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Adjunctive colposcopy technologies for assessing suspected cervical abnormalities: the DYSIS colposcope with DYSISmap and the ZedScan I (DG32)

Evidence-based recommendations on DYSIS colposcope with DYSISmap and ZedScan I for assessing suspected cervical abnormalities in people having colposcopy

Diagnostics guidance Published April 2018

Tests in secondary care to identify people at high risk of ovarian cancer (DG31)

Evidence-based recommendations on tests (IOTA ADNEX, Overa, RMI I, ROMA, IOTA Simple Rules) in secondary care to identify people at high risk of ovarian cancer

Diagnostics guidance Published November 2017

Quantitative faecal immunochemical tests to guide referral for colorectal cancer in primary care (DG30)

Evidence-based recommendations on quantitative faecal immunochemical tests (OC Sensor, HM-JACKarc and FOB Gold) to guide GP referral for colorectal cancer

Diagnostics guidance Published July 2017

New generation cardiac CT scanners (Aquilion ONE, Brilliance iCT, Discovery CT750 HD and Somatom Definition Flash) for cardiac imaging in people with suspected or known coronary artery disease in whom imaging is difficult with earlier generation CT scanners (DG3)

Evidence-based recommendations on new generation computed tomography (CT) scanners for cardiac imaging for suspected or known coronary artery disease

Diagnostics guidance Published January 2012 Last updated July 2017

Multiple frequency bioimpedance devices to guide fluid management in people with chronic kidney disease having dialysis (DG29)

Evidence-based recommendations on multi frequency bioimpedance devices to guide fluid management for people with chronic kidney disease having dialysis

Diagnostics guidance Published June 2017

Virtual chromoendoscopy to assess colorectal polyps during colonoscopy (DG28)

Evidence-based recommendations on virtual chromoendoscopy (VCE) using NBI, FICE or i-scan to assess colorectal polyps of 5 mm or less during colonoscopy

Diagnostics guidance Published May 2017

Molecular testing strategies for Lynch syndrome in people with colorectal cancer (DG27)

Evidence-based recommendations on immunohistochemistry/microsatellite instability testing to guide tests for Lynch syndrome in people with colon cancer

Diagnostics guidance Published February 2017

Integrated multiplex PCR tests for identifying gastrointestinal pathogens in people with suspected gastroenteritis (xTAG Gastrointestinal Pathogen Panel, FilmArray GI Panel and Faecal Pathogens B assay) (DG26)

Evidence-based recommendations on integrated multiplex polymerase chain tests for identifying gastrointestinal pathogens in suspected gastroenteritis

Diagnostics guidance Published January 2017

High-throughput non-invasive prenatal testing for fetal RHD genotype (DG25)

Evidence-based recommendations on high-throughput non-invasive prenatal testing (NIPT) for fetal RHD genotype

Diagnostics guidance Published November 2016

ImmunoCAP ISAC 112 and Microtest for multiplex allergen testing (DG24)

Evidence-based recommendations on ImmunoCAP ISAC 112 and Microtest for multiplex allergen testing to diagnose allergy and predict the risk of allergic reaction

Diagnostics guidance Published May 2016

PlGF-based testing to help diagnose suspected pre-eclampsia (Triage PlGF test, Elecsys immunoassay sFlt-1/PlGF ratio, DELFIA Xpress PlGF 1-2-3 test, and BRAHMS sFlt-1 Kryptor/BRAHMS PlGF plus Kryptor PE ratio) (DG23)

Evidence-based recommendations on PlGF-based testing to help diagnose suspected pre-eclampsia

Diagnostics guidance Published May 2016

Therapeutic monitoring of TNF-alpha inhibitors in Crohn's disease (LISA-TRACKER ELISA kits, IDKmonitor ELISA kits, and Promonitor ELISA kits) (DG22)

Evidence-based recommendations on therapeutic monitoring of TNF-alpha inhibitors in Crohn’s disease

Diagnostics guidance Published February 2016

Integrated sensor-augmented pump therapy systems for managing blood glucose levels in type 1 diabetes (the MiniMed Paradigm Veo system and the Vibe and G4 PLATINUM CGM system) (DG21)

Evidence-based recommendations on the MiniMed Paradigm Veo and Vibe and G4 PLATINUM CGM sensor-augmented pump therapy systems for type 1 diabetes

Diagnostics guidance Published February 2016

Tests for rapidly identifying bloodstream bacteria and fungi (LightCycler SeptiFast Test MGRADE, SepsiTest and IRIDICA BAC BSI assay) (DG20)

Evidence-based recommendations on the LightCycler SeptiFast Test MGRADE, SepsiTest and IRIDICA BAC BSI assay for identifying bloodstream bacteria and fungi

Diagnostics guidance Published February 2016

VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesions (DG19)

Evidence-based recommendations on VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesions

Diagnostics guidance Published November 2015

Procalcitonin testing for diagnosing and monitoring sepsis (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay) (DG18)

Evidence-based recommendations on procalcitonin testing for diagnosing and monitoring sepsis (AVIDA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive..

Diagnostics guidance Published October 2015

Myocardial infarction (acute): Early rule out using high-sensitivity troponin tests (Elecsys Troponin T high-sensitive, ARCHITECT STAT High Sensitive Troponin-I and AccuTnI+3 assays) (DG15)

Evidence-based recommendations on high-sensitivity troponin tests for the early rule-out of acute myocardial infarction (AMI)

Diagnostics guidance Published October 2014

Atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers (the CoaguChek XS system) (DG14)

Evidence-based recommendations on point-of-care coagulometers (the CoaguChek XS system) to self-monitor blood clotting

Diagnostics guidance Published September 2014 Last updated December 2017

Measuring fractional exhaled nitric oxide concentration in asthma: NIOX MINO, NIOX VERO and NObreath (DG12)

Evidence-based recommendations on the NIOX MINO, NIOX VERO and Nobreath devices to measure fractional exhaled nitric oxide concentration in asthma

Diagnostics guidance Published April 2014

Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel (DG11)

Evidence-based recommendations on faecal calprotectin diagnostic tests for inflammatory diseases of the bowel

Diagnostics guidance Published October 2013

The EOS 2D/3D imaging system (DG1)

Evidence-based recommendations on the EOS 2D/3D imaging system for radiological examinations

Diagnostics guidance Published October 2011

SeHCAT (tauroselcholic [75 selenium] acid) for the investigation of diarrhoea due to bile acid malabsorption in people with diarrhoea-predominant irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection (DG7)

Evidence-based recommendations on SeHCAT (tauroselcholic [75 selenium] acid) for investigating diarrhoea due to bile acid malabsorption (BAM)

Diagnostics guidance Published November 2012

Depth of anaesthesia monitors – Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M (DG6)

Evidence-based recommendations on the Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M depth of anaesthesia monitors

Diagnostics guidance Published November 2012

SonoVue (sulphur hexafluoride microbubbles) – contrast agent for contrast-enhanced ultrasound imaging of the liver (DG5)

Evidence-based recommendations on theSonoVue (sulphur hexafluoride microbubbles) contrast agent for contrast-enhanced ultrasound imaging of the liver

Diagnostics guidance Published August 2012

Therapeutic monitoring of TNF-alpha inhibitors in rheumatoid arthritis (DG36)

Evidence-based recommendations on enzyme-linked immunosorbent assay (ELISA) tests for therapeutic monitoring of TNF-alpha inhibitors in rheumatoid arthritis

Diagnostics guidance Published July 2019

Rapid tests for group A streptococcal infections in people with a sore throat (DG38)

Evidence-based recommendations on rapid tests for group A streptococcal (strep A) infections in people aged 5 and over with a sore throat

Diagnostics guidance Published November 2019

Detecting, managing and monitoring haemostasis: viscoelastometric point‑of‑care testing (ROTEM, TEG and Sonoclot systems) (DG13)

Evidence-based recommendations on viscoelastometric point-of-care testing (ROTEM, TEG and Sonoclot systems) to detect, manage and monitor haemostasis

Diagnostics guidance Published August 2014

Intraoperative tests (RD‑100i OSNA system and Metasin test) for detecting sentinel lymph node metastases in breast cancer (DG8)

Evidence-based recommendations on the RD-100i OSNA system and Metasin test for detecting sentinel lymph node metastases in breast cancer

Diagnostics guidance Published August 2013

EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (DG9)

Evidence-based recommendations on EGFR-TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (NSCLC)

Diagnostics guidance Published August 2013

Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment (DG16)

Evidence-based recommendations on the My5-FU assay for guiding dose adjustment for fluorouracil chemotherapy

Diagnostics guidance Published December 2014

Point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast (DG37)

Evidence-based recommendations on point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast

Diagnostics guidance Published November 2019

Therapeutic hypothermia with intracorporeal temperature monitoring for hypoxic perinatal brain injury (IPG347)

Evidence-based recommendations on therapeutic hypothermia with intracorporeal temperature monitoring for treating hypoxic perinatal brain injury

Interventional procedures guidance Published May 2010

Mini-incision surgery for total knee replacement (IPG345)

Evidence-based recommendations on mini-incision surgery for total knee replacement

Interventional procedures guidance Published May 2010

Epithelial radiofrequency ablation for Barrett's oesophagus (IPG344)

Evidence-based recommendations on epithelial radiofrequency ablation for treating Barrett's oesophagus

Interventional procedures guidance Published May 2010

Haemorrhoidal artery ligation (IPG342)

Evidence-based recommendations on haemorrhoidal artery ligation for treating haemorrhoids (piles)

Interventional procedures guidance Published May 2010

Prosthetic intervertebral disc replacement in the cervical spine (IPG341)

Evidence-based recommendations on prosthetic intervertebral disc replacement in the cervical spine for treating degenerative cervical disc disease

Interventional procedures guidance Published May 2010

Macular translocation with 360° retinotomy for wet age-related macular degeneration (IPG340)

Evidence-based recommendations on macular translocation with 360° retinotomy for treating wet (exudative) age-related macular degeneration (AMD)

Interventional procedures guidance Published May 2010

Circular stapled haemorrhoidectomy (IPG34)

Evidence-based recommendations on circular stapled haemorrhoidectomy for treating internal haemorrhoids

Interventional procedures guidance Published December 2003

Limited macular translocation for wet age-related macular degeneration (IPG339)

Evidence-based recommendations on limited macular translocation for treating wet (exudative) age-related macular degeneration (AMD)

Interventional procedures guidance Published May 2010

Laparoscopic radical hysterectomy for early stage cervical cancer (IPG338)

Evidence-based recommendations on laparoscopic radical hysterectomy for treating early stage cervical cancer

Interventional procedures guidance Published May 2010

Endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions (IPG337)

Evidence-based recommendations on endobronchial ultrasound-guided transbronchial biopsy for treating peripheral lung lesions (pulmonary nodules)

Interventional procedures guidance Published March 2010

Transcatheter endovascular closure of perimembranous ventricular septal defect (IPG336)

Evidence-based recommendations on transcatheter endovascular closure of perimembranous ventricular septal defect (VSD) for treating holes in the heart

Interventional procedures guidance Published March 2010

Endoscopic submucosal dissection of lower gastrointestinal lesions (IPG335)

Evidence-based recommendations on endoscopic submucosal dissection of lower gastrointestinal lesions

Interventional procedures guidance Published March 2010

Arteriovenous crossing sheathotomy for branch retinal vein occlusion (IPG334)

Evidence-based recommendations on arteriovenous crossing sheathotomy for treating branch retinal vein occlusion (BRVO, retinal vascular thrombosis)

Interventional procedures guidance Published March 2010

Therapeutic endoscopic division of epidural adhesions (IPG333)

Evidence-based recommendations on therapeutic endoscopic division of epidural adhesions for back or leg pain from adhesions around the spinal nerve roots

Interventional procedures guidance Published February 2010

Surgical correction of hallux valgus using minimal access techniques (IPG332)

Evidence-based recommendations on surgical correction using minimal access techniques for treating hallux valgus (bunions)

Interventional procedures guidance Published February 2010

Cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis (IPG331)

Evidence-based recommendations on cytoreduction surgery and hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis (cancer)

Interventional procedures guidance Published February 2010

Vagus nerve stimulation for treatment-resistant depression (IPG330)

Evidence-based recommendations on vagus nerve stimulation for treatment-resistant depression

Interventional procedures guidance Published December 2009

Endoaortic balloon occlusion for cardiac surgery (IPG261)

Evidence-based recommendations on endoaortic balloon occlusion for heart surgery

Interventional procedures guidance Published May 2008

Interstitial photodynamic therapy for malignant parotid tumours (IPG259)

Evidence-based recommendations on interstitial photodynamic therapy (PDT) for treating malignant parotid tumours

Interventional procedures guidance Published April 2008