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The Juxta CURES adjustable compression system for treating venous leg ulcers (MIB25)

Advice on the use of the Juxta CURES adjustable compression system for treating venous leg ulcers to aid local decision-making

Medtech innovation briefing Published March 2015

The PediGuard for placing pedicle screws in spinal surgery (MIB26)

Advice on the use of the PediGuard for placing pedicle screws in spinal surgery to aid local decision-making

Medtech innovation briefing Published March 2015

Xpert GBS test for the intrapartum detection of group B streptococcus (MIB28)

Advice on the use of the Xpert GBS test for the intrapartum detection of group B streptococcus (GBS) colonisation in pregnant women...

Medtech innovation briefing Published April 2015

LipiFlow thermal pulsation treatment for dry eyes caused by blocked meibomian glands (MIB29)

Advice on the use of the LipiFlow thermal pulsation treatment for dry eyes caused by blocked meibomian glands to aid local decision-making

Medtech innovation briefing Published April 2015

LARS for reconstructing damaged intra-articular cruciate knee ligaments (MIB30)

Advice on the use of the LARS (ligament augmentation and reconstruction system) for reconstructing damaged intra-articular cruciate knee ligaments...

Medtech innovation briefing Published May 2015

Peptest for diagnosing gastro‑oesophageal reflux (MIB31)

Advice on the use of the Peptest for diagnosing gastro-oesophageal reflux disease (GORD) to aid local decision-making

Medtech innovation briefing Published May 2015

BD MAX Enteric Bacterial Panel for identifying pathogens in contagious gastroenteritis (MIB32)

Advice on the use of the BD MAX Enteric Bacterial Panel (EBP) for identifying pathogens in contagious gastroenteritis to aid local decision-making

Medtech innovation briefing Published July 2015

Spiral Flow peripheral vascular graft for treating peripheral arterial disease (MIB34)

Advice on the use of the Spiral Flow peripheral vascular (PV) graft for treating peripheral arterial disease (PAD) to aid local decision-making

Medtech innovation briefing Published July 2015

Thermogard XP for therapeutic hypothermia after cardiac arrest (MIB37)

Advice on the use of the Thermogard XP system for treating therapeutic hypothermia after cardiac arrest to aid local decision-making

Medtech innovation briefing Published September 2015

i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department (MIB38)

Advice on the use of the i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department to aid local decision-making

Medtech innovation briefing Published September 2015

ERBE flexible cryoprobes for bronchoscopic diagnosis and treatment (MIB39)

Advice on the use of ERBE flexible cryoprobes for bronchoscopic diagnosis and treatment to aid local decision-making

Medtech innovation briefing Published September 2015

The RhinoChill intranasal cooling system for reducing temperature after cardiac arrest (MIB4)

Advice on the use of the RhinoChill intranasal cooling system for reducing temperature after cardiac arrest to aid local decision-making

Medtech innovation briefing Published February 2014

PulmoVista 500 for monitoring ventilation in critical care (MIB203)

Advice on the use of PulmoVista 500 for monitoring ventilation in critical care to aid local decision making

Medtech innovation briefing Published December 2019

Plus Sutures for preventing surgical site infection (MIB204)

NICE has developed a medtech innovation briefing (MIB) on Plus Sutures for preventing surgical site infection

Medtech innovation briefing Published February 2020

National Early Warning Score systems that alert to deteriorating adult patients in hospital (MIB205)

NICE has developed a medtech innovation briefing (MIB) on National Early Warning Score systems that alert to deteriorating adult patients in hospital

Medtech innovation briefing Published February 2020

The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system (MIB21)

Advice on the use of The SpyGlass direct visualisation system for diagnostic and therapeutic procedures during endoscopy of the biliary system..

Medtech innovation briefing Published February 2015

Shiley Endotracheal Tube with TaperGuard Cuff for intensive care patients at risk of ventilator‑associated pneumonia (MIB22)

Advice on the use of Shiley Endotracheal Tube with TaperGuard Cuff for patients at risk of ventilator-associated pneumonia to aid local decision-making

Medtech innovation briefing Published March 2015

The Epidrum for aiding access to the epidural space (MIB23)

Advice on the use of the Epidrum for aiding access to the epidural space to aid local decision-making

Medtech innovation briefing Published March 2015

Active B12 assay for diagnosing vitamin B12 deficiency (MIB40)

Advice on the use of the Active B12 assay for diagnosing vitamin B12 deficiency to aid local decision-making

Medtech innovation briefing Published September 2015

PROPATEN heparin-bonded vascular graft for peripheral arterial disease (MIB42)

Advice on the use of the PROPATEN heparin-bonded vascular graft for treating peripheral arterial disease to aid local decision-making

Medtech innovation briefing Published October 2015

ATEC system for vacuum-assisted breast biopsy (MIB43)

Advice on the use of the ATEC system for vacuum-assisted breast biopsy to aid local decision-making

Medtech innovation briefing Published November 2015

AliveCor Heart Monitor and AliveECG app (Kardia Mobile) for detecting atrial fibrillation (MIB35)

Advice on the use of the AliveCor Heart Monitor and AliveECG (Kardia Mobile) app for detecting atrial fibrillation (AF) to aid local decision-making

Medtech innovation briefing Published August 2015

Visensia for early detection of deteriorating vital signs in adults in hospital (MIB36)

Advice on the use of the Visensia for early detection of deteriorating vital signs in adults in hospital to aid local decision-making

Medtech innovation briefing Published August 2015

PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection (MIB200)

Advice on the use of PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection to aid local decision making

Medtech innovation briefing Published December 2019

eXroid for internal haemorrhoids (MIB201)

Advice on the use of eXroid, using direct current electrotherapy to blood vessels of internal haemorrhoid to shrink haemorrhoids, to aid local decision making

Medtech innovation briefing Published December 2019

LQD Spray for treating acute and chronic wounds (MIB202)

Advice on the use of LQD Spray (spray-on dressing containing modified biopolymer chitosan FH02) for treating acute/chronic wounds to aid local decision making

Medtech innovation briefing Published December 2019

The NGAL Test for early diagnosis of acute kidney injury (MIB3)

Advice on the use of the NGAL Test for early diagnosis of acute kidney injury (AKI) to aid local decision-making

Medtech innovation briefing Published February 2014

Biosimilar medicines (KTT15)

The key therapeutic topic biosimilar medicines has been retired from the 2019 update of medicines optimisation: key therapeutic topics. The version published in 2018 is available here for information but it has not been updated since February 2018. Like all the other key therapeutic topics it is not formal NICE guidance .

Key therapeutic topic Published February 2016 Last updated February 2018

Anticoagulants, including direct-acting oral anticoagulants (DOACs) (KTT16)

This key therapeutic topic has been reincluded in the September 2019 update of medicines optimisation: key therapeutic topics. This document summarises the evidence base on anticoagulants , including direct-acting oral anticoagulants (DOACs). It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published February 2016 Last updated September 2019

Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI (KTT17)

This document summarises the evidence base on the use of medicines in people with or at increased risk of acute kidney injury . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published February 2016 Last updated September 2019

Multimorbidity and polypharmacy (KTT18)

This document summarises the evidence base on multimorbidity and polypharmacy . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2017 Last updated September 2019

Type 2 diabetes mellitus: medicines optimisation priorities (KTT12)

This document summarises the evidence base on type 2 diabetes mellitus: medicines optimisation priorities . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2015 Last updated September 2019

Laxatives (KTT1)

The key therapeutic topic laxatives has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance .

Key therapeutic topic Published January 2015

Non-steroidal anti-inflammatory drugs (KTT13)

The key therapeutic topic non-steroidal anti-inflammatory drugs has been retired from the 2019 update of medicines optimisation: key therapeutic topics. The version published in 2018 is available here for information but it has not been updated since February 2018. Like all the other key therapeutic topics it is not formal NICE guidance .

Key therapeutic topic Published January 2015 Last updated February 2018

Minocycline (KTT11)

The key therapeutic topic minocycline has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance .

Key therapeutic topic Published January 2015

Wound care products (KTT14)

This document summarises the evidence base on wound care products . It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance .

Key therapeutic topic Published January 2015 Last updated September 2019

Asthma: fluticasone furoate/vilanterol (Relvar Ellipta) combination inhaler (ESNM34)

Summary of the evidence on the fluticasone furoate/vilanterol (Relvar Ellipta) combination inhaler for asthma to inform local NHS planning and decision-making

Evidence summary Published March 2014

Systemic juvenile idiopathic arthritis: canakinumab (ESNM36)

Summary of the evidence on canakinumab for treating systemic juvenile idiopathic arthritis (JIA) to inform local NHS planning and decision-making

Evidence summary Published March 2014

Partial seizures in children and young people with epilepsy: zonisamide as adjunctive therapy (ESNM37)

Summary of the evidence on zonisamide as adjunctive therapy for partial seizures in children and young people (aged 6–17 years) with epilepsy..

Evidence summary Published March 2014

Induction of labour: misoprostol vaginal delivery system (ESNM38)

Summary of the evidence on the misoprostol vaginal delivery system for induction of labour to inform local NHS planning and decision-making

Evidence summary Published March 2014 Last updated November 2014

Non-Hodgkin's lymphoma: rituximab subcutaneous injection (ESNM46)

Summary of the evidence on rituximab subcutaneous injection for non-Hodgkin's lymphoma in adults to inform local NHS planning and decision-making

Evidence summary Published September 2014

Chronic obstructive pulmonary disease: beclometasone/formoterol (Fostair) (ESNM47)

Summary of the evidence on beclometasone/formoterol (Fostair) for treating chronic obstructive pulmonary disease (COPD)...

Evidence summary Published September 2014

Facial erythema of rosacea: brimonidine tartrate gel (ESNM43)

Summary of the evidence on brimonidine tartrate gel for treating facial erythema of rosacea to inform local NHS planning and decision-making

Evidence summary Published July 2014

Hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus: telavancin (ESNM44)

Summary of the evidence on telavancin (Vibativ) for hospital-acquired pneumonia caused by MRSA to inform local NHS planning and decision-making

Evidence summary Published July 2014

Erectile dysfunction: avanafil (ESNM45)

Summary of the evidence on avanafil for treating erectile dysfunction to inform local NHS planning and decision-making

Evidence summary Published August 2014

Schizophrenia: lurasidone (ESNM48)

Summary of the evidence on lurasidone (Latuda) for schizophrenia in adults aged 18 and over to inform local NHS planning and decision-making

Evidence summary Published September 2014

Chronic obstructive pulmonary disease: umeclidinium/vilanterol combination inhaler (Anoro Ellipta) (ESNM49)

Summary of the evidence on umeclidinium/vilanterol combination inhaler (Anoro Ellipta) for treating chronic obstructive pulmonary disease (COPD)...

Evidence summary Published November 2014

Schizophrenia: aripiprazole prolonged-release suspension for injection (ESNM39)

Summary of the evidence on aripiprazole prolonged-release suspension for injection for schizophrenia to inform local NHS planning and decision-making

Evidence summary Published March 2014

Premature ejaculation: dapoxetine (ESNM40)

Summary of the evidence on dapoxetine for premature ejaculation to inform local NHS planning and decision-making

Evidence summary Published May 2014

Long-acting reversible contraception: levonorgestrel 13.5 mg intrauterine delivery system (ESNM41)

Summary of the evidence on the levonorgestrel intrauterine delivery system (long-acting reversible contraception) to inform local NHS planning...

Evidence summary Published June 2014