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Effectiveness of home visiting following child abuse or neglect:- Are home visiting interventions effective and cost effective in improving parenting and preventingrecurrence of child abuse and neglect in families in which abuse or neglect is occurring or has occurred?

Recommendation ID NG76/12 Question Effectiveness of home visiting following child abuse or neglect:- Are home visiting interventions effective

Research recommendation Published October 2018

Early help home visiting:- What are the components of effective home visiting programmes for preventing child abuse and neglect in families of children and young people at risk of child abuse and neglect in the UK?

Recommendation ID NG76/4 Question Early help home visiting:- What are the components of effective home visiting programmes for preventing

Research recommendation Published October 2018

Team composition for home-based intermediate care:- How effective and cost effective are different approaches, in terms of team structure and composition, to providing home-based intermediate care for adults?

Recommendation ID NG74/2 Question Team composition for home-based intermediate care:- How effective and cost effective are different approaches

Research recommendation Published October 2018

Support needs of parents:- What are the experiences and concerns of parents of children with faltering growth?

Recommendation ID NG75/5 Question Support needs of parents:- What are the experiences and concerns of parents of children with faltering

Research recommendation Published October 2018

Support for black and minority ethnic groups:- How effective and cost effective are different approaches to supporting people from black and minority ethnic groups using intermediate care?

Recommendation ID NG74/8 Question Support for black and minority ethnic groups:- How effective and cost effective are different approaches

Research recommendation Published October 2018

Reablement:- How effective and cost effective are repeated periods of reablement, and reablement that lasts longer than 6 weeks?

Recommendation ID NG74/5 Question Reablement:- How effective and cost effective are repeated periods of reablement, and reablement that

Research recommendation Published October 2018

Pain management programmes:- Are pain management programmes a clinically and cost-effective intervention for women with endometriosis?

Recommendation ID NG73/1 Question Pain management programmes:- Are pain management programmes a clinically and cost-effective intervention

Research recommendation Published October 2018

Optimal time between referral and starting intermediate care:- What is the optimal time between referral to and starting intermediate care in terms of effectiveness and cost effectiveness and in terms of people's experiences?

Recommendation ID NG74/1 Question Optimal time between referral and starting intermediate care:- What is the optimal time between referral

Research recommendation Published October 2018

Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise) effective, compared with no specialist lifestyle interventions, for women with endometriosis?

Recommendation ID NG73/3 Question Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise)

Research recommendation Published October 2018

Laparoscopic treatment of peritoneal endometriosis (excision or ablation):- Is laparoscopic treatment (excision or ablation) of peritoneal disease in isolation effective formanaging endometriosis-related pain?

Recommendation ID NG73/2 Question Laparoscopic treatment of peritoneal endometriosis (excision or ablation):- Is laparoscopic treatment

Research recommendation Published October 2018

Information and support:- What information and support interventions are effective to help women with endometriosis deal with their symptoms and improve their quality of lives?

Recommendation ID NG73/4 Question Information and support:- What information and support interventions are effective to help women with

Research recommendation Published October 2018

High energy liquid feed supplements:- Do high energy liquid feed supplements improve growth in children with faltering growth?

Recommendation ID NG75/1 Question High energy liquid feed supplements:- Do high energy liquid feed supplements improve growth in children

Research recommendation Published October 2018

Further research should give details of patient selection, patient-reported outcomes and long-term effects including survival and quality of life. NICE may update the guidance on publication of further evidence.

Recommendation ID IPG594/1 Question Further research should give details of patient selection, patient-reported outcomes and long-term effects

Research recommendation Published October 2018

Frequency of monitoring:- How frequently should children be measured to identify faltering growth?

Recommendation ID NG75/4 Question Frequency of monitoring:- How frequently should children be measured to identify faltering growth?

Research recommendation Published October 2018

Feeding interventions for the management of neonatal weight loss:- What is the effectiveness of feeding interventions compared with usual care/advice for breastfedneonates (up to 28 days old) with weight loss of greater than 10%?

Recommendation ID NG75/2 Question Feeding interventions for the management of neonatal weight loss:- What is the effectiveness of feeding

Research recommendation Published October 2018

Duration and intensity of home-based intermediate care:- How effective and cost effective are different approaches, in terms of duration and intensity, to providing home-based intermediate care for adults?

Recommendation ID NG74/7 Question Duration and intensity of home-based intermediate care:- How effective and cost effective are different

Research recommendation Published October 2018

Dementia care:- How effective and cost effective is intermediate care including reablement for supporting people living with dementia?

Recommendation ID NG74/4 Question Dementia care:- How effective and cost effective is intermediate care including reablement for supporting

Research recommendation Published October 2018

Crisis response:- What are the barriers and facilitators to providing an effective and cost effective crisis response service, with particular reference to different models for structuring delivery of this service?

Recommendation ID NG74/3 Question Crisis response:- What are the barriers and facilitators to providing an effective and cost effective

Research recommendation Published October 2018

Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual care/advice for children with faltering growth?

Recommendation ID NG75/3 Question Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual

Research recommendation Published October 2018

A single point of access for intermediate care:- How effective and cost effective is introducing a single point of access to intermediate care?

Recommendation ID NG74/6 Question A single point of access for intermediate care:- How effective and cost effective is introducing a single

Research recommendation Published October 2018

Diagnosing asthma in adults (aged 17 and over):- What is the clinical and cost effectiveness of using an indirect bronchial challenge test with mannitol to diagnose asthma in adults (aged 17 and over)?

Recommendation ID NG80/2 Question Diagnosing asthma in adults (aged 17 and over):- What is the clinical and cost effectiveness of using

Research recommendation Published October 2018

An instrument to measure quality of life in people with glaucoma:- What instrument should be used to measure health related quality of life in people with glaucoma?

Recommendation ID NG81/3 Question An instrument to measure quality of life in people with glaucoma:- What instrument should be used to measure

Research recommendation Published October 2018

Relative effectiveness of interventions to support foster carers:- What is the relative effectiveness and cost effectiveness of the KEEP intervention for foster carersof abused or neglected children compared to other interventions?

Recommendation ID NG76/15 Question Relative effectiveness of interventions to support foster carers:- What is the relative effectiveness

Research recommendation Published October 2018

Quality of life in cataract surgery:- What vision-specific, quality-of-life measures best capture visual changes in a population with cataracts?

Recommendation ID NG77/2 Question Quality of life in cataract surgery:- What vision-specific, quality-of-life measures best capture visual

Research recommendation Published October 2018

Psychological assessment:- What is the most effective measure of psychological functioning to use as a test for thresholds of concern in people with cystic fibrosis?

Recommendation ID NG78/4 Question Psychological assessment:- What is the most effective measure of psychological functioning to use as a

Research recommendation Published October 2018

Peer support for children and young people who have been abused or neglected:- What peer support programmes are effective and cost effective in improving the wellbeing of children and young people who have been abused or neglected?

Recommendation ID NG76/16 Question Peer support for children and young people who have been abused or neglected:- What peer support programmes

Research recommendation Published October 2018

Mucoactive agents:- What is the most clinically and cost-effective dose of rhDNase (dornase alfa; recombinant human deoxyribonuclease) for people with cystic fibrosis?

Recommendation ID NG78/6 Question Mucoactive agents:- What is the most clinically and cost-effective dose of rhDNase (dornase alfa; recombinant

Research recommendation Published October 2018

Monitoring for cystic-fibrosis-related diabetes:- What is the most effective strategy to detect diabetes in people with cystic fibrosis?

Recommendation ID NG78/5 Question Monitoring for cystic-fibrosis-related diabetes:- What is the most effective strategy to detect diabetes

Research recommendation Published October 2018

Liver disease:- Should all children with meconium ileus receive ursodeoxycholic acid from diagnosis?

Recommendation ID NG78/1 Question Liver disease:- Should all children with meconium ileus receive ursodeoxycholic acid from diagnosis?

Research recommendation Published October 2018

Interventions with male foster carers and adoptive parents:- What interventions are effective and cost effective when working with male foster carers and adoptive parents who are caring for children and young people who have been abused in the past?

Recommendation ID NG76/11 Question Interventions with male foster carers and adoptive parents:- What interventions are effective and cost

Research recommendation Published October 2018

Interventions with fathers and male carers:- What interventions are effective and cost effective when working with fathers and male carers to improve their parenting in families where children are being, or have been, abused or neglected?

Recommendation ID NG76/10 Question Interventions with fathers and male carers:- What interventions are effective and cost effective when

Research recommendation Published October 2018

Interventions to prevent endophthalmitis:- What is the effectiveness of postoperative antibiotic drops to reduce rates of endophthalmitis after cataract surgery?

Recommendation ID NG77/5 Question Interventions to prevent endophthalmitis:- What is the effectiveness of postoperative antibiotic drops

Research recommendation Published October 2018

Interventions to manage cystoid macular oedema:- What is the most effective postoperative medical management for cystoid macular oedema?

Recommendation ID NG77/4 Question Interventions to manage cystoid macular oedema:- What is the most effective postoperative medical management

Research recommendation Published October 2018

Effective prevention of child abuse and neglect in the UK:- What interventions are effective and cost effective in the UK to prevent abuse and neglect of children and young people in families at risk of, or showing early signs of, abuse and neglect?

Recommendation ID NG76/5 Question Effective prevention of child abuse and neglect in the UK:- What interventions are effective and cost

Research recommendation Published October 2018

Effectiveness of web-based parenting programmes:- Are web-based parenting programmes effective and cost effective for improving parenting and preventing recurrence of child abuse and neglect in families where child abuse or neglect has occurred?

Recommendation ID NG76/14 Question Effectiveness of web-based parenting programmes:- Are web-based parenting programmes effective and cost

Research recommendation Published October 2018

NICE encourages further research into total artificial heart implantation as a bridge to transplantation for end-stage refractory biventricular heart failure, including well matched comparative studies. NICE may update the guidance on publication of further evidence.

Recommendation ID IPG602/1 Question NICE encourages further research into total artificial heart implantation as a bridge to transplantation

Research recommendation Published October 2018

Further research on the safety of transvaginal mesh repair of anterior or posterior vaginal wall prolapse should include details of patient selection, long-term outcomes including complications, type of mesh used and method of fixation, and quality of life.

Recommendation ID IPG599/1 Question Further research on the safety of transvaginal mesh repair of anterior or posterior vaginal wall prolapse should

Research recommendation Published October 2018

Treatment for people with an IOP of 22 or 23 mmHg:- What is the clinical and cost effectiveness of treating an intraocular pressure (IOP) of 22 or 23 mmHg in people with normal optic discs and visual fields?

Recommendation ID NG81/2 Question Treatment for people with an IOP of 22 or 23 mmHg:- What is the clinical and cost effectiveness of treating

Research recommendation Published October 2018