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  1. Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment (DG16)

    Evidence-based recommendations on the My5-FU assay for measuring levels of 5-flurouracil (5-FU) in patients having chemotherapy, to help guide changes to the

  2. Obesity: identification, assessment and management (CG189)

    This guideline covers identifying, assessing and managing obesity in children (aged 2 years and over), young people and adults. It aims to improve the use of bariatric surgery and very-low-calorie diets to help people who are obese to reduce their weight.

  3. Telemetric adjustable pulmonary artery banding for pulmonary hypertension in infants with congenital heart defects (IPG505)

    Evidence-based recommendations on telemetric adjustable pulmonary artery banding for treating pulmonary hypertension in infants with congenital heart defects

  4. Insertion of an annular disc implant at lumbar discectomy (IPG506)

    Evidence-based recommendations on inserting an annular disc implant at lumbar discectomy for treating lumbar disc herniation (slipped disc)

  5. Gallstone disease: diagnosis and management (CG188)

    This guideline covers diagnosing and managing gallstone disease in adults. It aims to reduce variation in care by promoting the most effective treatments, and to improve the advice given to people with gallstone disease before and after treatment.

  6. Drug allergy: diagnosis and management (CG183)

    This guideline covers diagnosing and managing drug allergy in all age groups. It aims to make it easier for professionals to tell when someone is having an allergic reaction, by specifying the key signs and patterns to look out for. It also makes recommendations on improving people’s understanding of their drug allergies, and ensuring these are recorded properly in their medical records.

  7. Transient loss of consciousness ('blackouts') in over 16s (CG109)

    This guideline covers assessment, diagnosis and referral for people over 16 who have had a transient loss of consciousness (TLoC; also called a blackout). It aims to improve care for people with TLoC by specifying the most effective assessments and recommending when to refer to a specialist.

  8. Assessing motility of the gastrointestinal tract using a wireless capsule (IPG502)

    Evidence-based recommendations on assessing motility of the gastrointestinal (GI) tract using a wireless capsule to investigate motility disorders

  9. Detecting, managing and monitoring haemostasis: viscoelastometric point‑of‑care testing (ROTEM, TEG and Sonoclot systems) (DG13)

    NICE has assessed 3 viscoelastometric point-of-care testing devices (the ROTEM, TEG and Sonoclot systems), to help the NHS decide whether to use these products

  10. Powered microdebrider turbinoplasty for inferior turbinate hypertrophy (IPG498)

    Evidence-based recommendations on powdered micodebrider turbinoplasty for inferior turbinate hypertrophy (swollen ridges in the nose)

  11. Endoscopic radiofrequency ablation for Barrett's oesophagus with low‑grade dysplasia or no dysplasia (IPG496)

    Evidence-based recommendations on endoscopic radiofrequency ablation for Barrett’s oesophagus with low-grade dysplasia or no dysplasia

  12. Safe staffing for nursing in adult inpatient wards in acute hospitals (SG1)

    This guideline covers organisational and managerial approaches to safe nurse staffing of inpatient wards for people aged 18 and over in acute hospitals. It aims to ensure that patients receive the nursing care they need, regardless of the ward to which they are allocated, the time of the day, or the day of the week.

  13. Endoscopic saphenous vein harvest for coronary artery bypass grafting (IPG494)

    Evidence-based recommendations on endoscopic saphenous vein harvest for coronary artery bypass grafting in coronary artery disease (CAD)

  14. Radiofrequency tissue reduction for turbinate hypertrophy (IPG495)

    Evidence-based recommendations on radiofrequency tissue reduction for turbinate hypertrophy (swollen ridges in the nose that narrow the nasal passage)

  15. Endoscopic thoracic sympathectomy for primary hyperhidrosis of the upper limb (IPG487)

    Evidence-based recommendations on endoscopic thoracic sympathectomy for primary hyperhidrosis (excess sweating) of the upper limb (palm of hand and armpit)

  16. Arthroscopic radiofrequency chondroplasty for discrete chondral defects of the knee (IPG493)

    Evidence-based recommendations on arthroscopic radiofrequency chondroplasty for discrete chondral defects of the articular cartilage in the knee

  17. Pressure ulcers: prevention and management (CG179)

    This guideline covers risk assessment, prevention and treatment in children, young people and adults at risk of, or who have, a pressure ulcer (also known as a bedsore or pressure sore). It aims to reduce the number of pressure ulcers in people admitted to secondary or tertiary care or receiving NHS care in other settings, such as primary and community care and emergency departments.

  18. Measuring fractional exhaled nitric oxide concentration in asthma: NIOX MINO, NIOX VERO and NObreath (DG12)

    Evidence-based recommendations on NIOX MINO, NIOX VERO and NObreath for measuring the amount of exhaled nitric oxide (FeNO) in the breath to help diagnose

  19. Faecal microbiota transplant for recurrent Clostridium difficile infection (IPG485)

    Evidence-based recommendations on faecal microbiota transplant for recurrent Clostridium difficile infection. This involves introducing enteric bacteria from

  20. Transoral carbon dioxide laser surgery for primary treatment of oropharyngeal malignancy (IPG484)

    Evidence-based recommendations on transoral carbon dioxide (CO2) laser surgery for primary treatment of oropharyngeal malignancy (throat cancer)

  21. Psychosis and schizophrenia in adults: prevention and management (CG178)

    This guideline covers recognising and managing psychosis and schizophrenia in adults. It aims to improve care through early recognition and treatment, and by focusing on long-term recovery. It also recommends checking for coexisting health problems and providing support for family members and carers.

  22. Electrochemotherapy for primary basal cell carcinoma and primary squamous cell carcinoma (IPG478)

    Evidence-based recommendations on electrochemotherapy for primary basal cell carcinoma (BCC) and primary squamous cell carcinoma (SCC) (skin cancer)

  23. Endoscopic thoracic sympathectomy for primary facial blushing (IPG480)

    Evidence-based recommendations on endoscopic thoracic sympathectomy (cutting off nerve signals to stop blushing) for primary facial blushing

  24. Optical coherence tomography to guide percutaneous coronary intervention (IPG481)

    Evidence-based recommendations on optical coherence tomography to guide percutaneous coronary intervention (near-infrared light for artery imaging)

  25. Insertion of prostatic urethral lift implants to treat lower urinary tract symptoms secondary to benign prostatic hyperplasia (IPG475)

    Evidence-based recommendations on prostatic urethral lift implants to treat lower tract symptoms secondary to benign prostate hyperplasia (enlarged prostate)

  26. Percutaneous closure of patent foramen ovale to prevent recurrent cerebral embolic events (IPG472)

    Evidence-based recommendations on percutaneous closure of patent foramen ovale (PFO/hole in the heart) to prevent recurrent cerebral embolic events

  27. Ultra-radical (extensive) surgery for advanced ovarian cancer (IPG470)

    Evidence-based recommendations on ultra-radical (extensive) surgery for advanced ovarian cancer (removing cancerous tissue from all organs)

  28. Implantation of a duodenal–jejunal bypass sleeve for managing obesity (IPG471)

    Evidence-based recommendations on the implantation of a duodenal–jejunal bypass sleeve (temporary implant in the gut) for managing obesity

  29. Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel (DG11)

    Evidence-based recommendations on faecal calprotectin tests for distinguishing between inflammatory bowel diseases (such as Crohn’s disease and ulcerative

  30. Photochemical corneal collagen cross‑linkage using riboflavin and ultraviolet A for keratoconus and keratectasia (IPG466)

    Evidence-based recommendations on photochemical corneal collagen cross-linkage using riboflavin and ultraviolet A for keratoconus and keratectasia

  31. Endoscopic radiofrequency ablation for gastro-oesophageal reflux disease (IPG461)

    Evidence-based recommendations on endoscopic radiofrequency ablation for gastro-oesophageal reflux disease (acid reflux/ GORD/GERD)

  32. EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (DG9)

    Evidence-based recommendations on testing for epidermal growth factor receptor tyrosine kinase (EGFR–TK) mutations in untreated, locally advanced or metastatic