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Olaparib for maintenance treatment of relapsed platinum-sensitive ovarian, fallopian tube or peritoneal cancer (TA620)

Evidence-based recommendations on olaparib (Lynparza) for relapsed platinum-sensitive ovarian, fallopian tube or primary peritoneal cancer in adults with a

Technology appraisal guidance Published January 2020

Palbociclib with fulvestrant for treating hormone receptor-positive, HER2-negative, advanced breast cancer (TA619)

Evidence-based recommendations on palbociclib (Ibrance) with fulvestrant for hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer

Technology appraisal guidance Published January 2020

Atezolizumab with carboplatin and nab-paclitaxel for untreated advanced non-squamous non-small-cell lung cancer (terminated appraisal) (TA618)

NICE is unable to make a recommendation about the use in the NHS of atezolizumab (Tecentriq) with carboplatin and nab-paclitaxel for untreated advanced NSCLC

Technology appraisal guidance Published January 2020

EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing (MTG12)

Evidence-based recommendations on the EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing

Medical technologies guidance Published January 2013 Last updated October 2019

Virtual Touch Quantification to diagnose and monitor liver fibrosis in chronic hepatitis B and C (MTG27)

Evidence-based recommendations on Virtual Touch Quantification for diagnosing and monitoring liver fibrosis in chronic Hepatitis B and C

Medical technologies guidance Published September 2015 Last updated January 2020

The 3M Tegaderm CHG IV securement dressing for central venous and arterial catheter insertion sites (MTG25)

Evidence-based recommendations on the 3M Tegaderm CHG IV securement dressing for central venous and arterial catheter insertion sites

Medical technologies guidance Published July 2015 Last updated September 2019

gammaCore for cluster headache (MTG46)

Evidence-based recommendations on gammaCore for cluster headache

Medical technologies guidance Published December 2019

Episcissors-60 for mediolateral episiotomy (MTG47)

Evidence-based recommendations on Episcissors-60 for mediolateral episiotomy

Medical technologies guidance Published February 2020

SepsiTest assay for rapidly identifying bloodstream bacteria and fungi (DG20)

Evidence-based recommendations on the SepsiTest assay for rapidly identifying bloodstream bacteria and fungi

Diagnostics guidance Published February 2016 Last updated February 2020

Point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast (DG37)

Evidence-based recommendations on point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast

Diagnostics guidance Published November 2019

Rapid tests for group A streptococcal infections in people with a sore throat (DG38)

Evidence-based recommendations on rapid tests for group A streptococcal (strep A) infections in people aged 5 and over with a sore throat

Diagnostics guidance Published November 2019

Implant insertion for prominent ears (IPG660)

Evidence-based recommendations on implant insertion for prominent ears in children, young people and adults

Interventional procedures guidance Published September 2019

High-intensity focused ultrasound for glaucoma (IPG661)

Evidence-based recommendations on high-intensity focused ultrasound for glaucoma in adults. This involves using high-intensity ultrasound to destroy a small

Interventional procedures guidance Published September 2019

Bioprosthetic plug insertion for anal fistula (IPG662)

Evidence-based recommendations on bioprosthetic plug insertion for anal fistula in adults. This involves putting a plug into the fistula and stitching it in

Interventional procedures guidance Published September 2019

Midcarpal hemiarthroplasty for wrist arthritis (IPG663)

Evidence-based recommendations on midcarpal hemiarthroplasty (using a metal implant to create an artificial wrist joint) for wrist arthritis in adults

Interventional procedures guidance Published October 2019

Irreversible electroporation for primary liver cancer (IPG664)

Evidence-based recommendations on irreversible electroporation for primary liver cancer in adults

Interventional procedures guidance Published November 2019

Balloon dilation for chronic eustachian tube dysfunction (IPG665)

Evidence-based recommendations on balloon dilation for chronic eustachian tube dysfunction in adults and children

Interventional procedures guidance Published December 2019

Reducing the risk of transmission of Creutzfeldt–Jakob disease (CJD) from surgical instruments used for interventional procedures on high-risk tissues (IPG666)

Evidence-based recommendations on reducing the risk of Creutzfeldt–Jakob disease (CJD) transmission from surgical instruments used for interventional procedures

Interventional procedures guidance Published January 2020

Fetoscopic prenatal repair for open neural tube defects in the fetus (IPG667)

Evidence-based recommendations on fetoscopic prenatal repair of open neural tube defects in the fetus

Interventional procedures guidance Published January 2020

Open prenatal repair for open neural tube defects in the fetus (IPG668)

Evidence-based recommendations on open prenatal repair of open neural tube defects in the fetus

Interventional procedures guidance Published January 2020

SuperNO2VA for the relief of upper airway obstruction in people with obstructive sleep apnoea (MIB190)

Advice on the use of SuperNO2VA for the relief of upper airway obstruction in people with obstructive sleep apnoea to aid local decision making

Medtech innovation briefing Published September 2019

UroShield for preventing catheter-associated urinary tract infections (MIB191)

Advice on the use of UroShield for preventing catheter-associated urinary tract infections (CAUTI) to aid local decision making

Medtech innovation briefing Published September 2019

InterDry for intertrigo (MIB192)

Advice on the use of InterDry for intertrigo (inflammatory skin rash) to aid local decision making

Medtech innovation briefing Published September 2019

Alpha-Stim AID for anxiety (MIB193)

Advice on the use of Alpha-Stim AID for anxiety to aid local decision making

Medtech innovation briefing Published September 2019

superDimension Navigation System to help diagnostic sampling of peripheral lung lesions (MIB194)

Advice on the use of superDimension Navigation System to help diagnostic sampling of peripheral lung lesions to aid local decision making

Medtech innovation briefing Published October 2019

MR-proADM test for use with clinical deterioration scores in cases of suspected infection (MIB195)

Advice on the use of MR-proADM test for use with clinical deterioration scores in cases of suspected infection to aid local decision making

Medtech innovation briefing Published October 2019

DyeVert for reducing contrast media in coronary and peripheral angiography (MIB196)

NICE has developed a medtech innovation briefing (MIB) on DyeVert for reducing contrast media in coronary and peripheral angiography

Medtech innovation briefing Published November 2019

The V.A.C. Veraflo Therapy system for infected wounds (MIB189)

Advice on the use of the V.A.C. Veraflo Therapy system for infected wounds to aid local decision making

Medtech innovation briefing Published September 2019

Leukomed Sorbact for preventing surgical site infection (MIB197)

Advice on the use of Leukomed Sorbact for preventing surgical site infection (SSI) to aid local decision making

Medtech innovation briefing Published November 2019

AmnioSense for unexplained vaginal wetness in pregnancy (MIB198)

Advice on the use of AmnioSense (non-invasive diagnostic pad/liner) for unexplained vaginal wetness in pregnancy to aid local decision making

Medtech innovation briefing Published November 2019

Optowire for measuring fractional flow reserve (MIB199)

Advice on the use of Optowire (sterile, fibreoptic-based, disposable guide wire) for measuring fractional flow reserve (FFR) to aid local decision making

Medtech innovation briefing Published December 2019

PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection (MIB200)

Advice on the use of PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection to aid local decision making

Medtech innovation briefing Published December 2019

Plus Sutures for preventing surgical site infection (MIB204)

NICE has developed a medtech innovation briefing (MIB) on Plus Sutures for preventing surgical site infection

Medtech innovation briefing Published February 2020

National Early Warning Score systems that alert to deteriorating adult patients in hospital (MIB205)

NICE has developed a medtech innovation briefing (MIB) on National Early Warning Score systems that alert to deteriorating adult patients in hospital

Medtech innovation briefing Published February 2020

eXroid for internal haemorrhoids (MIB201)

Advice on the use of eXroid, using direct current electrotherapy to blood vessels of internal haemorrhoid to shrink haemorrhoids, to aid local decision making

Medtech innovation briefing Published December 2019

LQD Spray for treating acute and chronic wounds (MIB202)

Advice on the use of LQD Spray (spray-on dressing containing modified biopolymer chitosan FH02) for treating acute/chronic wounds to aid local decision making

Medtech innovation briefing Published December 2019

PulmoVista 500 for monitoring ventilation in critical care (MIB203)

Advice on the use of PulmoVista 500 for monitoring ventilation in critical care to aid local decision making

Medtech innovation briefing Published December 2019

Wound care products (KTT14)

This document summarises the evidence base on wound care products . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2015 Last updated September 2019

Anticoagulants, including direct-acting oral anticoagulants (DOACs) (KTT16)

This key therapeutic topic has been reincluded in the September 2019 update of medicines optimisation: key therapeutic topics. This document summarises the evidence base on anticoagulants , including direct-acting oral anticoagulants (DOACs). It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published February 2016 Last updated September 2019

Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI (KTT17)

This document summarises the evidence base on the use of medicines in people with or at increased risk of acute kidney injury . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published February 2016 Last updated September 2019

Multimorbidity and polypharmacy (KTT18)

This document summarises the evidence base on multimorbidity and polypharmacy . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2017 Last updated September 2019

Shared decision making (KTT23)

This document summarises the evidence base on shared decision making . It is a key therapeutic topic that has been identified to support Medicines Optimisation. It is not formal NICE guidance .

Key therapeutic topic Published March 2019 Last updated September 2019

Suicide prevention: optimising medicines and reducing access to medicines as a means of suicide (KTT24)

This document summarises the evidence base on suicide prevention: optimising medicines and reducing access to medicines as a means of suicide . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published March 2019 Last updated September 2019

Lipid-modifying drugs (KTT3)

This key therapeutic topic has been reincluded in the September 2019 update of medicines optimisation: key therapeutic topics. This document summarises the evidence base on lipid-modifying drugs. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2015 Last updated September 2019

Psychotropic medicines in people with learning disabilities whose behaviour challenges (KTT19)

This document summarises the evidence base on psychotropic medicines in people with learning disabilities whose behaviour challenges . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2017 Last updated September 2019

Safer insulin prescribing (KTT20)

This document summarises the evidence base on safer insulin prescribing . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2017 Last updated September 2019

Medicines optimisation in chronic pain (KTT21)

This document summarises the evidence base on medicines optimisation in chronic pain . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2017 Last updated September 2019

Chemotherapy dose standardisation (KTT22)

This document summarises the evidence base on chemotherapy dose standardisation . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published February 2018 Last updated September 2019

Asthma: medicines safety priorities (KTT5)

This document summarises the evidence base on asthma: medicines safety priorities . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2015 Last updated September 2019

Hypnotics (KTT6)

This document summarises the evidence base on hypnotics . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2015 Last updated September 2019