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Sir Andrew Dillon to stand down as NICE chief executive

Chief executive has been at the helm of the institute since it was founded in April 1999

News Published August 2019 Last updated August 2019

NICE to work with company on addressing issues in appraisals of cannabidiol for treating difficult to control epilepsies

NICE has today (23 August 2019) announced its intention to work with GW Pharma to address the issues highlighted by its independent appraisal committee in its evaluation of cannabidiol for treating 2 types of severe treatment-resistant epilepsy.

News Published August 2019 Last updated August 2019

NICE recommends novel gene therapy treatment for rare inherited eye disorder

It's estimated that 86 people would be eligible for treatment with voretigene neparvovec in England

News Published September 2019 Last updated September 2019

Tailored support should be offered to those affected by suspected suicide, says NICE

Providing support after a suspected suicide can reduce this risk, especially when tailored to the person’s needs.

News Published September 2019 Last updated September 2019

Applications now open for NICE's prestigious fellows and scholars programmes

Recruitment for the 2020 intake is open until 28 October 2019

News Published September 2019 Last updated September 2019

Children with rare inherited condition to benefit from drug through managed access agreement

It is estimated that in the UK there are around 30 to 50 children living with the condition

News Published September 2019 Last updated September 2019

Three areas where NICE's collaboration with CMAC can make a difference

Heidi Livingstone, senior public involvement adviser within NICE's Public Involvement Programme, reflects on the partnership with CMAC

News Published September 2019 Last updated September 2019

New lung cancer treatment option approved by NICE

Another new life-extending treatment for some people with lung cancer is to be made available on the Cancer Drugs Fund (CDF) following its approval by NICE in draft guidance published today (8 August 2019).

News Published August 2019 Last updated August 2019

NICE draft guidance and NHS England review highlight need for more research on cannabis-based medicinal products

NICE has today (8 August 2019) published its draft recommendations on the use of cannabis-based medicinal products following a comprehensive evaluation of their clinical and cost-effectiveness.

News Published August 2019 Last updated August 2019

NICE recommends additional treatment option for people with early breast cancer

NICE has today (7 August 2019) published draft guidance recommending neratinib as an additional treatment for some people with early hormone-receptor-positive, human epidermal growth factor receptor 2 (HER2)-positive breast cancer.

News Published August 2019 Last updated August 2019

Offer daily aspirin to those with inherited genetic condition to reduce the risk of colorectal cancer

Aspirin taken daily for 2 years or more could reduce the risk of colorectal cancer in people with Lynch syndrome (LS), says NICE in new draft updated guidance.

News Published August 2019 Last updated August 2019

Unpaid carers need more support to cope with financial and emotional stress

NICE has published new draft guidance which aims to improve the wellbeing of adults who provide unpaid care for people over 16 years old.

News Published August 2019 Last updated August 2019

Lanadelumab for preventing recurrent attacks of hereditary angioedema [ID1268]

In development [GID-TA10333] Expected publication date: 09 October 2019

Technology appraisal guidance In development

Clostridium botulinum neurotoxin type A for treating chronic sialorrhoea [ID1150]

In development [GID-TA10296] Expected publication date: 09 October 2019

Technology appraisal guidance In development

Voretigene neparvovec for treating inherited retinal dystrophies caused by RPE65 gene mutations ID1054

In development [GID-HST10025] Expected publication date: 09 October 2019

Highly specialised technologies guidance In development

Improving service user experience in adult mental health services

Kathryn Mason, Head of Hospital Inspection (mental health), discusses the work CQC is undertaking to improve the quality and safety of mental health services

News Published July 2019 Last updated July 2019

Innovative treatment for gynaecological cancers approved for Cancer Drugs Fund

Olaparib, a medicine that has previously been used at a later stage in the treatment of advanced ovarian cancer, has now been approved by NICE as a first-line maintenance treatment.

News Published July 2019 Last updated July 2019

People's experience in adult social care services: improving the experience of care and support for people using adult social care services (NG86)

This guideline covers the care and support of adults receiving social care in their own homes, residential care and community settings. It aims to help people understand what care they can expect and to improve their experience by supporting them to make decisions about their care.

NICE guideline Published February 2018

Prostate cancer: diagnosis and management (NG131)

This guideline covers the diagnosis and management of prostate cancer in secondary care, including information on the best way to diagnose and identify different stages of the disease, and how to manage adverse effects of treatment. It also includes recommendations on follow-up in primary care for people diagnosed with prostate cancer.

NICE guideline Published May 2019

Hip fracture: management (CG124)

This guideline covers managing hip fracture in adults. It aims to improve care from the time people aged 18 and over are admitted to hospital through to when they return to the community. Recommendations emphasise the importance of early surgery and coordinating care through a multidisciplinary hip fracture programme to help people recover faster and regain their mobility.

Clinical guideline Published June 2011 Last updated May 2017

Autism spectrum disorder in under 19s: recognition, referral and diagnosis (CG128)

This guideline covers recognising and diagnosing autism spectrum disorder in children and young people from birth up to 19 years. It also covers referral. It aims to improve the experience of children, young people and those who care for them.

Clinical guideline Published September 2011 Last updated December 2017

Service user experience in adult mental health: improving the experience of care for people using adult NHS mental health services (CG136)

This guideline covers the components of a good experience of service use. It aims to make sure that all adults using NHS mental health services have the best possible experience of care.

Clinical guideline Published December 2011

Pregnancy and complex social factors: a model for service provision for pregnant women with complex social factors (CG110)

This guideline covers antenatal care for all pregnant women with complex social factors (particularly alcohol or drug misuse, recent migrant or asylum seeker status, difficulty reading or speaking English, aged under 20, domestic abuse). It offers advice on improving access to care, maintaining contact with antenatal carers, and additional information and support for these women.

Clinical guideline Published September 2010

Delirium: prevention, diagnosis and management (CG103)

This guideline covers diagnosing and treating delirium in people aged 18 and over in hospital and in long-term residential care or a nursing home. It also covers identifying people at risk of developing delirium in these settings and preventing onset. It aims to improve diagnosis of delirium and reduce hospital stays and complications.

Clinical guideline Published July 2010 Last updated March 2019

Metastatic malignant disease of unknown primary origin in adults: diagnosis and management (CG104)

This guideline covers diagnosing and managing secondary cancers in people aged 18 and over when the site of the primary cancer is unknown. This includes people who have had treatment for cancer before. It aims to improve quality of life by offering advice on tests for identifying the site of the primary cancer and options for managing the person’s condition when this cannot be found.

Clinical guideline Published July 2010

Chronic kidney disease (stage 4 or 5): management of hyperphosphataemia (CG157)

This guideline covers managing hyperphosphataemia in children, young people and adults with stage 4 or 5 chronic kidney disease. It makes recommendations on dietary management and phosphate binders, to reduce variation in care and the risk of hyperparathyroidism for people with chronic kidney disease.

Clinical guideline Published March 2013

Self-harm in over 8s: short-term management and prevention of recurrence (CG16)

This guideline covers the short-term management and prevention of self-harm in people aged 8 and over, regardless of whether accompanied by mental illness. It covers the first 48 hours following an act of self-harm, but does not address the longer-term psychiatric care of people who self-harm.

Clinical guideline Published July 2004

Falls in older people: assessing risk and prevention (CG161)

This guideline covers assessment of fall risk and interventions to prevent falls in people aged 65 and over. It aims to reduce the risk and incidence of falls and the associated distress, pain, injury, loss of confidence, loss of independence and mortality.

Clinical guideline Published June 2013

Hyperglycaemia in acute coronary syndromes: management (CG130)

This guideline covers managing hyperglycaemia in the first 48 hours for adults admitted to hospital for acute coronary syndromes. It aims to improve initial management of hyperglycaemia and ensure that adults are given advice on their diabetes risk and how to reduce it.

Clinical guideline Published October 2011

Stable angina: management (CG126)

This guideline covers managing stable angina in people aged 18 and over. It outlines the importance of addressing the person’s concerns about stable angina and the roles of medical therapy and revascularisation.

Clinical guideline Published July 2011 Last updated August 2016

Common mental health problems: identification and pathways to care (CG123)

This guideline covers care for people aged 18 and over with common mental health problems, with a focus on primary care. It aims to improve access to services for adults and how mental health problems are identified and assessed, and makes recommendations on local care pathways.

Clinical guideline Published May 2011

Colorectal cancer prevention: colonoscopic surveillance in adults with ulcerative colitis, Crohn's disease or adenomas (CG118)

This guideline covers using colonoscopy to check for signs of bowel cancer in people aged 18 and over with ulcerative colitis or Crohn’s disease (types of inflammatory bowel disease) or adenomas (also known as polyps). It aims to prevent cancer and prolong life by offering advice on identifying early bowel cancer in adults most at risk.

Clinical guideline Published March 2011

Food allergy in under 19s: assessment and diagnosis (CG116)

This guideline covers assessing and managing food allergy in children and young people under 19. It aims to improve symptoms such as faltering growth and eczema by offering advice on how to identify food allergy and when to refer to secondary or specialist care.

Clinical guideline Published February 2011

Sedation in under 19s: using sedation for diagnostic and therapeutic procedures (CG112)

This guideline covers the assessment, preparation, training and monitoring needed when using sedation in people aged under 19. It aims to help healthcare professionals decide when sedation is the most clinically and cost effective option for reducing pain and anxiety during operations for children and young people.

Clinical guideline Published December 2010

Bedwetting in under 19s (CG111)

This guideline covers assessing and treating bedwetting in people aged under 19. It aims to reduce bedwetting and the distress this causes by explaining what to ask in an assessment, what advice to provide, and which treatments are effective.

Clinical guideline Published October 2010

Coexisting severe mental illness (psychosis) and substance misuse: assessment and management in healthcare settings (CG120)

This guideline covers assessing and managing people aged 14 years and over with coexisting severe mental illness (psychosis) and substance misuse. It aims to help healthcare professionals guide people with psychosis with coexisting substance misuse to stabilise, reduce or stop their substance misuse, to improve treatment adherence and outcomes, and to enhance their lives.

Clinical guideline Published March 2011

Ovarian cancer: recognition and initial management (CG122)

This guideline covers detecting, diagnosing and treating women (18 years and older) who have, or are suspected of having, epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer or borderline ovarian cancer. It aims to enable earlier detection of ovarian cancer and improve initial treatment.

Clinical guideline Published April 2011

Headaches in over 12s: diagnosis and management (CG150)

This guideline covers advice on the diagnosis and management of tension-type headache, migraine (including migraine with aura and menstrual-related migraine), cluster headache and medication overuse headache in young people (aged 12 years and older) and adults. It aims to improve the recognition and management of headaches, with more targeted treatment to improve the quality of life for people with headaches, and to reduce unnecessary investigations.

Clinical guideline Published September 2012 Last updated November 2015

Sickle cell disease: managing acute painful episodes in hospital (CG143)

This guideline covers managing acute painful sickle cell episodes in children, young people and adults who present at hospital, from presentation until when they are discharged. It aims to reduce variation in how acute episodes are managed in hospital, focusing on effective, prompt and safe pain relief.

Clinical guideline Published June 2012

Neonatal infection (early onset): antibiotics for prevention and treatment (CG149)

This guideline covers preventing infection within 72 hours of birth in healthy babies, treating pregnant women whose baby is at risk, and caring for babies who have a suspected or confirmed infection. It aims to reduce delays in recognising and treating sick babies and prevent unnecessary use of antibiotics.

Clinical guideline Published August 2012

Venous thromboembolic diseases: diagnosis, management and thrombophilia testing (CG144)

This guideline covers the diagnosis and management of venous thromboembolic diseases in adults (aged 18 and over), and the role of thrombophilia testing. It aims to clarify which diagnostic tests should be used, reduce variation in pharmacological therapies, and provide guidance on when thrombophilia testing is useful.

Clinical guideline Published June 2012 Last updated November 2015

Autism spectrum disorder in adults: diagnosis and management (CG142)

This guideline covers diagnosing and managing suspected or confirmed autism spectrum disorder (autism, Asperger’s syndrome and atypical autism) in people aged 18 and over. It aims to improve access and engagement with interventions and services, and the experience of care, for people with autism.

Clinical guideline Published June 2012 Last updated August 2016

Healthcare-associated infections: prevention and control in primary and community care (CG139)

This guideline covers preventing and controlling healthcare-associated infections in children, young people and adults in primary and community care settings. It provides a blueprint for the infection prevention and control precautions that should be applied by everyone involved in delivering NHS care and treatment.

Clinical guideline Published March 2012 Last updated February 2017

Patient experience in adult NHS services: improving the experience of care for people using adult NHS services (CG138)

This guideline covers the components of a good patient experience. It aims to make sure that all adults using NHS services have the best possible experience of care.

Clinical guideline Published February 2012

Organ donation for transplantation: improving donor identification and consent rates for deceased organ donation (CG135)

This guideline covers identifying people who wish to donate their organs after their death. It offers advice on how to approach families and carers of people who are nearing the end of life and how to seek consent for organ donation. It aims to promote discussion of organ donation as part of end-of-life care and to increase the number of organs available for people waiting for a transplant.

Clinical guideline Published December 2011 Last updated December 2016

Self-harm in over 8s: long-term management (CG133)

This guideline covers the longer-term psychological treatment and management of self-harm in people aged 8 and over. It aims to improve the quality of care and support for people who self harm and covers both single and recurrent episodes of self-harm.

Clinical guideline Published November 2011

Colorectal cancer: diagnosis and management (CG131)

This guideline covers diagnosing and managing colorectal (bowel) cancer in people aged 18 and over. It aims to improve quality of life and survival for adults with colorectal cancer through early diagnosis and staging, management of local disease according to risk of recurrence (high, moderate, low) and management of secondary tumours (metastatic disease).

Clinical guideline Published November 2011 Last updated December 2014

Meningitis (bacterial) and meningococcal septicaemia in under 16s: recognition, diagnosis and management (CG102)

This guideline covers recognising, diagnosing and managing bacterial meningitis and meningococcal septicaemia (blood poisoning) in babies, children and young people under 16. It aims to reduce deaths and disability by promoting early recognition of symptoms and timely effective management.

Clinical guideline Published June 2010 Last updated February 2015

Barrett's oesophagus: ablative therapy (CG106)

This guideline covers endoscopy treatments for people aged 18 and over with Barrett’s oesophagus and high-grade dysplasia or intramucosal cancer. It offers advice on which types of endoscopy treatments should be offered and how these should be used. It aims to improve choice of treatment for adults with Barrett’s oesophagus and improve quality of life and survival for those who cannot have surgery.

Clinical guideline Published August 2010

Transient loss of consciousness ('blackouts') in over 16s (CG109)

This guideline covers assessment, diagnosis and referral for people over 16 who have had a transient loss of consciousness (TLoC; also called a blackout). It aims to improve care for people with TLoC by specifying the most effective assessments and recommending when to refer to a specialist.

Clinical guideline Published August 2010 Last updated September 2014