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Procalcitonin testing for diagnosing and monitoring sepsis (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay) (DG18)

Evidence-based recommendations on procalcitonin testing for diagnosing and monitoring sepsis (AVIDA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive..

Diagnostics guidance Published October 2015

Myocardial infarction (acute): Early rule out using high-sensitivity troponin tests (Elecsys Troponin T high-sensitive, ARCHITECT STAT High Sensitive Troponin-I and AccuTnI+3 assays) (DG15)

Evidence-based recommendations on high-sensitivity troponin tests for the early rule-out of acute myocardial infarction (AMI)

Diagnostics guidance Published October 2014

Atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers (the CoaguChek XS system) (DG14)

Evidence-based recommendations on point-of-care coagulometers (the CoaguChek XS system) to self-monitor blood clotting

Diagnostics guidance Published September 2014 Last updated December 2017

Measuring fractional exhaled nitric oxide concentration in asthma: NIOX MINO, NIOX VERO and NObreath (DG12)

Evidence-based recommendations on the NIOX MINO, NIOX VERO and Nobreath devices to measure fractional exhaled nitric oxide concentration in asthma

Diagnostics guidance Published April 2014

Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel (DG11)

Evidence-based recommendations on faecal calprotectin diagnostic tests for inflammatory diseases of the bowel

Diagnostics guidance Published October 2013

The EOS 2D/3D imaging system (DG1)

Evidence-based recommendations on the EOS 2D/3D imaging system for radiological examinations

Diagnostics guidance Published October 2011

SeHCAT (tauroselcholic [75 selenium] acid) for the investigation of diarrhoea due to bile acid malabsorption in people with diarrhoea-predominant irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection (DG7)

Evidence-based recommendations on SeHCAT (tauroselcholic [75 selenium] acid) for investigating diarrhoea due to bile acid malabsorption (BAM)

Diagnostics guidance Published November 2012

Depth of anaesthesia monitors – Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M (DG6)

Evidence-based recommendations on the Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M depth of anaesthesia monitors

Diagnostics guidance Published November 2012

SonoVue (sulphur hexafluoride microbubbles) – contrast agent for contrast-enhanced ultrasound imaging of the liver (DG5)

Evidence-based recommendations on theSonoVue (sulphur hexafluoride microbubbles) contrast agent for contrast-enhanced ultrasound imaging of the liver

Diagnostics guidance Published August 2012

Therapeutic monitoring of TNF-alpha inhibitors in rheumatoid arthritis (DG36)

Evidence-based recommendations on enzyme-linked immunosorbent assay (ELISA) tests for therapeutic monitoring of TNF-alpha inhibitors in rheumatoid arthritis

Diagnostics guidance Published July 2019

Rapid tests for group A streptococcal infections in people with a sore throat (DG38)

Evidence-based recommendations on rapid tests for group A streptococcal (strep A) infections in people aged 5 and over with a sore throat

Diagnostics guidance Published November 2019

Detecting, managing and monitoring haemostasis: viscoelastometric point‑of‑care testing (ROTEM, TEG and Sonoclot systems) (DG13)

Evidence-based recommendations on viscoelastometric point-of-care testing (ROTEM, TEG and Sonoclot systems) to detect, manage and monitor haemostasis

Diagnostics guidance Published August 2014

Intraoperative tests (RD‑100i OSNA system and Metasin test) for detecting sentinel lymph node metastases in breast cancer (DG8)

Evidence-based recommendations on the RD-100i OSNA system and Metasin test for detecting sentinel lymph node metastases in breast cancer

Diagnostics guidance Published August 2013

EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (DG9)

Evidence-based recommendations on EGFR-TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (NSCLC)

Diagnostics guidance Published August 2013

Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment (DG16)

Evidence-based recommendations on the My5-FU assay for guiding dose adjustment for fluorouracil chemotherapy

Diagnostics guidance Published December 2014

Point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast (DG37)

Evidence-based recommendations on point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast

Diagnostics guidance Published November 2019

Leg ulcer infection: antimicrobial prescribing

In development [GID-NG10133] Expected publication date: 11 February 2020

Antimicrobial prescribing guideline In development

Impetigo: antimicrobial prescribing

In development [GID-NG10134] Expected publication date: 11 February 2020

Antimicrobial prescribing guideline In development

Clostridium difficile infection: antimicrobial prescribing

In development [GID-NG10144] Expected publication date: 30 September 2020

Antimicrobial prescribing guideline In development

Diabetic foot infection: antimicrobial prescribing

In development [GID-NG10132] Expected publication date: 11 October 2019

Antimicrobial prescribing guideline In development

Secondary infection of common skin conditions including eczema: antimicrobial prescribing

In development [GID-NG10135] Expected publication date: 10 November 2020

Antimicrobial prescribing guideline In development

Human and animal bites: antimicrobial prescribing

In development [GID-NG10137] Expected publication date: 30 June 2020

Antimicrobial prescribing guideline In development

Skin abscess: antimicrobial prescribing

In development [GID-NG10163] Expected publication date: TBC

Antimicrobial prescribing guideline In development

Insect bites and stings: antimicrobial prescribing

In development [GID-NG10136] Expected publication date: 30 June 2020

Antimicrobial prescribing guideline In development

Testing strategies for Lynch syndrome in people with endometrial cancer

In development [GID-DG10033] Expected publication date: 29 July 2020

Diagnostics guidance In development

QAngio XA 3D/ QFR and CAAS vFFR imaging software for assessing the functional significance of coronary obstructions during invasive coronary angiography

In development [GID-DG10034] Expected publication date: 30 September 2020

Diagnostics guidance In development

High-sensitivity troponin for the early rule out of acute myocardial infarction

In development [GID-DG10035] Expected publication date: 26 August 2020

Diagnostics guidance In development

Implantable cardiac monitors to detect atrial fibrillation after cryptogenic stroke

In development [GID-DG10023] Expected publication date: 27 May 2020

Diagnostics guidance In development

Implantable cardiac monitors to detect atrial fibrillation after cryptogenic stroke: diagnostics consultation

We are listening to your views on this diagnostics guidance. Comments close 04 February 2020.

Diagnostics guidance In consultation

PredictSURE-IBD and IBDX to guide personalised treatment of Crohn's disease

In development [GID-DG10029] Expected publication date: 26 August 2020

Diagnostics guidance In development

Therapeutic hypothermia with intracorporeal temperature monitoring for hypoxic perinatal brain injury (IPG347)

Evidence-based recommendations on therapeutic hypothermia with intracorporeal temperature monitoring for treating hypoxic perinatal brain injury

Interventional procedures guidance Published May 2010

Mini-incision surgery for total knee replacement (IPG345)

Evidence-based recommendations on mini-incision surgery for total knee replacement

Interventional procedures guidance Published May 2010

Epithelial radiofrequency ablation for Barrett's oesophagus (IPG344)

Evidence-based recommendations on epithelial radiofrequency ablation for treating Barrett's oesophagus

Interventional procedures guidance Published May 2010

Haemorrhoidal artery ligation (IPG342)

Evidence-based recommendations on haemorrhoidal artery ligation for treating haemorrhoids (piles)

Interventional procedures guidance Published May 2010

Prosthetic intervertebral disc replacement in the cervical spine (IPG341)

Evidence-based recommendations on prosthetic intervertebral disc replacement in the cervical spine for treating degenerative cervical disc disease

Interventional procedures guidance Published May 2010

Macular translocation with 360° retinotomy for wet age-related macular degeneration (IPG340)

Evidence-based recommendations on macular translocation with 360° retinotomy for treating wet (exudative) age-related macular degeneration (AMD)

Interventional procedures guidance Published May 2010

Circular stapled haemorrhoidectomy (IPG34)

Evidence-based recommendations on circular stapled haemorrhoidectomy for treating internal haemorrhoids

Interventional procedures guidance Published December 2003

Limited macular translocation for wet age-related macular degeneration (IPG339)

Evidence-based recommendations on limited macular translocation for treating wet (exudative) age-related macular degeneration (AMD)

Interventional procedures guidance Published May 2010

Laparoscopic radical hysterectomy for early stage cervical cancer (IPG338)

Evidence-based recommendations on laparoscopic radical hysterectomy for treating early stage cervical cancer

Interventional procedures guidance Published May 2010

Endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesions (IPG337)

Evidence-based recommendations on endobronchial ultrasound-guided transbronchial biopsy for treating peripheral lung lesions (pulmonary nodules)

Interventional procedures guidance Published March 2010

Transcatheter endovascular closure of perimembranous ventricular septal defect (IPG336)

Evidence-based recommendations on transcatheter endovascular closure of perimembranous ventricular septal defect (VSD) for treating holes in the heart

Interventional procedures guidance Published March 2010

Endoscopic submucosal dissection of lower gastrointestinal lesions (IPG335)

Evidence-based recommendations on endoscopic submucosal dissection of lower gastrointestinal lesions

Interventional procedures guidance Published March 2010

Arteriovenous crossing sheathotomy for branch retinal vein occlusion (IPG334)

Evidence-based recommendations on arteriovenous crossing sheathotomy for treating branch retinal vein occlusion (BRVO, retinal vascular thrombosis)

Interventional procedures guidance Published March 2010

Therapeutic endoscopic division of epidural adhesions (IPG333)

Evidence-based recommendations on therapeutic endoscopic division of epidural adhesions for back or leg pain from adhesions around the spinal nerve roots

Interventional procedures guidance Published February 2010

Surgical correction of hallux valgus using minimal access techniques (IPG332)

Evidence-based recommendations on surgical correction using minimal access techniques for treating hallux valgus (bunions)

Interventional procedures guidance Published February 2010

Cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis (IPG331)

Evidence-based recommendations on cytoreduction surgery and hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis (cancer)

Interventional procedures guidance Published February 2010

Vagus nerve stimulation for treatment-resistant depression (IPG330)

Evidence-based recommendations on vagus nerve stimulation for treatment-resistant depression

Interventional procedures guidance Published December 2009

Endoaortic balloon occlusion for cardiac surgery (IPG261)

Evidence-based recommendations on endoaortic balloon occlusion for heart surgery

Interventional procedures guidance Published May 2008