Evidence-based recommendations on cerliponase alfa (Brineura) for treating neuronal ceroid lipofuscinosis type 2 (CLN2) in children
Evidence-based recommendations on voretigene neparvovec (Luxturna) for RPE65-mediated inherited retinal dystrophies (confirmed biallelic RPE65 gene mutations)
Evidence-based recommendations on patisiran (Onpattro) for treating hereditary transthyretin amyloidosis in adults with stage 1 and stage 2 polyneuropathy
Evidence-based recommendations on inotersen (Tegsedi) for stage 1 and stage 2 polyneuropathy in adults with hereditary transthyretin amyloidosis
Evidence-based recommendations on burosumab (Crysvita) for treating X-linked hypophosphataemia (XLH) in children and young people
Evidence-based recommendation on Strimvelis for adenosine deaminase deficiency–severe combined immunodeficiency (ADA–SCID)
Evidence-based recommendations on asfotase alfa (Strensiq) for treating paediatric-onset hypophosphatasia in adults and children
Evidence-based recommendations on eliglustat (Cerdelga) for treating type 1 Gaucher disease in adults
Evidence-based recommendations on migalastat (Galafold) for treating Fabry disease in people over 16
Evidence-based recommendations on irreversible electroporation (IRE) for treating pancreatic cancer
Evidence-based recommendations on minimally invasive sacroiliac joint fusion surgery for chronic sacroiliac pain (lower back pain)
Evidence-based recommendations on sacrocolpopexy with hysterectomy (removal of womb) using mesh to repair uterine prolapse (prolapsed womb)
Evidence-based recommendations on extraurethral (non-circumferential) retropubic adjustable compression devices for stress urinary incontinence in women
Evidence-based recommendations on trabecular stent bypass microsurgery for open-angle glaucoma (damaged optic nerve)
Evidence-based recommendations on lateral interbody fusion in the lumbar spine for low back pain
Evidence-based recommendations on hypoglossal nerve stimulation for moderate to severe obstructive sleep apnoea in adults
Evidence-based recommendations on processed nerve allografts (specially treated nerves) to repair peripheral nerve discontinuities (bridge gaps)
Evidence-based recommendations on extracranial to intracranial bypass for intracranial atherosclerosis
Evidence-based recommendations on total distal radioulnar joint replacement for symptomatic joint instability or arthritis in adults
Evidence-based recommendations on intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure caused by high spinal cord injuries
Evidence-based recommendations on intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure in people with motor neurone disease
Evidence-based recommendations on high-intensity focused ultrasound for symptomatic breast fibroadenoma (benign/non-cancerous lumps in the breast)
Evidence-based recommendations on ab externo canaloplasty (widening eye’s main draining canal) for primary open-angle glaucoma (damaged optic nerve)
Evidence-based recommendations on biodegradable spacer insertion (gel or balloon) to reduce rectal toxicity during radiotherapy for prostate cancer in adults
Evidence-based recommendations on radiofrequency treatment for haemorrhoids in adults
Evidence-based recommendations on liposuction for chronic lymphoedema in adults to remove build-up of fluid and excess fat tissue in limbs
Evidence-based recommendations on transcatheter aortic valve implantation (TAVI) for aortic stenosis
Evidence-based recommendations on laparoscopic insertion of a magnetic titanium ring for gastro-oesophageal reflux disease (GORD) in adults
Evidence-based recommendations on uterine suspension using mesh (including sacrohysteropexy) to repair uterine prolapse in women
Evidence-based recommendations on sacropolpopexy using mesh to repair vaginal vault prolapse in women
Evidence-based recommendations on infracoccygeal sacropexy using mesh to repair uterine (womb) prolapse in women
Evidence-based recommendations on infracoccygeal sacropexy using mesh to repair vaginal vault prolapse in women
Evidence-based recommendations on endoscopic full thickness removal of non-lifting colonic polyps (colonic adenomas/growths)
Evidence-based recommendations on percutaneous balloon valvuloplasty for fetal critical aortic stenosis
Evidence-based recommendations on nerve transfer to partially restore upper limb function in people with tetraplegia (quadriplegia; paralysis of arms and legs)
Evidence-based recommendations on laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina
Evidence-based recommendations on mosaicplasty for symptomatic articular cartilage defects of the knee (osteochondral autologous transfer mosaicplasty)
Evidence-based recommendations on unilateral MRI-guided focused ultrasound thalamotomy for moderate to severe tremor in Parkinson’s disease in adults
Evidence-based recommendations on aortic valve reconstruction with processed bovine pericardium (using new valve made from chemically treated cow pericardium)
Evidence-based recommendations on subcutaneous implantable cardioverter defibrillator insertion for preventing sudden cardiac death
Evidence-based recommendations on artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure
Evidence-based recommendations on transcutaneous microwave ablation for severe primary axillary hyperhidrosis (excessive sweating) in adults
Evidence-based recommendations on endobronchial valve insertion to reduce lung volume in emphysema
Evidence-based recommendations on transvaginal mesh repair of anterior or posterior vaginal wall prolapse
Evidence-based recommendations on selective internal radiation therapy (SIRT) for unresectable primary intrahepatic cholangiocarcinoma in adults
Evidence-based recommendations on transurethral water jet ablation for lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)
Evidence-based recommendations on intravesical microwave hyperthermia and chemotherapy for non-muscle-invasive bladder cancer
Evidence-based recommendations on superior rectal artery embolisation for haemorrhoids in adults
Evidence-based recommendations on leadless cardiac pacemaker implantation for bradyarrhythmias (an inserted device to help the heart beat at a normal rate)
Evidence-based recommendations on transurethral water vapour ablation for lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)