuse and what are the physical health, social care, housing or other support needs of people with this diagnosis?

Recommendation ID NG58/1 Question Needs assessment:- In the UK, how prevalent is coexisting severe mental illness with substance misuse

Research recommendation Published February 2017

Radiofrequency denervation:- What is the clinical and cost effectiveness of radiofrequency denervation for chronic low back pain in the long term?

Recommendation ID NG59/3 Question Radiofrequency denervation:- What is the clinical and cost effectiveness of radiofrequency denervation

Research recommendation Published February 2017

Pharmacological therapies:- What is the clinical and cost effectiveness of benzodiazepines for the acute management of low back pain?

Recommendation ID NG59/1 Question Pharmacological therapies:- What is the clinical and cost effectiveness of benzodiazepines for the acute

Research recommendation Published February 2017

NICE encourages further research into single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) for treating morbid obesity, particularly research examining long-term outcomes. NICE may update the guidance on publication of further evidence.

Recommendation ID IPG569/1 Question NICE encourages further research into single-anastomosis duodeno-ileal bypass with sleeve gastrectomy

Research recommendation Published February 2017

NICE concluded that the cost consequences of using HumiGard in abdominal surgery are very uncertain, and that further research is needed on resource use.

Recommendation ID MTG31/2 Question NICE concluded that the cost consequences of using HumiGard in abdominal surgery are very uncertain,

Research recommendation Published April 2017

NICE encourages further research into epiduroscopic lumbar discectomy through the sacral hiatus for sciatica and may update the guidance on publication of further evidence. Research studies should include details of patient selection, complications and long-term results.

Recommendation ID IPG570/1 Question NICE encourages further research into epiduroscopic lumbar discectomy through the sacral hiatus for

Research recommendation Published February 2017

Further research is recommended on alternative postpartum testing strategies that do not include cord blood typing of all babies born to rhesus-D (D) negative women.

Recommendation ID DG25/1 Question Further research is recommended on alternative postpartum testing strategies that do not include cord

Research recommendation Published February 2017

Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does enhanced developmental support and surveillance improve outcomes for the parents and carers of children born preterm?

Recommendation ID NG72/5 Question Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does

Research recommendation Published October 2018

Trials that evaluate utility values (using generic preference-based measures) in children and young people with severe psoriasis are needed to better inform future cost–utility analyses.

Recommendation ID TA455/1 Question Trials that evaluate utility values (using generic preference-based measures) in children and young people

Research recommendation Published October 2018

Rapid eye movement sleep behaviour disorder treatment:- What is the best first-line treatment for rapid eye movement sleep behaviour disorder (RBD) in people with Parkinson's disease?

Recommendation ID NG71/4 Question Rapid eye movement sleep behaviour disorder treatment:- What is the best first-line treatment for rapid

Research recommendation Published October 2018

Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared with atypical antipsychotic drugs for treating psychotic symptoms (particularly hallucinations and delusions) associated with Parkinson's disease?

Recommendation ID NG71/3 Question Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared

Research recommendation Published October 2018

Physiotherapy:- Does physiotherapy started early in the course of Parkinson's disease, as opposed to after motor symptom onset, confer benefits in terms of delaying symptom onset and/or reducing severity?

Recommendation ID NG71/5 Question Physiotherapy:- Does physiotherapy started early in the course of Parkinson's disease, as opposed to after

Research recommendation Published October 2018

Vegetation and street trees:- What factors influence how vegetation and street trees affect urban air quality?

Recommendation ID NG70/1 Question Vegetation and street trees:- What factors influence how vegetation and street trees affect urban air

Research recommendation Published October 2018

Telematics:- How can information about driving style gathered from telematics devices and other technologies (such as apps or in-car global positioning systems) be used to reduce individual fuel consumption and vehicle emissions?

Recommendation ID NG70/4 Question Telematics:- How can information about driving style gathered from telematics devices and other technologies (such

Research recommendation Published October 2018

Promoting a shift to zero- and low-emission travel:- What methods are effective and cost effective at promoting a shift to zero- and low-emission modes of travel, including active travel?

Recommendation ID NG70/2 Question Promoting a shift to zero- and low-emission travel:- What methods are effective and cost effective at

Research recommendation Published October 2018