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NICE during the pre-election period

As a public body, NICE is required to follow civil service principles on communicating during the lead up to the general election.

News Published November 2019 Last updated November 2019

How giving a committee voice to people with a learning disability added value to NICE quality standards

Chris Bird, Quality Standards Programme Manager, tells us how NICE developed the latest learning disability quality standards

News Published October 2019 Last updated October 2019

NICE to support new valuation study for England for EQ-5D-5L questionnaire

Study will measure public’s preference for different health states

News Published October 2019 Last updated October 2019

How does the timing and frequency of ultrasound examination affect diagnosis and outcomes of early pregnancy complications, including women's experience and cost effectiveness?

Recommendation ID NG126/1 Question How does the timing and frequency of ultrasound examination affect diagnosis and outcomes of early pregnancy

Research recommendation Published August 2019

What are the costs associated with best supportive care?

Recommendation ID TA575/1 Question What are the costs associated with best supportive care? Any explanatory notes(if applicable)

Research recommendation Published August 2019

What is the best technique for delivering surfactant in a minimally invasive manner?

Recommendation ID NG124/2 Question What is the best technique for delivering surfactant in a minimally invasive manner? Any explanatory

Research recommendation Published August 2019

Does caesarean section protect against cerebral haemorrhage in women with a history of subarachnoid haemorrhage or cerebrovascular malformation?

Recommendation ID NG121/1 Question Does caesarean section protect against cerebral haemorrhage in women with a history of subarachnoid haemorrhage

Research recommendation Published August 2019

What clinical features and laboratory investigations can be used to better stratify risk for women in labour with signs of sepsis (including fever and tachycardia)?

Recommendation ID NG121/4 Question What clinical features and laboratory investigations can be used to better stratify risk for women in

Research recommendation Published August 2019

Are progesterone or progestogens effective in treating threatened miscarriage?

Recommendation ID NG136/3 Question Are progesterone or progestogens effective in treating threatened miscarriage? Any explanatory notes(if

Research recommendation Published August 2019

What is the clinical and cost effectiveness of intermittent auscultation compared with continuous cardiotocography for women in labour who have had a previous caesarean section?

Recommendation ID NG121/5 Question What is the clinical and cost effectiveness of intermittent auscultation compared with continuous cardiotocography

Research recommendation Published August 2019

What is the most effective combination of an analgesic with a neuromuscular blocker, or an analgesic with an anaesthetic agent, for premedication in preterm babies requiring elective or semi-elective intubation?

Recommendation ID NG124/5 Question What is the most effective combination of an analgesic with a neuromuscular blocker, or an analgesic

Research recommendation Published August 2019

Does targeting higher oxygen saturations of 92% to 97% in preterm babies lead to improved survival without significant complications?

Recommendation ID NG124/4 Question Does targeting higher oxygen saturations of 92% to 97% in preterm babies lead to improved survival without...

Research recommendation Published August 2019

Is obesity an independent risk factor for perinatal morbidity and mortality?

Recommendation ID NG121/3 Question Is obesity an independent risk factor for perinatal morbidity and mortality? Any explanatory notes(if

Research recommendation Published August 2019

What is the effectiveness of high-pressure non-invasive positive pressure ventilation (NIPPV) compared with continuous positive airways pressure (CPAP) flow driver as the primary mode of ventilation?

Recommendation ID NG124/1 Question What is the effectiveness of high-pressure non-invasive positive pressure ventilation (NIPPV) compared

Research recommendation Published August 2019

Does the use of ultrasound of the lumbar spine improve siting of regional anaesthetic needles in pregnant women with a BMI over 30 kg/m2 at the booking appointment?

Recommendation ID NG121/2 Question Does the use of ultrasound of the lumbar spine improve siting of regional anaesthetic needles in pregnant

Research recommendation Published August 2019

What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination with a chlorhexidine body wash in the whole population?

Recommendation ID NG125/1 Question What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination

Research recommendation Published August 2019

Is the use of chlorhexidine body wash associated with increased antimicrobial resistance?

Recommendation ID NG125/2 Question Is the use of chlorhexidine body wash associated with increased antimicrobial resistance? Any explanatory

Research recommendation Published August 2019

In women with confirmed miscarriage, does the type of management strategy (expectant, medical and surgical) impact on women's experience, including psychological and emotional outcomes?

Recommendation ID NG126/4 Question In women with confirmed miscarriage, does the type of management strategy (expectant, medical and surgical)

Research recommendation Published August 2019

What is the effectiveness of diuretics compared with placebo in preventing bronchopulmonary dysplasia (BPD) in preterm babies on respiratory support?

Recommendation ID NG124/3 Question What is the effectiveness of diuretics compared with placebo in preventing bronchopulmonary dysplasia

Research recommendation Published August 2019

In women with ectopic pregnancy, does the type of intervention impact on women's experience, including psychological and emotional outcomes?

Recommendation ID NG126/5 Question In women with ectopic pregnancy, does the type of intervention impact on women's experience, including

Research recommendation Published August 2019

Which patient groups, contamination groups and which layers gain the most benefit from the use of triclosan-coated or triclosan-impregnated sutures?

Recommendation ID NG125/5 Question Which patient groups, contamination groups and which layers gain the most benefit from the use of triclosan-coated

Research recommendation Published August 2019

What are the cost associated with best supportive care?

Recommendation ID TA574/1 Question What are the cost associated with best supportive care? Any explanatory notes(if applicable)

Research recommendation Published August 2019

What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in the prevention of surgical site infection when applied to the skin before incision?

Recommendation ID NG125/3 Question What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in

Research recommendation Published August 2019

Is the application of antiseptics and antibiotics in the operative field before wound closure, clinically and cost effective in reducing surgical site infection rates?

Recommendation ID NG125/4 Question Is the application of antiseptics and antibiotics in the operative field before wound closure, clinically

Research recommendation Published August 2019

What is the most effective surgical management for women with both stress urinary incontinence and pelvic organ prolapse, including the sequence of interventions?

Recommendation ID NG123/7 Question What is the most effective surgical management for women with both stress urinary incontinence and pelvic

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of stereotactic ablative radiotherapy (SABR) compared with surgery (for example, sublobar, wedge resection, lobectomy) for people with non-small-cell lung cancer (stage I and IIA) in whom surgery is suitable?

Recommendation ID NG122/2 Question What is the effectiveness and cost effectiveness of stereotactic ablative radiotherapy (SABR) compared

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of routinely performing contrast-enhanced brain CT at the time of initial diagnosis and/or staging CT?

Recommendation ID NG122/3 Question What is the effectiveness and cost effectiveness of routinely performing contrast-enhanced brain CT at

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of prophylactic cranial irradiation compared with routine MRI follow-up in people with extensive-stage small-cell lung cancer without brain metastases?

Recommendation ID NG122/4 Question What is the effectiveness and cost effectiveness of prophylactic cranial irradiation compared with routine

Research recommendation Published June 2019

What are the long-term outcomes, including patient satisfaction, from the use of pessaries compared with surgery for pelvic organ prolapse in women?

Recommendation ID NG123/4 Question What are the long-term outcomes, including patient satisfaction, from the use of pessaries compared with

Research recommendation Published June 2019

What is the effectiveness of pain management for women who present with chronic pain 3 months after mesh surgery for stress urinary incontinence or pelvic organ prolapse?

Recommendation ID NG123/8 Question What is the effectiveness of pain management for women who present with chronic pain 3 months after mesh

Research recommendation Published June 2019

What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary incontinence and pelvic organ prolapse in women?

Recommendation ID NG123/5 Question What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary incontinence

Research recommendation Published June 2019

What is the long-term effectiveness of bladder wall injection with botulinum toxin type A for overactive bladder in women?

Recommendation ID NG123/6 Question What is the long-term effectiveness of bladder wall injection with botulinum toxin type A for overactive

Research recommendation Published June 2019

What is the effectiveness and cost effectiveness of immunotherapy in people with stage IIIA-N2 non-small-cell lung cancer following multimodality treatment including surgery?

Recommendation ID NG122/1 Question What is the effectiveness and cost effectiveness of immunotherapy in people with stage IIIA-N2 non-small-cell

Research recommendation Published June 2019

What is the effectiveness of colpocleisis compared with sacrospinous fixation for pelvic organ prolapse in elderly women?

Recommendation ID NG123/2 Question What is the effectiveness of colpocleisis compared with sacrospinous fixation for pelvic organ prolapse

Research recommendation Published June 2019

What is the effectiveness of ultrasound-guided visualisation compared with clinical assessment to identify complications after mesh surgery for stress urinary incontinence or pelvic organ prolapse in women?

Recommendation ID NG123/3 Question What is the effectiveness of ultrasound-guided visualisation compared with clinical assessment to identify

Research recommendation Published June 2019

What is the effectiveness and safety of anticholinergic medicines for overactive bladder in older women?

Recommendation ID NG123/1 Question What is the effectiveness and safety of anticholinergic medicines for overactive bladder in older women

Research recommendation Published June 2019

What is the utility of routine cardiovascular evaluation for asymptomatic people with FH?

Recommendation ID CG71/6 Question What is the utility of routine cardiovascular evaluation for asymptomatic people with FH? Any explanatory

Research recommendation Published November 2019

When is it safe to stop contact casting in the treatment of acute Charcot arthropathy?

Recommendation ID NG19/12 Question When is it safe to stop contact casting in the treatment of acute Charcot arthropathy? Any explanatory

Research recommendation Published November 2019

Which risk stratification tools can be used to predict the likelihood of Charcot arthropathy?

Recommendation ID NG19/11 Question Which risk stratification tools can be used to predict the likelihood of Charcot arthropathy? Any

Research recommendation Published November 2019

What is the effectiveness and cost effectiveness of a trial of hydrolysed formula in formula‑fed infants with frequent regurgitation associated with marked distress?

Recommendation ID NG1/2 Question What is the effectiveness and cost effectiveness of a trial of hydrolysed formula in formula‑fed infants

Research recommendation Published November 2019

What is the malformation rate and longer term neurodevelopmental outcome of children born to mothers who have taken AEDs during pregnancy?

Recommendation ID CG137/5 Question What is the malformation rate and longer term neurodevelopmental outcome of children born to mothers

Research recommendation Published November 2019

What is the clinical effectiveness of maggot debridement therapy in the debridement of diabetic foot ulcers?

Recommendation ID NG19/10 Question What is the clinical effectiveness of maggot debridement therapy in the debridement of diabetic foot

Research recommendation Published November 2019

What is the clinical effectiveness of negative pressure wound therapy in the treatment of diabetic foot ulcers?

Recommendation ID NG19/9 Question What is the clinical effectiveness of negative pressure wound therapy in the treatment of diabetic foot

Research recommendation Published November 2019

What is the clinical effectiveness of different dressing types in treating diabetic foot problems?

Recommendation ID NG19/5 Question What is the clinical effectiveness of different dressing types in treating diabetic foot problems?

Research recommendation Published November 2019

What is the clinical effectiveness of double-dose PPIs in people with severe erosive reflux disease (Los Angeles classification grade C/D or Savary–Miller grade 3/4): to reduce severe oesophagitis to control symptoms as maintenance therapy?

Recommendation ID CG184/3 Question What is the clinical effectiveness of double-dose PPIs in people with severe erosive reflux disease (Los

Research recommendation Published November 2019

Which of the electronic information-sharing systems perform best for the care of people approaching the end of their life?

Recommendation ID NG142/2 Question Which of the electronic information-sharing systems perform best for the care of people approaching the

Research recommendation Published November 2019