Updating results

Spinal fusion:- Should people with low back pain be offered spinal fusion as a surgical option?

Recommendation ID NG59/5 Question Spinal fusion:- Should people with low back pain be offered spinal fusion as a surgical option? Any

Research recommendation Published February 2017

Pharmacological therapies:- What is the clinical and cost effectiveness of codeine with and without paracetamol for the acute management of low back pain?

Recommendation ID NG59/2 Question Pharmacological therapies:- What is the clinical and cost effectiveness of codeine with and without paracetamol

Research recommendation Published February 2017

Radiofrequency denervation:- What is the clinical and cost effectiveness of radiofrequency denervation for chronic low back pain in the long term?

Recommendation ID NG59/3 Question Radiofrequency denervation:- What is the clinical and cost effectiveness of radiofrequency denervation

Research recommendation Published February 2017

Pharmacological therapies:- What is the clinical and cost effectiveness of benzodiazepines for the acute management of low back pain?

Recommendation ID NG59/1 Question Pharmacological therapies:- What is the clinical and cost effectiveness of benzodiazepines for the acute

Research recommendation Published February 2017

Access to medicines:- Does the use of directly observed supply of named high-risk medicines (that is, not supplying the medicines to people to hold in-possession), reduce diversion, abuse and non-adherence?

Recommendation ID NG57/5 Question Access to medicines:- Does the use of directly observed supply of named high-risk medicines (that is,

Research recommendation Published February 2017

Assessment tools for health promotion:- What are the most effective tools to determine the health promotion needs of people in prison?

Recommendation ID NG57/4 Question Assessment tools for health promotion:- What are the most effective tools to determine the health promotion

Research recommendation Published February 2017

Barriers and facilitators:- What are the barriers and facilitators for young people and adults with coexisting severe mental illness and substance misuse to obtain an optimal service (including optimal time frame for delivering interventions) to meet their needs and enable their recovery?

Recommendation ID NG58/4 Question Barriers and facilitators:- What are the barriers and facilitators for young people and adults with coexisting

Research recommendation Published February 2017

Care pathway:- In the UK, what is the optimal care pathway for young people and adults with coexisting severe mental illness and substance misuse?

Recommendation ID NG58/5 Question Care pathway:- In the UK, what is the optimal care pathway for young people and adults with coexisting

Research recommendation Published February 2017

Costing tool:- Which elements of health, social care or other support services work best at a local level and provide the best 'value for money' to address the needs of young people and adults with coexisting severe mental illness and substance misuse?

Recommendation ID NG58/3 Question Costing tool:- Which elements of health, social care or other support services work best at a local level

Research recommendation Published February 2017

Promoting health and wellbeing:- What is the most effective method for delivering health promotion activities and who should lead them (peers or professionals)?

Recommendation ID NG57/3 Question Promoting health and wellbeing:- What is the most effective method for delivering health promotion activities

Research recommendation Published February 2017

Needs assessment:- In the UK, how prevalent is coexisting severe mental illness with substance misuse and what are the physical health, social care, housing or other support needs of people with this diagnosis?

Recommendation ID NG58/1 Question Needs assessment:- In the UK, how prevalent is coexisting severe mental illness with substance misuse

Research recommendation Published February 2017

NICE encourages further research into single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) for treating morbid obesity, particularly research examining long-term outcomes. NICE may update the guidance on publication of further evidence.

Recommendation ID IPG569/1 Question NICE encourages further research into single-anastomosis duodeno-ileal bypass with sleeve gastrectomy

Research recommendation Published February 2017

Further research is recommended on alternative postpartum testing strategies that do not include cord blood typing of all babies born to rhesus-D (D) negative women.

Recommendation ID DG25/1 Question Further research is recommended on alternative postpartum testing strategies that do not include cord

Research recommendation Published February 2017

What are the most effective and cost-effective interventions to maintain and improve the health and wellbeing of older employees?

Recommendation ID NG13/5 Question What are the most effective and cost-effective interventions to maintain and improve the health and wellbeing

Research recommendation Published November 2016

What are the most effective and cost-effective interventions to help older employees plan and prepare for retirement?

Recommendation ID NG13/7 Question What are the most effective and cost-effective interventions to help older employees plan and prepare

Research recommendation Published November 2016

What are the most effective and cost-effective interventions to help older employees stay in or re-enter work? For example, to overcome the problems of a change in job specification?

Recommendation ID NG13/6 Question What are the most effective and cost-effective interventions to help older employees stay in or re-enter

Research recommendation Published November 2016

What are the most effective and cost-effective interventions to challenge stereotypes and change employers' and workforce attitudes towards older employees?

Recommendation ID NG13/8 Question What are the most effective and cost-effective interventions to challenge stereotypes and change employers'

Research recommendation Published November 2016

Stopping preventive medicines:- What is the clinical and cost effectiveness of stopping preventive medicines in people with multimorbidity who may not benefit from continuing them?

Recommendation ID NG56/3 Question Stopping preventive medicines:- What is the clinical and cost effectiveness of stopping preventive medicines

Research recommendation Published October 2016

Holistic assessment in the community:- What is the clinical and cost effectiveness of a community holistic assessment and intervention for people living with high levels of multimorbidity?

Recommendation ID NG56/2 Question Holistic assessment in the community:- What is the clinical and cost effectiveness of a community holistic

Research recommendation Published October 2016

Predicting life expectancy:- Is it possible to analyse primary care data to identify characteristics that affect life expectancy and to develop algorithms and prediction tools for patients and healthcare providers to predict reduced life expectancy?

Recommendation ID NG56/4 Question Predicting life expectancy:- Is it possible to analyse primary care data to identify characteristics that

Research recommendation Published October 2016

Organisation of care:- What is the clinical and cost effectiveness of alternative approaches to organising primary care compared with usual care for people with multimorbidity?

Recommendation ID NG56/1 Question Organisation of care:- What is the clinical and cost effectiveness of alternative approaches to organising

Research recommendation Published October 2016

Assessment models for different groups of children and young people:- How effective are the models currently used for assessing the needs of, and level of risk for, children and young people from different population groups who display harmful sexual behaviour?

Recommendation ID NG55/5 Question Assessment models for different groups of children and young people:- How effective are the models currently

Research recommendation Published October 2016

Care and support for people with dementia:- What is the effect of specific interventions to support people with dementia during transition between inpatient mental health settings and community or care home settings?

Recommendation ID NG53/1 Question Care and support for people with dementia:- What is the effect of specific interventions to support people

Research recommendation Published October 2016

Early interventions to prevent problems escalating:- What interventions are effective in diverting children and young people away from further harmful sexual behaviour before a legal response is needed?

Recommendation ID NG55/4 Question Early interventions to prevent problems escalating:- What interventions are effective in diverting children

Research recommendation Published October 2016

Electronic media:- How does the use of electronic media affect harmful sexual behaviour?

Recommendation ID NG55/6 Question Electronic media:- How does the use of electronic media affect harmful sexual behaviour? Any explanatory

Research recommendation Published October 2016

Effective interventions for the families and carers of children and young people displaying harmful sexual behaviour:- What type of therapeutic interventions are effective when working with the family and carers of children and young people who display harmful sexual behaviour?

Recommendation ID NG55/3 Question Effective interventions for the families and carers of children and young people displaying harmful sexual

Research recommendation Published October 2016

The experiences of people with learning disabilities and mental health problems in services:- What experience do people with learning disabilities have of services designed to prevent and treat mental health problems and how does this relate to clinical outcomes?

Recommendation ID NG54/6 Question The experiences of people with learning disabilities and mental health problems in services:- What experience

Research recommendation Published October 2016

Psychosocial interventions for people with more severe learning disabilities:- For people with more severe learning disabilities, what is the clinical and cost effectiveness of psychosocial interventions to treat mental health problems?

Recommendation ID NG54/5 Question Psychosocial interventions for people with more severe learning disabilities:- For people with more severe

Research recommendation Published October 2016

Pharmacological interventions for anxiety disorders in people with learning disabilities who have autism:- What is the clinical and cost effectiveness and safety of pharmacological interventions for anxiety disorders in people with learning disabilities who have autism?

Recommendation ID NG54/4 Question Pharmacological interventions for anxiety disorders in people with learning disabilities who have autism:-

Research recommendation Published October 2016

Develop case identification tools for common mental health problems:- Develop or adapt reliable and valid tools for the case identification of common mental health problems in people with learning disabilities, for routine use in primary care, social care and education settings.

Recommendation ID NG54/1 Question Develop case identification tools for common mental health problems:- Develop or adapt reliable and valid

Research recommendation Published October 2016

Effective interventions for children and young people displaying harmful sexual behaviour:- What interventions are effective with children and young people displaying harmful sexual behaviour?

Recommendation ID NG55/2 Question Effective interventions for children and young people displaying harmful sexual behaviour:- What interventions

Research recommendation Published October 2016

Assessing the risk of cirrhosis:- Development of a risk tool to identify people at risk of cirrhosis.

Recommendation ID NG50/1 Question Assessing the risk of cirrhosis:- Development of a risk tool to identify people at risk of cirrhosis.

Research recommendation Published August 2016

A complex service evaluation of implementation of NICE Sepsis guideline:- What effect will the NICE sepsis guideline have on patient care processes and outcomes in the UK over the next 5 years?

Recommendation ID NG51/2 Question A complex service evaluation of implementation of NICE Sepsis guideline:- What effect will the NICE sepsis

Research recommendation Published August 2016

Treating small oesophageal varices:- Do non-selective beta-blockers improve survival and prevent first variceal bleeds in people with cirrhosis that is associated with small oesophageal varices?

Recommendation ID NG50/2 Question Treating small oesophageal varices:- Do non-selective beta-blockers improve survival and prevent first

Research recommendation Published August 2016

Transjugular intrahepatic portosystemic shunt:- What is the quality of life in people who have had a transjugular intrahepatic portosystemic shunt (TIPS)?

Recommendation ID NG50/4 Question Transjugular intrahepatic portosystemic shunt:- What is the quality of life in people who have had a transjugular

Research recommendation Published August 2016

Use of biomarkers to diagnose and initiate treatment:- What is the clinical and cost effectiveness of procalcitonin (PCT) point-of-care tests at initial triage for diagnosis of serious infection and the initiation of appropriate antibiotic therapy?

Recommendation ID NG51/3 Question Use of biomarkers to diagnose and initiate treatment:- What is the clinical and cost effectiveness of

Research recommendation Published August 2016

Derivation of clinical decision rules in suspected sepsis:- Is it possible to derive and validate a set of clinical decision rules or a predictive tool to rule outsepsis which can be applied to patients presenting to hospital; with suspected sepsis?

Recommendation ID NG51/5 Question Derivation of clinical decision rules in suspected sepsis:- Is it possible to derive and validate a set

Research recommendation Published August 2016

Epidemiological study on presentation and management of sepsis in England:- What is the incidence, presentation and management of sepsis in the United Kingdom?

Recommendation ID NG51/1 Question Epidemiological study on presentation and management of sepsis in England:- What is the incidence, presentation

Research recommendation Published August 2016