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  1. The MAGEC system for spinal lengthening in children with scoliosis (MTG18)

     April 2020: This guidance has been withdrawn while the MHRA conducts an investigation into the MAGEC system. The MHRA issued a Medical Device Alert MDA/2020/011 for all MAGEC systems. This is in response to the manufacturer’s latest Field Safety Notice and previous field safety notices for problems that may require early removal of devices and lead to inadequate treatment. The MHRA is not recommending prophylactic removal of devices but the supply of all MAGEC systems is suspended in the UK while the MHRA investigation is ongoing. The MHRA has set out the following actions: Do not implant MAGEC rods in the UK until further notice. Identify all patients implanted with a MAGEC System and ensure systems are in place to follow up these patients.

  2. Endoscopic thoracic sympathectomy for primary hyperhidrosis of the upper limb (IPG487)

    Evidence-based recommendations on endoscopic thoracic sympathectomy for primary hyperhidrosis (excess sweating) of the upper limb (palm of hand and armpit)

  3. Arthroscopic radiofrequency chondroplasty for discrete chondral defects of the knee (IPG493)

    Evidence-based recommendations on arthroscopic radiofrequency chondroplasty for discrete chondral defects of the articular cartilage in the knee

  4. Measuring fractional exhaled nitric oxide concentration in asthma: NIOX MINO, NIOX VERO and NObreath (DG12)

    Evidence-based recommendations on NIOX MINO, NIOX VERO and NObreath for measuring the amount of exhaled nitric oxide (FeNO) in the breath to help diagnose

  5. Transoral carbon dioxide laser surgery for primary treatment of oropharyngeal malignancy (IPG484)

    Evidence-based recommendations on transoral carbon dioxide (CO2) laser surgery for primary treatment of oropharyngeal malignancy (throat cancer)

  6. Faecal microbiota transplant for recurrent Clostridium difficile infection (IPG485)

    Evidence-based recommendations on faecal microbiota (bacteria) transplant for recurrent Clostridium difficile (C. difficile/C. diff) infection

  7. Electrochemotherapy for primary basal cell carcinoma and primary squamous cell carcinoma (IPG478)

    Evidence-based recommendations on electrochemotherapy for primary basal cell carcinoma (BCC) and primary squamous cell carcinoma (SCC) (skin cancer)

  8. Endoscopic thoracic sympathectomy for primary facial blushing (IPG480)

    Evidence-based recommendations on endoscopic thoracic sympathectomy (cutting off nerve signals to stop blushing) for primary facial blushing

  9. Optical coherence tomography to guide percutaneous coronary intervention (IPG481)

    Evidence-based recommendations on optical coherence tomography to guide percutaneous coronary intervention (near-infrared light for artery imaging)

  10. Insertion of prostatic urethral lift implants to treat lower urinary tract symptoms secondary to benign prostatic hyperplasia (IPG475)

    Evidence-based recommendations on prostatic urethral lift implants to treat lower tract symptoms secondary to benign prostate hyperplasia (enlarged prostate)

  11. Percutaneous closure of patent foramen ovale to prevent recurrent cerebral embolic events (IPG472)

    Evidence-based recommendations on percutaneous closure of patent foramen ovale (PFO/hole in the heart) to prevent recurrent cerebral embolic events

  12. Ultra-radical (extensive) surgery for advanced ovarian cancer (IPG470)

    Evidence-based recommendations on ultra-radical (extensive) surgery for advanced ovarian cancer (removing cancerous tissue from all organs)

  13. Implantation of a duodenal–jejunal bypass sleeve for managing obesity (IPG471)

    Evidence-based recommendations on the implantation of a duodenal–jejunal bypass sleeve (temporary implant in the gut) for managing obesity

  14. Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel (DG11)

    Evidence-based recommendations on faecal calprotectin tests for distinguishing between inflammatory bowel diseases (such as Crohn’s disease and ulcerative

  15. Photochemical corneal collagen cross‑linkage using riboflavin and ultraviolet A for keratoconus and keratectasia (IPG466)

    Evidence-based recommendations on photochemical corneal collagen cross-linkage using riboflavin and ultraviolet A for keratoconus and keratectasia

  16. Endoscopic radiofrequency ablation for gastro-oesophageal reflux disease (IPG461)

    Evidence-based recommendations on endoscopic radiofrequency ablation for gastro-oesophageal reflux disease (acid reflux/ GORD/GERD)

  17. Insertion and use of implantable pulmonary artery pressure monitors in chronic heart failure (IPG463)

    Evidence-based recommendations on the insertion and use of implantation pulmonary artery pressure monitors for chronic heart failure

  18. EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (DG9)

    Evidence-based recommendations on testing for epidermal growth factor receptor tyrosine kinase (EGFR–TK) mutations in untreated, locally advanced or metastatic

  19. Intraoperative tests (RD‑100i OSNA system and Metasin test) for detecting sentinel lymph node metastases in breast cancer (DG8)

    Evidence-based recommendations on the RD-100i OSNA system and Metasin test for detecting sentinel lymph node metastases in people having breast cancer surgery

  20. Insertion of customised exposed titanium implants, without soft tissue cover, for complex orofacial reconstruction (IPG457)

    Evidence-based recommendations on inserting customised exposed titanium implants, (without soft tissue cover) for complex orofacial (face) reconstruction