Updating results

Hysteroscopic removal of submucosal fibroids compared with other uterine-sparing treatments for HMB:- Is hysteroscopic removal of submucosal fibroids more effective and cost-effective than other uterine-sparing treatments for the management of HMB?

Recommendation ID NG88/4 Question Hysteroscopic removal of submucosal fibroids compared with other uterine-sparing treatments for HMB:- Is

Research recommendation Published November 2018

Effectiveness of the progestogen-only pill, injectable progestogens, or progestogen implants in alleviating HMB:- How effective are the progestogen-only pill, injectable progestogens or progestogen implants in alleviating HMB?

Recommendation ID NG88/2 Question Effectiveness of the progestogen-only pill, injectable progestogens, or progestogen implants in alleviating

Research recommendation Published November 2018

Further research on laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina should include details of patient selection and long-term outcomes.

Recommendation ID IPG608/1 Question Further research on laparoscopic mesh pectopexy for apical prolapse of the uterus or vagina should include

Research recommendation Published November 2018

Use of technology in providing care- What are the views and experiences of people who use adult social care services on assistive technologies?

Recommendation ID NG86/4 Question Use of technology in providing care- What are the views and experiences of people who use adult social

Research recommendation Published November 2018

Psychological support needs:- A qualitative study should be undertaken to evaluate information and support interventions to address psychological needs at different points in the care pathway for people with pancreatic cancer.

Recommendation ID NG85/5 Question Psychological support needs:- A qualitative study should be undertaken to evaluate information and support

Research recommendation Published November 2018

Neoadjuvant therapy:- Prospective randomised trials should be undertaken to compare preoperative (neoadjuvant) therapy with standard postoperative therapy in people with resectable pancreatic cancer.

Recommendation ID NG85/1 Question Neoadjuvant therapy:- Prospective randomised trials should be undertaken to compare preoperative (neoadjuvant)...

Research recommendation Published November 2018

Further research on unilateral MRI-guided focused ultrasound thalamotomy for moderate to severe tremor in Parkinson's disease, which could include randomised controlled trials, should address patient selection and report on long-term follow-up.

Recommendation ID IPG606/1 Question Further research on unilateral MRI-guided focused ultrasound thalamotomy for moderate to severe tremor

Research recommendation Published November 2018

Further research on aortic valve reconstruction with processed bovine pericardium should address patient selection and report long-term outcomes, particularly the durability of the valve.

Recommendation ID IPG604/1 Question Further research on aortic valve reconstruction with processed bovine pericardium should address patient

Research recommendation Published November 2018

Strategies to slow the progression of age-related macular degeneration (AMD):- What is the effectiveness of antioxidant and zinc supplements on AMD disease progression for people with early AMD at high risk of progression in the context of a randomised controlled trial?

Recommendation ID NG82/1 Question Strategies to slow the progression of age-related macular degeneration (AMD):- What is the effectiveness

Research recommendation Published November 2018

Stopping rules for antiangiogenic treatment for late AMD (wet):- When should anti-vascular endothelial growth factor (VEGF) treatment be suspended or stoppedin people with late AMD (wet)?

Recommendation ID NG82/3 Question Stopping rules for antiangiogenic treatment for late AMD (wet):- When should anti-vascular endothelial

Research recommendation Published November 2018

Self-monitoring strategies:- Does earlier detection of the incidence of late AMD (wet active) by self-monitoring in people diagnosed with early AMD, indeterminate AMD or late AMD (dry) lead to earlier treatment and better long-term outcomes?

Recommendation ID NG82/5 Question Self-monitoring strategies:- Does earlier detection of the incidence of late AMD (wet active) by self-monitoring

Research recommendation Published November 2018

Radical treatment of T1bN0 adenocarcinoma of the oesophagus:- What is the optimal treatment for T1bN0 adenocarcinoma of the oesophagus?

Recommendation ID NG83/2 Question Radical treatment of T1bN0 adenocarcinoma of the oesophagus:- What is the optimal treatment for T1bN0

Research recommendation Published November 2018

Radical treatment of squamous cell carcinoma of the oesophagus:- Does the addition of surgery to chemoradiotherapy improve disease-free and overall survival inpeople with squamous cell carcinoma of the oesophagus?

Recommendation ID NG83/1 Question Radical treatment of squamous cell carcinoma of the oesophagus:- Does the addition of surgery to chemoradiotherapy

Research recommendation Published November 2018

Nutritional support after radical surgery:- What is the optimal method of delivering nutritional support to adults after surgery with curative intent for oesophago-gastric cancer?

Recommendation ID NG83/3 Question Nutritional support after radical surgery:- What is the optimal method of delivering nutritional support

Research recommendation Published November 2018

Pain management:- A randomised trial should be undertaken comparing early endoscopic ultrasound-guided neurolytic coeliac plexus (EUS-guided NCP) interventions with on-demand EUS-guided NCP interventions in people with unresectable pancreatic cancer.

Recommendation ID NG85/4 Question Pain management:- A randomised trial should be undertaken comparing early endoscopic ultrasound-guided

Research recommendation Published November 2018

Jejunostomy support after radical surgery:- What is the effectiveness of long-term jejunostomy support compared to intensive dietary counselling and support along with symptom management for people having radical surgery for oesophago-gastric cancer?

Recommendation ID NG83/4 Question Jejunostomy support after radical surgery:- What is the effectiveness of long-term jejunostomy support

Research recommendation Published November 2018

Frequency of monitoring:- What is the long-term cost effectiveness, in terms of patient-relevant outcomes including bestcorrected visual acuity and quality of life, of different review frequencies/strategies for people at risk of progression to late AMD (wet active)?

Recommendation ID NG82/4 Question Frequency of monitoring:- What is the long-term cost effectiveness, in terms of patient-relevant outcomes

Research recommendation Published November 2018

Follow-up after treatment with curative intent:- Is the routine use of CT and tumour markers effective in detecting recurrent disease suitable for radical treatment in asymptomatic people who have had treatment for oesophago-gastric cancer with curative intent?

Recommendation ID NG83/5 Question Follow-up after treatment with curative intent:- Is the routine use of CT and tumour markers effective

Research recommendation Published November 2018

Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine assessment and monitoring of changes in pulmonary status in people with cystic fibrosis?

Recommendation ID NG78/3 Question Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine

Research recommendation Published November 2018

Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative vision- and health-related quality of life, and postoperative vision-related quality of life, health-related quality of life, and self-reported postoperative improvement?

Recommendation ID NG77/3 Question Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative

Research recommendation Published November 2018

Further research on high-intensity focused ultrasound for symptomatic breast fibroadenoma should include publication of patient-reported outcome measures and studies with long-term follow-up.

Recommendation ID IPG592 Question Further research on high-intensity focused ultrasound for symptomatic breast fibroadenoma should include

Research recommendation Published November 2018

Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung function in infants and children with cystic fibrosis?

Recommendation ID NG78/2 Question Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung

Research recommendation Published November 2018

NICE encourages further research into total artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure, including well matched comparative studies. NICE may update the guidance on publication of further evidence.

Recommendation ID IPG602/1 Question NICE encourages further research into total artificial heart implantation as a bridge to transplantation

Research recommendation Published October 2018

Further research on the safety of transvaginal mesh repair of anterior or posterior vaginal wall prolapse should include details of patient selection, long-term outcomes including complications, type of mesh used and method of fixation, and quality of life.

Recommendation ID IPG599/1 Question Further research on the safety of transvaginal mesh repair of anterior or posterior vaginal wall prolapse should

Research recommendation Published October 2018

Treatment for people with an IOP of 22 or 23 mmHg:- What is the clinical and cost effectiveness of treating an intraocular pressure (IOP) of 22 or 23 mmHg in people with normal optic discs and visual fields?

Recommendation ID NG81/2 Question Treatment for people with an IOP of 22 or 23 mmHg:- What is the clinical and cost effectiveness of treating

Research recommendation Published October 2018

Optical coherence tomography for glaucoma:- What is the effectiveness and cost effectiveness of optical coherence tomography (OCT) for diagnosing and monitoring glaucoma?

Recommendation ID NG81/4 Question Optical coherence tomography for glaucoma:- What is the effectiveness and cost effectiveness of optical

Research recommendation Published October 2018

Monitoring adherence to treatment:- What is the clinical and cost effectiveness of using electronic alert systems designed to monitor and improve adherence with regular inhaled maintenance therapy in people with asthma?

Recommendation ID NG80/3 Question Monitoring adherence to treatment:- What is the clinical and cost effectiveness of using electronic alert

Research recommendation Published October 2018

Improving adherence to asthma medication:- What are the most clinically and cost-effective strategies to improve medicines adherence in adults, young people and children with asthma who are non-adherent to prescribed medicines?

Recommendation ID NG80/10 Question Improving adherence to asthma medication:- What are the most clinically and cost-effective strategies

Research recommendation Published October 2018

Further research is recommended to assess the diagnostic accuracy of the tests included in this assessment when used in combination; for example sequentially.

Recommendation ID DG31/3 Question Further research is recommended to assess the diagnostic accuracy of the tests included in this assessment

Research recommendation Published October 2018

Further research is recommended to assess:- inter-observer reproducibility of tests involving ultrasound scans (the ADNEX model and Simple Rules)- changes in clinical management based on test results from the ADNEX model, Overa (MIA2G), ROMA and Simple Rules.

Recommendation ID DG31/2 Question Further research is recommended to assess:- inter-observer reproducibility of tests involving ultrasound

Research recommendation Published October 2018

Decreasing pharmacological treatment:- In adults, young people and children with well-controlled asthma, what are the objective measurements and prognostic factors that indicate that a decrease in regular maintenance treatment is appropriate?

Recommendation ID NG80/9 Question Decreasing pharmacological treatment:- In adults, young people and children with well-controlled asthma

Research recommendation Published October 2018

Diagnosing asthma in adults (aged 17 and over):- What is the clinical and cost effectiveness of using an indirect bronchial challenge test with mannitol to diagnose asthma in adults (aged 17 and over)?

Recommendation ID NG80/2 Question Diagnosing asthma in adults (aged 17 and over):- What is the clinical and cost effectiveness of using

Research recommendation Published October 2018