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QuikRead go for C-reactive protein testing in primary care (MIB78)

Advice on the use of QuickRead go for C-reactive protein (CRP) testing in primary care to aid local decision-making

Medtech innovation briefing Published September 2016

OSNA for colon cancer staging (MIB77)

Advice on the use of OSNA in vitro diagnostic molecular assay system for staging colon cancer to aid local decision-making

Medtech innovation briefing Published August 2016

Axxent electronic brachytherapy system for early stage breast cancer (MIB76)

Advice on the use of the Axxent electronic brachytherapy system for treating early stage breast cancer to aid local decision-making

Medtech innovation briefing Published August 2016

Stretta System for gastro-oesophageal reflux disease (MIB74)

Advice on the use of Stretta System for gastro-oesophageal reflux disease (GORD)

Medtech innovation briefing Published July 2016

QTUG for assessing falls risk and frailty (MIB73)

Advice on the use of the Quantitative Timed Up and Go (QTUG) to assess mobility, falls risk and frailty during the standard Timed Up and Go (TUG) test to aid…

Medtech innovation briefing Published July 2016

Alair bronchial thermoplasty system for adults with severe difficult to control asthma (MIB71)

Advice on the use of the Alair bronchial thermoplasty system for treating adults with severe, difficult to control asthma to aid local decision-making

Medtech innovation briefing Published July 2016

Mobi-C for cervical disc replacement (MIB70)

Advice on the use of Mobi-C for cervical disc replacement to aid local decision-making

Medtech innovation briefing Published June 2016

Bair Hugger for measuring core temperature during perioperative care (MIB99)

Advice on the use of the Bair Hugger system for measuring core temperature during perioperative care to aid local decision-making

Medtech innovation briefing Published March 2017

SimpliCT laser-guided needle placement in interventional radiology (MIB98)

Advice on the use of SimpliCT laser-guided needle placement in interventional radiology (using CT or cone-beam CT imaging) to aid local decision-making

Medtech innovation briefing Published March 2017

TopClosure Tension Relief System for wound closure (MIB97)

Advice on the use of the TopClosure Tension Relief System for wound closure to aid local decision-making

Medtech innovation briefing Published March 2017

Smart One for measuring lung function (MIB96)

Advice on the use of Smart One for measuring lung function to aid local decision-making

Medtech innovation briefing Published February 2017

Shared decision making (KTT23)

This document summarises the evidence base on shared decision making. It is a key therapeutic topic that has been identified to support Medicines Optimisation. It is not formal NICE guidance.

Key therapeutic topic Published March 2019 Last updated September 2019

Chemotherapy dose standardisation (KTT22)

This document summarises the evidence base on chemotherapy dose standardisation. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published February 2018 Last updated September 2019

Medicines optimisation in chronic pain (KTT21)

This document summarises the evidence base on medicines optimisation in chronic pain. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2017 Last updated September 2019

Safer insulin prescribing (KTT20)

This document summarises the evidence base on safer insulin prescribing. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2017 Last updated September 2019

Renin-angiotensin system drugs: dual therapy (KTT2)

The key therapeutic topic renin-angiotensin system drugs: dual therapy has been retired from the 2017 update of medicines optimisation: key therapeutic topics. The version published in 2016 is available here for information but it has not been updated since February 2016. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated February 2016

Psychotropic medicines in people with learning disabilities whose behaviour challenges (KTT19)

This document summarises the evidence base on psychotropic medicines in people with learning disabilities whose behaviour challenges. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2017 Last updated September 2019

Multimorbidity and polypharmacy (KTT18)

This document summarises the evidence base on multimorbidity and polypharmacy. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2017 Last updated September 2019

Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI (KTT17)

This document summarises the evidence base on the use of medicines in people with or at increased risk of acute kidney injury. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published February 2016 Last updated September 2019

Anticoagulants, including direct-acting oral anticoagulants (DOACs) (KTT16)

This key therapeutic topic has been reincluded in the September 2019 update of medicines optimisation: key therapeutic topics. This document summarises the evidence base on anticoagulants, including direct-acting oral anticoagulants (DOACs). It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published February 2016 Last updated September 2019

Biosimilar medicines (KTT15)

The key therapeutic topic biosimilar medicines has been retired from the 2019 update of medicines optimisation: key therapeutic topics. The version published in 2018 is available here for information but it has not been updated since February 2018. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published February 2016 Last updated February 2018

Wound care products (KTT14)

This document summarises the evidence base on wound care products. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated September 2019

Non-steroidal anti-inflammatory drugs (KTT13)

The key therapeutic topic non-steroidal anti-inflammatory drugs has been retired from the 2019 update of medicines optimisation: key therapeutic topics. The version published in 2018 is available here for information but it has not been updated since February 2018. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated February 2018

Laxatives (KTT1)

The key therapeutic topic laxatives has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015

Zio Service for detecting cardiac arrhythmias (MIB101)

Advice on the use of the Zio Service (a remote cardiac monitoring system) for detecting cardiac arrhythmias to aid local decision-making

Medtech innovation briefing Published March 2017

Mollii suit for spasticity (MIB100)

Advice on the use of Mollii suit (formerly Elektrodress; a therapeutic electrical stimulation jacket and trousers) for spasticity to aid local decision-making

Medtech innovation briefing Published March 2017

The Versajet II hydrosurgery system for surgical debridement of acute and chronic wounds and burns (MIB1)

Advice on the use of the Versajet II hydrosurgery system for surgical debridement of acute and chronic wounds and burns to aid local decision-making

Medtech innovation briefing Published February 2014

End-tidal Control software for use with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia (MIB10)

Advice on the use of End-tidal Control software with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia..

Medtech innovation briefing Published September 2014

Antimicrobial stewardship: prescribing antibiotics (KTT9)

This document summarises the evidence base on antimicrobial stewardship: prescribing antibiotics. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated September 2019

First-choice antidepressant use in adults with depression or generalised anxiety disorder (KTT8)

The key therapeutic topic first-choice antidepressant use in adults with depression or generalised anxiety disorder has been retired from the 2017 update of medicines optimisation: key therapeutic topics. The version published in 2016 is available here for information but it has not been updated since February 2016. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated February 2016

Antipsychotics in people living with dementia (KTT7)

This document summarises the evidence base on antipsychotics in people living with dementia. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated September 2019

Hypnotics (KTT6)

This document summarises the evidence base on hypnotics. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated September 2019

Asthma: medicines safety priorities (KTT5)

This document summarises the evidence base on asthma: medicines safety priorities. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated September 2019

Lipid-modifying drugs (KTT3)

This key therapeutic topic has been reincluded in the September 2019 update of medicines optimisation: key therapeutic topics. This document summarises the evidence base on lipid-modifying drugs. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated September 2019

Suicide prevention: optimising medicines and reducing access to medicines as a means of suicide (KTT24)

This document summarises the evidence base on suicide prevention: optimising medicines and reducing access to medicines as a means of suicide. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published March 2019 Last updated September 2019

Type 2 diabetes mellitus: medicines optimisation priorities (KTT12)

This document summarises the evidence base on type 2 diabetes mellitus: medicines optimisation priorities. It is a key therapeutic topic that has been identified to support medicines optimisation. It is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated September 2019

Minocycline (KTT11)

The key therapeutic topic minocycline has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015

Leukomed Sorbact for preventing surgical site infection (MIB197)

Advice on the use of Leukomed Sorbact for preventing surgical site infection (SSI) to aid local decision making

Medtech innovation briefing Published November 2019

Antimicrobial prescribing: meropenem with vaborbactam (ES21)

Summary of the evidence on antimicrobial prescribing of meropenem with vaborbactam (Vaborem) to inform local NHS planning and decision making

Evidence summary: antimicrobial prescribing Published November 2019

Antimicrobial prescribing: ceftolozane with tazobactam for treating hospital-acquired pneumonia, including ventilator-associated pneumonia (ES22)

Summary of the evidence on the antimicrobial prescribing of ceftolozane with tazobactam for hospital-acquired pneumonia, including ventilator-associated

Evidence summary: antimicrobial prescribing Published December 2019

Alpha-Stim AID for anxiety (MIB193)

Advice on the use of Alpha-Stim AID for anxiety to aid local decision making

Medtech innovation briefing Published September 2019

Non-cystic fibrosis bronchiectasis: long-term azithromycin (ESUOM38)

Summary of the evidence on long-term azithromycin for treating non-cystic fibrosis bronchiectasis to inform local NHS planning and decision-making

Evidence summary Published November 2014

Cystic fibrosis: long-term azithromycin (ESUOM37)

Summary of the evidence on long-term azithromycinoral for treating cystic fibrosis (CF) to inform local NHS planning and decision-making

Evidence summary Published November 2014

Systemic lupus erythematosus: oral mycophenolate (ESUOM36)

Summary of the evidence on oral mycophenolate for systemic lupus erythematosus (SLE) to inform local NHS planning and decision-making

Evidence summary Published November 2014

Immune (idiopathic) thrombocytopenic purpura: rituximab (ESUOM35)

Summary of the evidence on rituximab for immune (idiopathic) thrombocytopenic purpura in adults to inform local NHS planning and decision-making

Evidence summary Published October 2014

Management of vomiting in children and young people with gastroenteritis: ondansetron (ESUOM34)

Summary of the evidence on ondansetron for the management of vomiting in children and young people with acute gastroenteritis...

Evidence summary Published October 2014

Migraine prophylaxis: flunarizine (ESUOM33)

Summary of the evidence on flunarizine for treating migraine prophylaxis to inform local NHS planning and decision-making

Evidence summary Published September 2014

Scleroderma: oral mycophenolate (ESUOM32)

Summary of the evidence on oral mycophenolate for systemic sclerosis (scleroderma) to inform local NHS planning and decision-making

Evidence summary Published July 2014

Chronic urticaria: off-label doses of cetirizine (ESUOM31)

Summary of the evidence on off-label doses of cetirizine for chronic urticaria (hives) to inform local NHS planning and decision-making

Evidence summary Published July 2014

Pouchitis: rifaximin (ESUOM30)

Summary of the evidence on rifaximin for treating pouchitis to inform local NHS planning and decision-making

Evidence summary Published March 2014