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Depth of anaesthesia monitors – Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M (DG6)

Evidence-based recommendations on the Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M depth of anaesthesia monitors

Diagnostics guidance Published November 2012

SonoVue (sulphur hexafluoride microbubbles) – contrast agent for contrast-enhanced ultrasound imaging of the liver (DG5)

Evidence-based recommendations on theSonoVue (sulphur hexafluoride microbubbles) contrast agent for contrast-enhanced ultrasound imaging of the liver

Diagnostics guidance Published August 2012

Atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers (the CoaguChek XS system) (DG14)

Evidence-based recommendations on point-of-care coagulometers (the CoaguChek XS system) to self-monitor blood clotting

Diagnostics guidance Published September 2014 Last updated December 2017

Lead-I ECG devices for detecting symptomatic atrial fibrillation using single time point testing in primary care (DG35)

Evidence-based recommendations on lead-I ECG devices for detecting symptomatic atrial fibrillation using single time point testing in primary care

Diagnostics guidance Published May 2019

Tests in secondary care to identify people at high risk of ovarian cancer (DG31)

Evidence-based recommendations on tests (IOTA ADNEX, Overa, RMI I, ROMA, IOTA Simple Rules) in secondary care to identify people at high risk of ovarian cancer

Diagnostics guidance Published November 2017

Point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast (DG37)

Evidence-based recommendations on point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast

Diagnostics guidance Published November 2019

Intraoperative tests (RD‑100i OSNA system and Metasin test) for detecting sentinel lymph node metastases in breast cancer (DG8)

Evidence-based recommendations on the RD-100i OSNA system and Metasin test for detecting sentinel lymph node metastases in breast cancer

Diagnostics guidance Published August 2013

EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (DG9)

Evidence-based recommendations on EGFR-TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancer (NSCLC)

Diagnostics guidance Published August 2013

Detecting, managing and monitoring haemostasis: viscoelastometric point‑of‑care testing (ROTEM, TEG and Sonoclot systems) (DG13)

Evidence-based recommendations on viscoelastometric point-of-care testing (ROTEM, TEG and Sonoclot systems) to detect, manage and monitor haemostasis

Diagnostics guidance Published August 2014

Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment (DG16)

Evidence-based recommendations on the My5-FU assay for guiding dose adjustment for fluorouracil chemotherapy

Diagnostics guidance Published December 2014

High-sensitivity troponin for the early rule out of acute myocardial infarction

In development [GID-DG10035] Expected publication date: 26 August 2020

Diagnostics guidance In development

PredictSURE-IBD and IBDX to guide personalised treatment of Crohn's disease

In development [GID-DG10029] Expected publication date: 08 July 2020

Diagnostics guidance In development

Testing strategies for Lynch syndrome in people with endometrial cancer

In development [GID-DG10033] Expected publication date: 29 July 2020

Diagnostics guidance In development

QAngio XA 3D/ QFR and CAAS vFFR imaging software for assessing the functional significance of coronary obstructions during invasive coronary angiography

In development [GID-DG10034] Expected publication date: 30 September 2020

Diagnostics guidance In development

Implantable cardiac monitors to detect atrial fibrillation after cryptogenic stroke

In development [GID-DG10023] Expected publication date: TBC

Diagnostics guidance In development

Lenalidomide for previously treated follicular lymphoma and marginal zone lymphoma [ID1374]

In development [GID-TA10323] Expected publication date: 01 April 2020

Technology appraisal guidance In development

Platelet-rich plasma injections for knee osteoarthritis (IPG637)

Evidence-based recommendations on platelet-rich plasma injections for knee osteoarthritis in adults (deterioration of the articular cartilage and menisci)

Interventional procedures guidance Published January 2019

Low-level laser therapy for preventing or treating oral mucositis caused by radiotherapy or chemotherapy (IPG615)

Evidence-based recommendations on low-level laser therapy for preventing or treating oral mucositis caused by radiotherapy or chemotherapy

Interventional procedures guidance Published May 2018

Artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure (IPG602)

Evidence-based recommendations on artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure

Interventional procedures guidance Published December 2017

Subcutaneous implantable cardioverter defibrillator insertion for preventing sudden cardiac death (IPG603)

Evidence-based recommendations on subcutaneous implantable cardioverter defibrillator insertion for preventing sudden cardiac death

Interventional procedures guidance Published December 2017

Transvaginal mesh repair of anterior or posterior vaginal wall prolapse (IPG599)

Evidence-based recommendations on transvaginal mesh repair of anterior or posterior vaginal wall prolapse

Interventional procedures guidance Published December 2017

Low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures (IPG623)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of delayed-union and non-union fractures

Interventional procedures guidance Published July 2018

Low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk of non-healing (IPG622)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of fresh fractures at high risk of non-healing

Interventional procedures guidance Published July 2018

Low-intensity pulsed ultrasound to promote healing of fresh fractures at low risk of non-healing (IPG621)

Evidence-based recommendations on low-intensity pulsed ultrasound (LIPUS) to promote healing of fresh fractures at low risk of non-healing in adults

Interventional procedures guidance Published July 2018

Transaxial interbody lumbosacral fusion for severe chronic low back pain (IPG620)

Evidence-based recommendations on transaxial interbody lumbosacral fusion for low back pain in adults

Interventional procedures guidance Published July 2018

Superior capsular augmentation for massive rotator cuff tears (IPG619)

Evidence-based recommendations on superior capsular augmentation for massive rotator cuff (shoulder) tears

Interventional procedures guidance Published July 2018

Laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina (IPG608)

Evidence-based recommendations on laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina

Interventional procedures guidance Published March 2018

Mosaicplasty for symptomatic articular cartilage defects of the knee (IPG607)

Evidence-based recommendations on mosaicplasty for symptomatic articular cartilage defects of the knee (osteochondral autologous transfer mosaicplasty)

Interventional procedures guidance Published March 2018

Unilateral MRI-guided focused ultrasound thalamotomy for moderate to severe tremor in Parkinson's disease (IPG606)

Evidence-based recommendations on unilateral MRI-guided focused ultrasound thalamotomy for moderate to severe tremor in Parkinson’s disease in adults

Interventional procedures guidance Published February 2018

Aortic valve reconstruction with processed bovine pericardium (IPG604)

Evidence-based recommendations on aortic valve reconstruction with processed bovine pericardium (using new valve made from chemically treated cow pericardium)

Interventional procedures guidance Published February 2018

Endobronchial valve insertion to reduce lung volume in emphysema (IPG600)

Evidence-based recommendations on endobronchial valve insertion to reduce lung volume in emphysema

Interventional procedures guidance Published December 2017

Transcutaneous microwave ablation for severe primary axillary hyperhidrosis (IPG601)

Evidence-based recommendations on transcutaneous microwave ablation for severe primary axillary hyperhidrosis (excessive sweating) in adults

Interventional procedures guidance Published December 2017

Sutureless aortic valve replacement for aortic stenosis (IPG624)

Evidence-based recommendations on sutureless aortic valve replacement for aortic stenosis in adults

Interventional procedures guidance Published August 2018

Superior rectal artery embolisation for haemorrhoids (IPG627)

Evidence-based recommendations on superior rectal artery embolisation for haemorrhoids in adults

Interventional procedures guidance Published August 2018

Leadless cardiac pacemaker implantation for bradyarrhythmias (IPG626)

Evidence-based recommendations on leadless cardiac pacemaker implantation for bradyarrhythmias (an inserted device to help the heart beat at a normal rate)

Interventional procedures guidance Published August 2018

Transurethral water jet ablation for lower urinary tract symptoms caused by benign prostatic hyperplasia (IPG629)

Evidence-based recommendations on transurethral water jet ablation for lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH)

Interventional procedures guidance Published September 2018

Intravesical microwave hyperthermia and chemotherapy for non-muscle-invasive bladder cancer (IPG628)

Evidence-based recommendations on intravesical microwave hyperthermia and chemotherapy for non-muscle-invasive bladder cancer

Interventional procedures guidance Published September 2018

Direct C1 lateral mass screw for cervical spine stabilisation (IPG146)

Evidence-based recommendations on direct C1 lateral mass screw for cervical spine stabilisation (to treat atlantoaxial fusion in the neck)

Interventional procedures guidance Published December 2005

Photodynamic therapy for non-melanoma skin tumours (including premalignant and primary non-metastatic skin lesions) (IPG155)

Evidence-based recommendations on photodynamic therapy for non-melanoma skin tumours (including premalignant and primary non-metastatic skin lesions)

Interventional procedures guidance Published February 2006

Percutaneous radiofrequency ablation for atrial fibrillation (IPG168)

Evidence-based recommendations on percutaneous radiofrequency ablation for atrial fibrillation (AF)

Interventional procedures guidance Published April 2006

Percutaneous endoscopic colostomy (IPG161)

Evidence-based recommendations on percutaneous endoscopic colostomy (PEC)

Interventional procedures guidance Published March 2006

Endometrial cryotherapy for menorrhagia (IPG157)

Evidence-based recommendations on endometrial cryotherapy for menorrhagia (heavy periods/menstrual bleeding)

Interventional procedures guidance Published March 2006

Photorefractive (laser) surgery for the correction of refractive errors (IPG164)

Evidence-based recommendations on photorefractive (laser) surgery (LASIK, LASEK, PRK) to correct refractive errors (myopia/astigmatism/hyperopia/presbyopia)

Interventional procedures guidance Published March 2006

High dose rate brachytherapy for carcinoma of the cervix (IPG160)

Evidence-based recommendations on high dose rate brachytherapy for carinoma of the cervix (cervical cancer)

Interventional procedures guidance Published March 2006

Percutaneous endoscopic laser thoracic discectomy (IPG61)

Evidence-based recommendations on percutaneous endoscopic laser thoracic discectomy for treating symptomatic thoracic disc herniation (TDH/disc bulge)

Interventional procedures guidance Published May 2004

Thrombin injections for pseudoaneurysms (IPG60)

Evidence-based recommendations on thrombin injections for treating pseudoaneurysms (false aneurysms)

Interventional procedures guidance Published May 2004

Falloposcopy with coaxial catheter (IPG62)

Evidence-based recommendations on falloposcopy with coaxial catheter for investigating and treating subfertility in women

Interventional procedures guidance Published June 2004

Balloon dilatation of pulmonary valve stenosis (IPG67)

Evidence-based recommendations on balloon dilatation for treating pulmonary valve stenosis (PVS)

Interventional procedures guidance Published June 2004

Artificial anal sphincter implantation (IPG66)

Evidence-based recommendations on artificial anal sphincter implantation for treating faecal incontinence

Interventional procedures guidance Published June 2004