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NICE during the pre-election period

As a public body, NICE is required to follow civil service principles on communicating during the lead up to the general election.

News Published November 2019 Last updated November 2019

How giving a committee voice to people with a learning disability added value to NICE quality standards

Chris Bird, Quality Standards Programme Manager, tells us how NICE developed the latest learning disability quality standards

News Published October 2019 Last updated October 2019

NICE to support new valuation study for England for EQ-5D-5L questionnaire

Study will measure public’s preference for different health states

News Published October 2019 Last updated October 2019

What is the clinical and cost effectiveness, post treatment and at longer-term follow‑up, of behavioural activation compared with other psychological therapies in children aged 5 to 11 years and young people aged 12 to 18 years with mild or moderate to severe depression?

Recommendation ID NG134/5 Question What is the clinical and cost effectiveness, post treatment and at longer-term follow‑up, of behavioural

Research recommendation Published October 2019

What is the clinical utility of bone turnover markers in the diagnosis and management of primary hyperparathyroidism?

Recommendation ID NG132/1 Question What is the clinical utility of bone turnover markers in the diagnosis and management of primary...

Research recommendation Published October 2019

What is the prognostic value of different risk stratification methods for people with locally advanced prostate cancer?

Recommendation ID NG131/7 Question What is the prognostic value of different risk stratification methods for people with locally advanced

Research recommendation Published October 2019

What is the most clinically and cost-effective pathway for diagnosing clinically significant prostate cancer?

Recommendation ID NG131/3 Question What is the most clinically and cost-effective pathway for diagnosing clinically significant prostate

Research recommendation Published October 2019

How effective are education-based alcohol prevention interventions (universal or targeted) for children and young people aged 11 to 25 with SEND in full-time education?

Recommendation ID NG135/5 Question How effective are education-based alcohol prevention interventions (universal or targeted) for children

Research recommendation Published October 2019

What is the most clinically and cost-effective pathway for excluding the clinically significant progression of cancer in people with low- to intermediate-risk prostate cancer?

Recommendation ID NG131/4 Question What is the most clinically and cost-effective pathway for excluding the clinically significant progression

Research recommendation Published October 2019

At what gestation should treatment with prophylactic vaginal progesterone for the prevention of preterm birth be started and stopped?

Recommendation ID NG25/7 Question At what gestation should treatment with prophylactic vaginal progesterone for the prevention of preterm

Research recommendation Published October 2019

Does progesterone reduce the risk of preterm birth in women who have a short cervix (cervical length of 25 mm or less), but do not have other risk factors for preterm birth?

Recommendation ID NG25/6 Question Does progesterone reduce the risk of preterm birth in women who have a short cervix (cervical length of

Research recommendation Published October 2019

Does progesterone reduce the risk of preterm birth in women who have risk factors for preterm birth, but do not have a short cervix (cervical length of more than 25 mm)?

Recommendation ID NG25/5 Question Does progesterone reduce the risk of preterm birth in women who have risk factors for preterm birth, but

Research recommendation Published October 2019

What is the best and most cost-effective management strategy for people whose first surgery for primary hyperparathyroidism is not successful?

Recommendation ID NG132/2 Question What is the best and most cost-effective management strategy for people whose first surgery for primary

Research recommendation Published October 2019

What are the optimal management strategies for primary hyperparathyroidism during pregnancy?

Recommendation ID NG132/4 Question What are the optimal management strategies for primary hyperparathyroidism during pregnancy? Any

Research recommendation Published October 2019

What is the clinical and cost effectiveness, post-treatment and at longer-term follow‑up, of psychological therapies in children aged 5 to 11 years with mild or moderate to severe depression?

Recommendation ID NG134/1 Question What is the clinical and cost effectiveness, post-treatment and at longer-term follow‑up, of psychological

Research recommendation Published October 2019

What methods and techniques help secondary schools and providers to effectively engage with parents and carers as part of a whole-school approach to promote and support alcohol education?

Recommendation ID NG135/6 Question What methods and techniques help secondary schools and providers to effectively engage with parents and

Research recommendation Published October 2019

The Committee considered that rigorous data collection is needed on the life-extending benefits of lenalidomide when used in people with multiple myeloma who have received two or more prior therapies.

Recommendation ID TA171/1 Question The Committee considered that rigorous data collection is needed on the life-extending benefits of lenalidomide

Research recommendation Published October 2019

What are the long-term outcomes of different management strategies for primary hyperparathyroidism? Which strategies are most cost effective?

Recommendation ID NG132/3 Question What are the long-term outcomes of different management strategies for primary hyperparathyroidism? Which

Research recommendation Published October 2019

What is the natural history of people with a Likert score on MRI of less than 3 without biopsy at long-term follow‑up?

Recommendation ID NG131/5 Question What is the natural history of people with a Likert score on MRI of less than 3 without biopsy at long-term

Research recommendation Published October 2019

What is the optimal regimen for general anaesthesia for women having surgical abortion?

Recommendation ID NG140/7 Question What is the optimal regimen for general anaesthesia for women having surgical abortion? Any explanatory

Research recommendation Published November 2019

What local anaesthetic techniques are most effective for women having surgical abortion?

Recommendation ID NG140/5 Question What local anaesthetic techniques are most effective for women having surgical abortion? Any explanatory

Research recommendation Published November 2019

What is the optimal antibiotic prophylaxis regimen for women who are having a surgical abortion?

Recommendation ID NG140/1 Question What is the optimal antibiotic prophylaxis regimen for women who are having a surgical abortion?

Research recommendation Published November 2019

Should women having a surgical abortion up to and including 10+0 weeks' gestation have anti-D prophylaxis if they are RhD (or D) negative?

Recommendation ID NG140/3 Question Should women having a surgical abortion up to and including 10+0 weeks' gestation have anti-D prophylaxis

Research recommendation Published November 2019

Which automated blood pressure monitors are suitable for people with hypertension and atrial fibrillation?

Recommendation ID NG136/1 Question Which automated blood pressure monitors are suitable for people with hypertension and atrial fibrillation

Research recommendation Published November 2019

What is the optimum blood pressure target for people aged over 80 with treated primary hypertension?

Recommendation ID NG136/3 Question What is the optimum blood pressure target for people aged over 80 with treated primary hypertension?

Research recommendation Published November 2019

What are the most effective and acceptable methods of cervical priming before dilatation and evacuation after 16+0 weeks' gestation?

Recommendation ID NG140/2 Question What are the most effective and acceptable methods of cervical priming before dilatation and evacuation

Research recommendation Published November 2019

Apart from culture, what other diagnostic tests or combinations of tests are effective inestablishing an accurate diagnosis of active respiratory TB in children and young people withsuspected active TB?

Recommendation ID NG33/2 Question Apart from culture, what other diagnostic tests or combinations of tests are effective inestablishing

Research recommendation Published November 2019

The evidence on cardiac contractility modulation device implantation for heart failure raises no major safety concerns. However, the evidence on efficacy is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG655 Question The evidence on cardiac contractility modulation device implantation for heart failure raises no major

Research recommendation Published November 2019

Current evidence on the safety and efficacy of low-energy contact X‑ray brachytherapy (the Papillon technique) for locally advanced rectal cancer is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG659/1 Question Current evidence on the safety and efficacy of low-energy contact X‑ray brachytherapy (the Papillon

Research recommendation Published November 2019

Current evidence on the safety and efficacy of implant insertion for prominent ears is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG660/1 Question Current evidence on the safety and efficacy of implant insertion for prominent ears is inadequate in

Research recommendation Published November 2019

Evidence on the safety and efficacy of high-intensity focused ultrasound for glaucoma is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research.

Recommendation ID IPG661/1 Question Evidence on the safety and efficacy of high-intensity focused ultrasound for glaucoma is inadequate

Research recommendation Published November 2019

Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe emphysema is inadequate in quantity and quality. Therefore the procedure should only be used in the context of research.

Recommendation ID IPG652/1 Question Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe

Research recommendation Published November 2019

What is the utility of routine cardiovascular evaluation for asymptomatic people with FH?

Recommendation ID CG71/6 Question What is the utility of routine cardiovascular evaluation for asymptomatic people with FH? Any explanatory

Research recommendation Published November 2019

When is it safe to stop contact casting in the treatment of acute Charcot arthropathy?

Recommendation ID NG19/12 Question When is it safe to stop contact casting in the treatment of acute Charcot arthropathy? Any explanatory

Research recommendation Published November 2019

Which risk stratification tools can be used to predict the likelihood of Charcot arthropathy?

Recommendation ID NG19/11 Question Which risk stratification tools can be used to predict the likelihood of Charcot arthropathy? Any

Research recommendation Published November 2019

What is the effectiveness and cost effectiveness of a trial of hydrolysed formula in formula‑fed infants with frequent regurgitation associated with marked distress?

Recommendation ID NG1/2 Question What is the effectiveness and cost effectiveness of a trial of hydrolysed formula in formula‑fed infants

Research recommendation Published November 2019