Apremilast for treating moderate to severe plaque psoriasis (TA368)
Evidence-based recommendations on implantation of a corneal graft–keratoprosthesis for severe corneal opacity in wet blinking eyes
Evidence-based recommendations on living-donor liver transplantation
Evidence-based recommendations on sacral nerve stimulation for idiopathic chronic non-obstructive urinary retention
Evidence-based recommendations on ledipasvir–sofosbuvir (Harvoni) for treating some types (genotypes) of chronic hepatitis C
Evidence-based recommendations on ombitasvir–paritaprevir–ritonavir (Viekirax) with or without dasabuvir (Exviera) for some types of chronic hepatitis C
Evidence-based recommendations on vortioxetine (Brintellix) for treating major depressive episodes in adults
Evidence-based recommendations on implanting a baroreceptor stimulation device for resistant hypertension
This guidance has been updated and replaced by NICE technology appraisal guidance 476.
The appraisal has been withdrawn because Janssen withdrew their marketing authorisation on 1 May 2018. The availability of direct-acting antiviral combination treatments for hepatitis C has reduced the use of simeprevir, so the company has decided to discontinue it.
Evidence-based recommendations on idelalisib (Zydelig) for treating chronic lymphocytic leukaemia (CLL) in adults
NICE is unable to make a recommendation about the use in the NHS of paclitaxel as albumin-bound nanoparticles with carboplatin for untreated..
Evidence-based recommendations on tolvaptan (Jinarc) for treating autosomal dominant polycystic kidney disease (ADPKD)
Evidence-based recommendations on low energy contact X-ray brachytherapy (the Papillon technique) for treating early stage rectal cancer
Evidence-based recommendations on edoxaban (Lixiana) for preventing stroke and systemic embolism in people with non-valvular atrial fibrillation (AF)
NICE is unable to make a recommendation about the use in the NHS of ruxolitinib for treating polycythaemia vera...
Evidence-based recommendations on transcranial direct current stimulation (tDCS) for depression
Evidence-based recommendations on preoperative high dose rate brachytherapy for treating rectal cancer
Evidence-based recommendations on vedolizumab (Entyvio) for moderately to severely active Crohn's disease if TNF-alpha therapy has not worked or...
Evidence-based recommendations on edoxaban (Lixiana) for treating and preventing deep vein thrombosis (DVT) and pulmonary embolism
NICE is unable to make recommendations about the use of bevacizumab for treating relapsed, platinum-resistant epithelial ovarian, fallopian tube or…
This guidance has been replaced by NICE guideline NG17.
This guidance has been replaced by NICE guideline NG17.
Evidence-based recommendations on the insertion of a double balloon catheter for inducing labour in pregnant women without previous caesarean section
Evidence-based recommendations on joint distraction for knee osteoarthritis without alignment correction
Evidence-based recommendations on dexamethasone intravitreal implant (Ozurdex) for treating diabetic macular oedema
Evidence-based recommendations on secukinumab (Cosentyx) for treating moderate to severe plaque psoriasis
Evidence-based recommendations on aflibercept (Eylea) for treating diabetic macular oedema
Evidence-based recommendations on everolimus (Certican) for preventing organ rejection in people having a liver transplant
NICE is unable to make recommendations about the use of cangrelor for reducing atherothrombotic events in people undergoing percutaneous coronary…
Evidence-based recommendations on naloxegol (Moventig) for treating opioid-induced constipation that has had inadequate response to laxatives
Evidence-based recommendations on nintedanib (Vargatef) for treating locally advanced, metastatic, or locally recurrent non-small-cell lung cancer
Evidence-based recommendations on electrotherapy for treating grade I to III haemorrhoids in adults. This involves using electric current to shrink the
Evidence-based recommendations on the implantation of a sphenopalatine ganglion stimulation device for treating chronic cluster headaches
Evidence-based recommendations on the insertion of an epiretinal prosthesis for treating retinitis pigmentosa (RP)
Evidence-based recommendations on radiofrequency ablation for treating gastric antral vascular ectasia (GAVE) syndrome
This guidance has been updated and replaced by NICE interventional procedures guidance 670.
Evidence-based recommendations on hysteroscopic morcellation of uterine leiomyomas (uterine myomas or fibroids)
Evidence-based recommendations on suture fixation of acute disruption of the distal tibiofibular syndesmosis (ligament injuries)
Evidence-based recommendations on ultrasound-enhanced, catheter-directed thrombolysis for deep vein thrombosis (DVT)
Evidence-based recommendations on ultrasound-enhanced, catheter-directed thrombolysis for pulmonary embolism (PE)
Evidence-based recommendations on omalizumab (Xolair) for treating previously treated severe chronic spontaneous urticaria (hives)
Evidence-based recommendations on vedolizumab (Entyvio) for treating moderately to severely active ulcerative colitis in adults
Evidence-based recommendations on apixaban (Eliquis) for treating and preventing deep vein thrombosis (DVT) or pulmonary embolism
This guidance has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Evidence-based recommendations on obinutuzumab (Gazyvaro) with chlorambucil for treating untreated chronic lymphocytic leukaemia
Evidence-based recommendations on implanting a duodenal–jejunal bypass liner for managing type 2 diabetes
Evidence-based recommendations on endobronchial nitinol coils to improve lung function in emphysema (chronic obstructive pulmonary disease [COPD])
Evidence-based recommendations on the implantation of a left ventricular assist device for destination therapy in people ineligible for heart transplant
Evidence-based recommendations on the insertion of a balloon device to disimpact an engaged fetal head before an emergency caesarean section