Updating results

Improving adherence to asthma medication:- What are the most clinically and cost-effective strategies to improve medicines adherence in adults, young people and children with asthma who are non-adherent to prescribed medicines?

Recommendation ID NG80/10 Question Improving adherence to asthma medication:- What are the most clinically and cost-effective strategies

Research recommendation Published October 2018

Further research is recommended to assess the diagnostic accuracy of the tests included in this assessment when used in combination; for example sequentially.

Recommendation ID DG31/3 Question Further research is recommended to assess the diagnostic accuracy of the tests included in this assessment

Research recommendation Published October 2018

Further research is recommended to assess:- inter-observer reproducibility of tests involving ultrasound scans (the ADNEX model and Simple Rules)- changes in clinical management based on test results from the ADNEX model, Overa (MIA2G), ROMA and Simple Rules.

Recommendation ID DG31/2 Question Further research is recommended to assess:- inter-observer reproducibility of tests involving ultrasound

Research recommendation Published October 2018

Decreasing pharmacological treatment:- In adults, young people and children with well-controlled asthma, what are the objective measurements and prognostic factors that indicate that a decrease in regular maintenance treatment is appropriate?

Recommendation ID NG80/9 Question Decreasing pharmacological treatment:- In adults, young people and children with well-controlled asthma

Research recommendation Published October 2018

Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does enhanced developmental support and surveillance improve outcomes for the parents and carers of children born preterm?

Recommendation ID NG72/5 Question Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does

Research recommendation Published October 2018

Trials that evaluate utility values (using generic preference-based measures) in children and young people with severe psoriasis are needed to better inform future cost–utility analyses.

Recommendation ID TA455/1 Question Trials that evaluate utility values (using generic preference-based measures) in children and young people

Research recommendation Published October 2018

Rapid eye movement sleep behaviour disorder treatment:- What is the best first-line treatment for rapid eye movement sleep behaviour disorder (RBD) in people with Parkinson's disease?

Recommendation ID NG71/4 Question Rapid eye movement sleep behaviour disorder treatment:- What is the best first-line treatment for rapid

Research recommendation Published October 2018

Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared with atypical antipsychotic drugs for treating psychotic symptoms (particularly hallucinations and delusions) associated with Parkinson's disease?

Recommendation ID NG71/3 Question Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared

Research recommendation Published October 2018

Physiotherapy:- Does physiotherapy started early in the course of Parkinson's disease, as opposed to after motor symptom onset, confer benefits in terms of delaying symptom onset and/or reducing severity?

Recommendation ID NG71/5 Question Physiotherapy:- Does physiotherapy started early in the course of Parkinson's disease, as opposed to after

Research recommendation Published October 2018

Team composition for home-based intermediate care:- How effective and cost effective are different approaches, in terms of team structure and composition, to providing home-based intermediate care for adults?

Recommendation ID NG74/2 Question Team composition for home-based intermediate care:- How effective and cost effective are different approaches

Research recommendation Published October 2018

Support needs of parents:- What are the experiences and concerns of parents of children with faltering growth?

Recommendation ID NG75/5 Question Support needs of parents:- What are the experiences and concerns of parents of children with faltering

Research recommendation Published October 2018

Support for black and minority ethnic groups:- How effective and cost effective are different approaches to supporting people from black and minority ethnic groups using intermediate care?

Recommendation ID NG74/8 Question Support for black and minority ethnic groups:- How effective and cost effective are different approaches

Research recommendation Published October 2018

Reablement:- How effective and cost effective are repeated periods of reablement, and reablement that lasts longer than 6 weeks?

Recommendation ID NG74/5 Question Reablement:- How effective and cost effective are repeated periods of reablement, and reablement that

Research recommendation Published October 2018

Pain management programmes:- Are pain management programmes a clinically and cost-effective intervention for women with endometriosis?

Recommendation ID NG73/1 Question Pain management programmes:- Are pain management programmes a clinically and cost-effective intervention

Research recommendation Published October 2018

Optimal time between referral and starting intermediate care:- What is the optimal time between referral to and starting intermediate care in terms of effectiveness and cost effectiveness and in terms of people's experiences?

Recommendation ID NG74/1 Question Optimal time between referral and starting intermediate care:- What is the optimal time between referral

Research recommendation Published October 2018

Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise) effective, compared with no specialist lifestyle interventions, for women with endometriosis?

Recommendation ID NG73/3 Question Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise)

Research recommendation Published October 2018

Laparoscopic treatment of peritoneal endometriosis (excision or ablation):- Is laparoscopic treatment (excision or ablation) of peritoneal disease in isolation effective formanaging endometriosis-related pain?

Recommendation ID NG73/2 Question Laparoscopic treatment of peritoneal endometriosis (excision or ablation):- Is laparoscopic treatment

Research recommendation Published October 2018

Information and support:- What information and support interventions are effective to help women with endometriosis deal with their symptoms and improve their quality of lives?

Recommendation ID NG73/4 Question Information and support:- What information and support interventions are effective to help women with

Research recommendation Published October 2018

High energy liquid feed supplements:- Do high energy liquid feed supplements improve growth in children with faltering growth?

Recommendation ID NG75/1 Question High energy liquid feed supplements:- Do high energy liquid feed supplements improve growth in children

Research recommendation Published October 2018

Further research should give details of patient selection, patient-reported outcomes and long-term effects including survival and quality of life. NICE may update the guidance on publication of further evidence.

Recommendation ID IPG594/1 Question Further research should give details of patient selection, patient-reported outcomes and long-term effects

Research recommendation Published October 2018

Frequency of monitoring:- How frequently should children be measured to identify faltering growth?

Recommendation ID NG75/4 Question Frequency of monitoring:- How frequently should children be measured to identify faltering growth?

Research recommendation Published October 2018

Feeding interventions for the management of neonatal weight loss:- What is the effectiveness of feeding interventions compared with usual care/advice for breastfedneonates (up to 28 days old) with weight loss of greater than 10%?

Recommendation ID NG75/2 Question Feeding interventions for the management of neonatal weight loss:- What is the effectiveness of feeding

Research recommendation Published October 2018

Duration and intensity of home-based intermediate care:- How effective and cost effective are different approaches, in terms of duration and intensity, to providing home-based intermediate care for adults?

Recommendation ID NG74/7 Question Duration and intensity of home-based intermediate care:- How effective and cost effective are different

Research recommendation Published October 2018

Dementia care:- How effective and cost effective is intermediate care including reablement for supporting people living with dementia?

Recommendation ID NG74/4 Question Dementia care:- How effective and cost effective is intermediate care including reablement for supporting

Research recommendation Published October 2018

Crisis response:- What are the barriers and facilitators to providing an effective and cost effective crisis response service, with particular reference to different models for structuring delivery of this service?

Recommendation ID NG74/3 Question Crisis response:- What are the barriers and facilitators to providing an effective and cost effective

Research recommendation Published October 2018

Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual care/advice for children with faltering growth?

Recommendation ID NG75/3 Question Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual

Research recommendation Published October 2018

A single point of access for intermediate care:- How effective and cost effective is introducing a single point of access to intermediate care?

Recommendation ID NG74/6 Question A single point of access for intermediate care:- How effective and cost effective is introducing a single

Research recommendation Published October 2018

Vegetation and street trees:- What factors influence how vegetation and street trees affect urban air quality?

Recommendation ID NG70/1 Question Vegetation and street trees:- What factors influence how vegetation and street trees affect urban air

Research recommendation Published October 2018

Telematics:- How can information about driving style gathered from telematics devices and other technologies (such as apps or in-car global positioning systems) be used to reduce individual fuel consumption and vehicle emissions?

Recommendation ID NG70/4 Question Telematics:- How can information about driving style gathered from telematics devices and other technologies (such

Research recommendation Published October 2018

Promoting a shift to zero- and low-emission travel:- What methods are effective and cost effective at promoting a shift to zero- and low-emission modes of travel, including active travel?

Recommendation ID NG70/2 Question Promoting a shift to zero- and low-emission travel:- What methods are effective and cost effective at

Research recommendation Published October 2018

NICE encourages the company, NHS England and treatment centres to collect more evidence, particularly on the longer-term benefits and costs of eliglustat and enzyme replacement therapy for treating type 1 Gaucher disease.

Recommendation ID HST5/1 Question NICE encourages the company, NHS England and treatment centres to collect more evidence, particularly

Research recommendation Published October 2018

Exposure to air pollution using different modes of transport How does altering a person's mode of transport and route affect their personal exposure to air pollution?

Recommendation ID NG70/6 Question Exposure to air pollution using different modes of transport How does altering a person's mode of transport

Research recommendation Published October 2018

Clean air zones:- How do different elements of a clean air zone interact to improve air quality and what is the overall effect on people's health?

Recommendation ID NG70/3 Question Clean air zones:- How do different elements of a clean air zone interact to improve air quality and what

Research recommendation Published October 2018

Clinicians are encouraged to collect long-term data on clinical outcomes and patient-reported quality-of-life outcomes using validated scales. NICE may update the guidance on publication of further evidence into infracoccygeal sacropexy using mesh to repair uterine prolapse.

Recommendation ID IPG582/1 Question Clinicians are encouraged to collect long-term data on clinical outcomes and patient-reported quality-of-life

Research recommendation Published October 2018