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  1. Hypersexuality: fluoxetine (ESUOM46)

    Summary of the evidence on fluoxetine for treating hypersexuality to inform local NHS planning and decision-making

  2. Type 2 diabetes: dulaglutide (ESNM59)

    Summary of the evidence on dulaglutide for treating type 2 diabetes to inform local NHS planning and decision-making

  3. Digital ulcers: sildenafil (ESUOM42)

    Summary of the evidence on sildenafil for managing digital ulcers to inform local NHS planning and decision-making

  4. Minocycline (KTT11)

    The key therapeutic topic minocycline has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance .

  5. Laxatives (KTT1)

    The key therapeutic topic laxatives has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance .

  6. Three-day courses of antibiotics for uncomplicated urinary tract infection (KTT10)

    The key therapeutic topic 3-day courses of antibiotics for uncomplicated urinary tract infection has been retired from the 2017 update of medicines optimisation: key therapeutic topics. Key points have been incorporated into the antimicrobial stewardship topic. See the key therapeutic topic antimicrobial stewardship: prescribing antibiotics for more information.