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Community-based models of flu vaccination:- What models of community-based flu vaccination provision (for example, community pharmacies, community nursing and midwifery teams and outreach services) are effective and cost-effective for increasing uptake in eligible groups?

Recommendation ID NG103/5 Question Community-based models of flu vaccination:- What models of community-based flu vaccination provision

Research recommendation Published December 2018

Underserved groups:- What are the most effective and cost-effective ways of reaching underserved groups and removing barriers to access in order to increase their uptake of flu vaccination?

Recommendation ID NG103/2 Question Underserved groups:- What are the most effective and cost-effective ways of reaching underserved groups

Research recommendation Published December 2018

People in eligible groups:- What are the important messages and how should they be tailored and delivered to encourage and sustain flu vaccination uptake in eligible groups?

Recommendation ID NG103/1 Question People in eligible groups:- What are the important messages and how should they be tailored and delivered

Research recommendation Published December 2018

Addressing health inequalities:- What are the barriers to and facilitators for increasing access to community pharmacy services by underserved groups? How should health and wellbeing interventions be tailored to increase service uptake in underserved groups?

Recommendation ID NG102/3 Question Addressing health inequalities:- What are the barriers to and facilitators for increasing access to community

Research recommendation Published December 2018

Referral within a formal care pathway:- Is referral from a community pharmacy within a formal local care pathway framework more effective and cost effective than signposting alone in improving access to, and uptake of, services by underserved groups and the general population?

Recommendation ID NG102/1 Question Referral within a formal care pathway:- Is referral from a community pharmacy within a formal local care

Research recommendation Published December 2018

Carers:- In what context is it cost effective to increase uptake of flu vaccination among carers?

Recommendation ID NG103/3 Question Carers:- In what context is it cost effective to increase uptake of flu vaccination among carers?

Research recommendation Published December 2018

Further research in superior rectal artery embolisation for haemorrhoids should report details of patient selection, and follow-up efficacy (including symptom relief), need for subsequent treatments, quality of life and safety outcomes for at least 1 year.

Recommendation ID IPG627/1 Question Further research in superior rectal artery embolisation for haemorrhoids should report details of patient

Research recommendation Published December 2018

Opt-out strategies for front-line health and social care staff:- Are opt-out strategies effective and cost effective at increasing uptake of flu vaccination among front-line health and social care staff?

Recommendation ID NG103/4 Question Opt-out strategies for front-line health and social care staff:- Are opt-out strategies effective and

Research recommendation Published December 2018

Adjuvant bisphosphonate therapy:- Which groups of people with early and locally advanced breast cancer would benefit from the use of adjuvant bisphosphonates?

Recommendation ID NG101/2 Question Adjuvant bisphosphonate therapy:- Which groups of people with early and locally advanced breast cancer

Research recommendation Published December 2018

Surgery to the breast:- What is the optimum tumour-free margin width after breast-conserving surgery for women with ductal carcinoma in situ (DCIS) and invasive breast cancer?

Recommendation ID NG101/1 Question Surgery to the breast:- What is the optimum tumour-free margin width after breast-conserving surgery

Research recommendation Published December 2018

Case management:- What is the effectiveness and cost effectiveness of high-intensity case management compared with usual care on quality of life (for the person living with dementia and for their carers) and the timing of entry to long-term care?

Recommendation ID NG97/1 Question Case management:- What is the effectiveness and cost effectiveness of high-intensity case management compared

Research recommendation Published December 2018

Staff training:- What is the cost effectiveness of using a dementia-specific addition to the Care Certificate for community staff, including dementia-specific elements on managing anxiety, communication, nutritional status and personal care?

Recommendation ID NG97/2 Question Staff training:- What is the cost effectiveness of using a dementia-specific addition to the Care Certificate

Research recommendation Published December 2018

Monitoring and follow-up for adults with hearing loss:- What is the clinical and cost effectiveness of monitoring and follow-up for adults with hearing loss post-intervention compared with usual care?

Recommendation ID NG98/5 Question Monitoring and follow-up for adults with hearing loss:- What is the clinical and cost effectiveness of

Research recommendation Published December 2018

Earwax:- What is the clinical and cost effectiveness of microsuction compared with irrigation to remove earwax?

Recommendation ID NG98/2 Question Earwax:- What is the clinical and cost effectiveness of microsuction compared with irrigation to remove earwax

Research recommendation Published December 2018

Care and support planning:- What are the most effective methods of care planning for people who do not have regular contact with an informal carer?

Recommendation ID NG97/5 Question Care and support planning:- What are the most effective methods of care planning for people who do not

Research recommendation Published December 2018

Managing delirium superimposed on dementia:- What are the most clinically and cost-effective non-pharmacological interventions for helping the long-term recovery of people with delirium superimposed on dementia?

Recommendation ID NG97/4 Question Managing delirium superimposed on dementia:- What are the most clinically and cost-effective non-pharmacological

Research recommendation Published December 2018

Use of hearing aids and incidence of dementia:- In adults with hearing loss, does the use of hearing aids reduce the incidence of dementia?

Recommendation ID NG98/3 Question Use of hearing aids and incidence of dementia:- In adults with hearing loss, does the use of hearing aids

Research recommendation Published December 2018

Anticholinergic burden:- Does actively reducing anticholinergic burden in people living with dementia improve cognitive outcomes compared with usual care?

Recommendation ID NG72/3 Question Anticholinergic burden:- Does actively reducing anticholinergic burden in people living with dementia

Research recommendation Published December 2018

Supporting family members, carers and staff:- What types of services or approaches are effective in supporting family members, carers and staffto be resilient and able to provide care and support to people with a learning disability and behaviour that challenges?

Recommendation ID NG93/2 Question Supporting family members, carers and staff:- What types of services or approaches are effective in supporting

Research recommendation Published November 2018

Carbon monoxide monitoring:- What is the validity of different thresholds of carbon monoxide in exhaled breath as markers of quitting, based on diagnostic review and modelling?

Recommendation ID NG92/2 Question Carbon monoxide monitoring:- What is the validity of different thresholds of carbon monoxide in exhaled

Research recommendation Published November 2018

Models of supported living:- What is the effectiveness and cost effectiveness of models of shared, supported living, such as Shared Lives?What are the views and experiences of people sharing their home and people who live with themunder programmes such as Shared Lives?

Recommendation ID NG93/3 Question Models of supported living:- What is the effectiveness and cost effectiveness of models of shared, supported

Research recommendation Published November 2018

Interaction between behavioural and environmental interventions:- What is the effectiveness and cost effectiveness of interventions to change the environment alone, compared with interventions to change the environment that are supported by interventions to change people's behaviour?

Recommendation ID NG90/6 Question Interaction between behavioural and environmental interventions:- What is the effectiveness and cost effectiveness

Research recommendation Published November 2018

Duration of prophylaxis for elective total hip replacement surgery:- What is the clinical and cost effectiveness of standard versus extended duration pharmacological prophylaxis for preventing VTE in people undergoing elective total hip replacement surgery?

Recommendation ID NG89/5 Question Duration of prophylaxis for elective total hip replacement surgery:- What is the clinical and cost effectiveness

Research recommendation Published November 2018

Direct oral anticoagulants for people with lower limb immobilisation:- What is the clinical and cost effectiveness of direct oral anticoagulants for preventing VTE in people with lower limb immobilisation?

Recommendation ID NG89/3 Question Direct oral anticoagulants for people with lower limb immobilisation:- What is the clinical and cost effectiveness

Research recommendation Published November 2018

Risk assessment:- What is the accuracy of individual risk assessment tools in predicting the risk of venousthromboembolism (VTE) and risk of bleeding in people admitted to hospital?

Recommendation ID NG89/1 Question Risk assessment:- What is the accuracy of individual risk assessment tools in predicting the risk of

Research recommendation Published November 2018

Digital media:- How effective and cost effective are stop smoking interventions delivered using web-basedpackages or apps?

Recommendation ID NG92/1 Question Digital media:- How effective and cost effective are stop smoking interventions delivered using web-basedpackages

Research recommendation Published November 2018

Changes to public open spaces:- How effective and cost effective are environmental changes to public open spaces (including blue, green and grey spaces) in creating and sustaining an increase in physical activity at a population level?

Recommendation ID NG90/2 Question Changes to public open spaces:- How effective and cost effective are environmental changes to public open

Research recommendation Published November 2018

Public transport provision and ticketing:- How effective and cost effective are changes to public transport provision and ticketing in creating and sustaining an increase in physical activity at a population level?

Recommendation ID NG90/1 Question Public transport provision and ticketing:- How effective and cost effective are changes to public transport

Research recommendation Published November 2018

Models of care and support at home:- What is the effectiveness and cost effectiveness of care and support models (for example, assistive technology) for people growing older with learning disabilities to enable them to live in the family home?

Recommendation ID NG96/1 Question Models of care and support at home:- What is the effectiveness and cost effectiveness of care and support

Research recommendation Published November 2018

Seroprevalence of Lyme disease-specific antibodies and other tick-borne infections in the UK population:- What is the current seroprevalence of Lyme disease-specific antibodies and other tick-borne infections in people in the UK?

Recommendation ID NG95/3 Question Seroprevalence of Lyme disease-specific antibodies and other tick-borne infections in the UK population:- What

Research recommendation Published November 2018

Antimicrobial management of Lyme disease:- What are the most clinically and cost-effective treatment options for different clinical presentations of Lyme disease in the UK?

Recommendation ID NG95/4 Question Antimicrobial management of Lyme disease:- What are the most clinically and cost-effective treatment options

Research recommendation Published November 2018

Clinical epidemiology of Lyme disease in the UK:- What are the incidence, presenting features, management and outcome of Lyme disease in the UK?

Recommendation ID NG95/2 Question Clinical epidemiology of Lyme disease in the UK:- What are the incidence, presenting features, management

Research recommendation Published November 2018