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Molecular testing strategies for Lynch syndrome in people with colorectal cancer (DG27)

Evidence-based recommendations on immunohistochemistry/microsatellite instability testing to guide tests for Lynch syndrome in people with colon cancer

Diagnostics guidance Published February 2017

Rapid tests for group A streptococcal infections in people with a sore throat (DG38)

Evidence-based recommendations on rapid tests for group A streptococcal (strep A) infections in people aged 5 and over with a sore throat

Diagnostics guidance Published November 2019

Adjunctive colposcopy technologies for assessing suspected cervical abnormalities: the DYSIS colposcope with DYSISmap and the ZedScan I (DG32)

Evidence-based recommendations on DYSIS colposcope with DYSISmap and ZedScan I for assessing suspected cervical abnormalities in people having colposcopy

Diagnostics guidance Published April 2018

Biomarker tests to help diagnose preterm labour in women with intact membranes (DG33)

Evidence-based recommendations on biomarker tests (Actim Partus, PartoSure, Rapid fFN 10Q Cassette) to diagnose preterm labour in women with intact membranes

Diagnostics guidance Published July 2018

Multiple frequency bioimpedance devices to guide fluid management in people with chronic kidney disease having dialysis (DG29)

Evidence-based recommendations on multi frequency bioimpedance devices to guide fluid management for people with chronic kidney disease having dialysis

Diagnostics guidance Published June 2017

Integrated multiplex PCR tests for identifying gastrointestinal pathogens in people with suspected gastroenteritis (xTAG Gastrointestinal Pathogen Panel, FilmArray GI Panel and Faecal Pathogens B assay) (DG26)

Evidence-based recommendations on integrated multiplex polymerase chain tests for identifying gastrointestinal pathogens in suspected gastroenteritis

Diagnostics guidance Published January 2017

New generation cardiac CT scanners (Aquilion ONE, Brilliance iCT, Discovery CT750 HD and Somatom Definition Flash) for cardiac imaging in people with suspected or known coronary artery disease in whom imaging is difficult with earlier generation CT scanners (DG3)

Evidence-based recommendations on new generation computed tomography (CT) scanners for cardiac imaging for suspected or known coronary artery disease

Diagnostics guidance Published January 2012 Last updated July 2017

Virtual chromoendoscopy to assess colorectal polyps during colonoscopy (DG28)

Evidence-based recommendations on virtual chromoendoscopy (VCE) using NBI, FICE or i-scan to assess colorectal polyps of 5 mm or less during colonoscopy

Diagnostics guidance Published May 2017

Therapeutic monitoring of TNF-alpha inhibitors in rheumatoid arthritis (DG36)

Evidence-based recommendations on enzyme-linked immunosorbent assay (ELISA) tests for therapeutic monitoring of TNF-alpha inhibitors in rheumatoid arthritis

Diagnostics guidance Published July 2019

Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer (DG34)

Evidence-based recommendations on tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer

Diagnostics guidance Published December 2018

Quantitative faecal immunochemical tests to guide referral for colorectal cancer in primary care (DG30)

Evidence-based recommendations on quantitative faecal immunochemical tests (OC Sensor, HM-JACKarc and FOB Gold) to guide GP referral for colorectal cancer

Diagnostics guidance Published July 2017

Atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers (the CoaguChek XS system) (DG14)

Evidence-based recommendations on point-of-care coagulometers (the CoaguChek XS system) to self-monitor blood clotting

Diagnostics guidance Published September 2014 Last updated December 2017

Point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast (DG37)

Evidence-based recommendations on point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast

Diagnostics guidance Published November 2019

Tests in secondary care to identify people at high risk of ovarian cancer (DG31)

Evidence-based recommendations on tests (IOTA ADNEX, Overa, RMI I, ROMA, IOTA Simple Rules) in secondary care to identify people at high risk of ovarian cancer

Diagnostics guidance Published November 2017

Lead-I ECG devices for detecting symptomatic atrial fibrillation using single time point testing in primary care (DG35)

Evidence-based recommendations on lead-I ECG devices for detecting symptomatic atrial fibrillation using single time point testing in primary care

Diagnostics guidance Published May 2019

Platelet-rich plasma injections for knee osteoarthritis (IPG637)

Evidence-based recommendations on platelet-rich plasma injections for knee osteoarthritis in adults (deterioration of the articular cartilage and menisci)

Interventional procedures guidance Published January 2019

Low-level laser therapy for preventing or treating oral mucositis caused by radiotherapy or chemotherapy (IPG615)

Evidence-based recommendations on low-level laser therapy for preventing or treating oral mucositis caused by radiotherapy or chemotherapy

Interventional procedures guidance Published May 2018

Artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure (IPG602)

Evidence-based recommendations on artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure

Interventional procedures guidance Published December 2017

Subcutaneous implantable cardioverter defibrillator insertion for preventing sudden cardiac death (IPG603)

Evidence-based recommendations on subcutaneous implantable cardioverter defibrillator insertion for preventing sudden cardiac death

Interventional procedures guidance Published December 2017

Transvaginal mesh repair of anterior or posterior vaginal wall prolapse (IPG599)

Evidence-based recommendations on transvaginal mesh repair of anterior or posterior vaginal wall prolapse

Interventional procedures guidance Published December 2017

Low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures (IPG623)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of delayed-union and non-union fractures

Interventional procedures guidance Published July 2018

Low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk of non-healing (IPG622)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of fresh fractures at high risk of non-healing

Interventional procedures guidance Published July 2018

Low-intensity pulsed ultrasound to promote healing of fresh fractures at low risk of non-healing (IPG621)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of fresh fractures at low risk of non-healing in adults

Interventional procedures guidance Published July 2018

Transaxial interbody lumbosacral fusion for severe chronic low back pain (IPG620)

Evidence-based recommendations on transaxial interbody lumbosacral fusion for low back pain in adults

Interventional procedures guidance Published July 2018

Superior capsular augmentation for massive rotator cuff tears (IPG619)

Evidence-based recommendations on superior capsular augmentation for massive rotator cuff (shoulder) tears

Interventional procedures guidance Published July 2018

Laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina (IPG608)

Evidence-based recommendations on laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina

Interventional procedures guidance Published March 2018

Mosaicplasty for symptomatic articular cartilage defects of the knee (IPG607)

Evidence-based recommendations on mosaicplasty for symptomatic articular cartilage defects of the knee (osteochondral autologous transfer mosaicplasty)

Interventional procedures guidance Published March 2018

Unilateral MRI-guided focused ultrasound thalamotomy for moderate to severe tremor in Parkinson's disease (IPG606)

Evidence-based recommendations on unilateral MRI-guided focused ultrasound thalamotomy for moderate to severe tremor in Parkinson’s disease in adults

Interventional procedures guidance Published February 2018

Aortic valve reconstruction with processed bovine pericardium (IPG604)

Evidence-based recommendations on aortic valve reconstruction with processed bovine pericardium (using new valve made from chemically treated cow pericardium)

Interventional procedures guidance Published February 2018

Endobronchial valve insertion to reduce lung volume in emphysema (IPG600)

Evidence-based recommendations on endobronchial valve insertion to reduce lung volume in emphysema

Interventional procedures guidance Published December 2017

Transcutaneous microwave ablation for severe primary axillary hyperhidrosis (IPG601)

Evidence-based recommendations on transcutaneous microwave ablation for severe primary axillary hyperhidrosis (excessive sweating) in adults

Interventional procedures guidance Published December 2017

Sutureless aortic valve replacement for aortic stenosis (IPG624)

Evidence-based recommendations on sutureless aortic valve replacement for aortic stenosis in adults

Interventional procedures guidance Published August 2018

Superior rectal artery embolisation for haemorrhoids (IPG627)

Evidence-based recommendations on superior rectal artery embolisation for haemorrhoids in adults

Interventional procedures guidance Published August 2018

Leadless cardiac pacemaker implantation for bradyarrhythmias (IPG626)

Evidence-based recommendations on leadless cardiac pacemaker implantation for bradyarrhythmias (an inserted device to help the heart beat at a normal rate)

Interventional procedures guidance Published August 2018

Transurethral water jet ablation for lower urinary tract symptoms caused by benign prostatic hyperplasia (IPG629)

Evidence-based recommendations on transurethral water jet ablation for lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)

Interventional procedures guidance Published September 2018

Intravesical microwave hyperthermia and chemotherapy for non-muscle-invasive bladder cancer (IPG628)

Evidence-based recommendations on intravesical microwave hyperthermia and chemotherapy for non-muscle-invasive bladder cancer

Interventional procedures guidance Published September 2018

Midcarpal hemiarthroplasty for wrist arthritis (IPG663)

Evidence-based recommendations on midcarpal hemiarthroplasty (using a metal implant to create an artificial wrist joint) for wrist arthritis in adults

Interventional procedures guidance Published October 2019

Radiofrequency treatment for haemorrhoids (IPG589)

Evidence-based recommendations on radiofrequency treatment for haemorrhoids in adults

Interventional procedures guidance Published August 2017

Liposuction for chronic lymphoedema (IPG588)

Evidence-based recommendations on liposuction for chronic lymphoedema in adults to remove build-up of fluid and excess fat tissue in limbs

Interventional procedures guidance Published August 2017

Biodegradable spacer insertion to reduce rectal toxicity during radiotherapy for prostate cancer (IPG590)

Evidence-based recommendations on biodegradable spacer insertion (gel or balloon) to reduce rectal toxicity during radiotherapy for prostate cancer in adults

Interventional procedures guidance Published August 2017

Extracranial to intracranial bypass for intracranial atherosclerosis (IPG596)

Evidence-based recommendations on extracranial to intracranial bypass for intracranial atherosclerosis

Interventional procedures guidance Published November 2017

Total distal radioulnar joint replacement for symptomatic joint instability or arthritis (IPG595)

Evidence-based recommendations on total distal radioulnar joint replacement for symptomatic joint instability or arthritis in adults

Interventional procedures guidance Published November 2017

High-intensity focused ultrasound for symptomatic breast fibroadenoma (IPG592)

Evidence-based recommendations on high-intensity focused ultrasound for symptomatic breast fibroadenoma (benign/non-cancerous lumps in the breast)

Interventional procedures guidance Published September 2017

Ab externo canaloplasty for primary open-angle glaucoma (IPG591)

Evidence-based recommendations on ab externo canaloplasty (widening eye’s main draining canal) for primary open-angle glaucoma (damaged optic nerve)

Interventional procedures guidance Published September 2017

Intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure caused by high spinal cord injuries (IPG594)

Evidence-based recommendations on intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure caused by high spinal cord injuries

Interventional procedures guidance Published September 2017

Intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure caused by motor neurone disease (IPG593)

Evidence-based recommendations on intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure in people with motor neurone disease

Interventional procedures guidance Published September 2017

Microinvasive subconjunctival insertion of a trans-scleral gelatin stent for primary open-angle glaucoma (IPG612)

Evidence-based recommendations on microinvasive subconjunctival insertion of a trans-scleral gelatin stent (tube) for primary open-angle glaucoma in adults

Interventional procedures guidance Published April 2018

Prostate artery embolisation for lower urinary tract symptoms caused by benign prostatic hyperplasia (IPG611)

Evidence-based recommendations on prostate artery embolisation for lower urinary tract symptoms caused by benign prostatic hyperplasia in adults

Interventional procedures guidance Published April 2018

Nerve transfer to partially restore upper limb function in tetraplegia (IPG610)

Evidence-based recommendations on nerve transfer to partially restore upper limb function in people with tetraplegia (quadriplegia; paralysis of arms and legs)

Interventional procedures guidance Published April 2018

Robot-assisted kidney transplant (IPG609)

Evidence-based recommendations on robot-assisted kidney transplant in adults

Interventional procedures guidance Published April 2018