Recommendation ID NG135/4 Question How effective and cost effective are education-based alcohol interventions targeted at children and young
Recommendation ID NG135/2 Question How effective and cost effective are individual, compared with group, education-based interventions for
Recommendation ID NG130/1 Question In a mild-to-moderate first presentation or inflammatory exacerbation of proctitis that is resistant
Recommendation ID NG130/2 Question What is the effectiveness of oral tacrolimus and systemic (intramuscular/subcutaneous/oral) methotrexate
Recommendation ID NG130/3 Question What is the clinical and cost effectiveness of prednisolone, budesonide, and beclometasone in addition
Recommendation ID CG30/1 Question Few women use contraception perfectly (that is, exactly in accordance with the product instructions) and
Recommendation ID NG135/3 Question How effective and cost effective are universal, education-based alcohol interventions for children and
Recommendation ID CG30/3 Question In addition to individual circumstances and needs, a woman's choice and acceptance of LARC may be influenced
Recommendation ID NG135/1 Question What components of alcohol education delivery contribute to its effectiveness for children and young
Recommendation ID NG131/1 Question What is the most suitable surveillance protocol (including the role of digital rectal examination [DRE]
Recommendation ID DG35/1 Question The committee recommended further research to determine if using the lead‑I electrocardiogram (ECG) devices
Recommendation ID NG129/1 Question What are the benefits, risk and cost effectiveness of enteral nutrition in maintaining remission in the
Recommendation ID DG35/2 Question The committee recommended that data should be collected to evaluate the system impact of adopting the
Recommendation ID NG131/7 Question In patients with negative MRI (Likert score 1 or 2), what is the next best diagnostic investigation to
Recommendation ID NG130/4 Question What is the clinical and cost effectiveness of prednisolone compared with aminosalicylates for the induction
Recommendation ID NG130/5 Question What is the clinical and cost effectiveness of prednisolone plus an aminosalicylate compared with beclometasone
Recommendation ID NG130/6 Question What are the benefits, risks and cost effectiveness of methotrexate, ciclosporin, tacrolimus, adalimumab
Recommendation ID DG36/2 Question secondary research is recommended to understand the clinical validity of enzyme-linked immunosorbent assay
Recommendation ID DG36/3 Question Secondary research is recommended to understand the comparative performance of different ELISA tests for
Recommendation ID CG30/2 Question Most women will need to use contraception for more than 30 years. Patterns of contraceptive use vary with
Recommendation ID NG131/8 Question What is the effectiveness and cost effectiveness of different scheduling of zoledronic acid in the prevention
Recommendation ID DG36/1 Question Further primary research is recommended on the clinical effectiveness of using ELISA tests for therapeutic
Recommendation ID NG136/6 Question Which people with extreme hypertension (220/120 mmHg or higher) or emergency symptoms should be referred
Recommendation ID NG137/1 Question What is the most accurate prenatal screening marker for TAPS, including middle cerebral artery peak systolic
Recommendation ID NG33/3 Question For isoniazid-resistant TB, what is the most effective regimen for reducing mortality andmorbidity?
Recommendation ID NG33/5 Question For people with active, drug susceptible TB who experience treatment interruptions because of adverse
Recommendation ID NG33/1 Question In people with suspected TB, what is the relative clinical and cost effectiveness of universal andrisk-based
Recommendation ID NG136/2 Question ion (with or without type 2 diabetes), what are the appropriate risk and blood pressure thresholds for
Recommendation ID NG136/5 Question What is the clinical and cost effectiveness of relaxation therapies for managing primary hypertension
Recommendation ID NG33/4 Question What effects does isolation have on the quality of life of people being treated for TB? Any explanatory
Recommendation ID NG140/6 Question What is the effectiveness and safety of regimens using mifepristone and misoprostol for women who are
Recommendation ID NG140/4 Question For women who are having medical abortion between 10+1 and 12+0 weeks, what is the efficacy and acceptability
Recommendation ID NG136/4 Question Are there subgroups of people with hypertension who should start on dual therapy? Any explanatory
Recommendation ID TA599/1 Question The committee noted that there was no clinical evidence showing that having sodium zirconium cyclosilicate
Recommendation ID IPG657/1 Question Current evidence on the safety of ultrasound-guided high‑intensity transcutaneous focused ultrasound
Recommendation ID IPG653/1 Question Current evidence on the safety and efficacy of valve-in-valve transcatheter aortic valve implantation
Recommendation ID IPG656/1 Question The evidence on the safety of transurethral laser ablation for recurrent non-muscle-invasive bladder
Recommendation ID CG71/6 Question What is the utility of routine cardiovascular evaluation for asymptomatic people with FH? Any explanatory
Recommendation ID NG19/12 Question When is it safe to stop contact casting in the treatment of acute Charcot arthropathy? Any explanatory
Recommendation ID NG19/11 Question Which risk stratification tools can be used to predict the likelihood of Charcot arthropathy? Any
Recommendation ID NG1/2 Question What is the effectiveness and cost effectiveness of a trial of hydrolysed formula in formula‑fed infants
Recommendation ID CG137/5 Question What is the malformation rate and longer term neurodevelopmental outcome of children born to mothers
Recommendation ID NG19/10 Question What is the clinical effectiveness of maggot debridement therapy in the debridement of diabetic foot
Recommendation ID NG19/9 Question What is the clinical effectiveness of negative pressure wound therapy in the treatment of diabetic foot
Recommendation ID NG19/5 Question What is the clinical effectiveness of different dressing types in treating diabetic foot problems?
Recommendation ID CG184/3 Question What is the clinical effectiveness of double-dose PPIs in people with severe erosive reflux disease (Los
Recommendation ID NG142/2 Question Which of the electronic information-sharing systems perform best for the care of people approaching the
Recommendation ID CG137/2 Question What are the initial and add-on AEDs of choice in the treatment of the epilepsy syndromes with onset
Recommendation ID CG184/2 Question What is the effectiveness of laparoscopic fundoplication compared with medical management in people with
Recommendation ID CG71/4 Question What are the appropriate indications, effectiveness and safety of LDL apheresis in people with heterozygous