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  1. Management of anaemia of chronic kidney disease with concurrent illness:- What is the optimal management (in terms of clinical and cost effectiveness) of anaemia of chronic kidney disease (CKD) in patients who are receiving erythropoietic stimulating agents (ESAs) and have a significant concurrent acute infectious illness?

    Recommendation ID NG8/1 Question Management of anaemia of chronic kidney disease with concurrent illness:- What is the optimal management

  2. Management of smouldering myeloma:- Which combinations of FISH, molecular technologies, bone marrow plasma cell percentage, whole-body imaging, immunophenotype, serum-free light-chain levels or ratio, Hevylite, paraprotein levels, immunoparesis, and International Staging System (ISS) are most effective at risk stratification for people with smouldering myeloma? What is the comparative effectiveness of fixed duration treatment (with or without bone-directed therapy), continuous treatment (with or without bone-directed therapy) and no treatment (with or without bone-directed therapy) for people with smouldering myeloma?

    Recommendation ID NG35/3 Question Management of smouldering myeloma:- Which combinations of FISH, molecular technologies, bone marrow plasma

  3. Management of stable angina in people with evidence of ischaemia on non-invasive functional testing:- Do people with stable angina and evidence of reversible ischaemia on noninvasive functional testing who are on optimal drug treatment benefit from routine coronary angiography with a view to revascularisation?

    Recommendation ID CG126/2 Question Management of stable angina in people with evidence of ischaemia on non-invasive functional testing:-

  4. Management strategies to reduce the risk of symptomatic urinary tract infections:- In people with neurogenic lower urinary tract dysfunction, which management strategies (including the use of prophylactic antibiotics and various invasive and non-invasive techniques to aid bladder drainage) reduce the risk of symptomatic urinary tract infections?

    Recommendation ID CG148/3 Question Management strategies to reduce the risk of symptomatic urinary tract infections:- In people with neurogenic

  5. Managing behaviour that challenges in children and young people with autism:- Is a group-based parent training intervention for parents or carers of children and young people with autism clinically and cost effective in reducing early and emerging behaviour that challenges in the short- and medium-term compared with treatment as usual?

    Recommendation ID CG170/2 Question Managing behaviour that challenges in children and young people with autism:- Is a group-based parent

  6. Maternal request for Casarean Section (CS): What support or psychological interventions would be appropriate for women who have a fear of vaginal childbirth and request a CS? Interventions for evaluation could include: • support from a named member of the maternity team • continuity of carer • formal counselling • cognitive behavioural therapy. Outcomes could include: • mode of birth planned at term • psychological outcomes (postnatal depression, post-traumatic stress disorder, self-esteem, mother–infant bonding) • breastfeeding.

    Recommendation ID CG132/4 Question Maternal request for Casarean Section (CS): What support or psychological interventions would be appropriate