Updating results

Training:- How effective and cost effective is gatekeeper training in preventing suicides?

Recommendation ID NG105/4 Question Training:- How effective and cost effective is gatekeeper training in preventing suicides? Any explanatory

Research recommendation Published December 2018

Non-clinical interventions:- How effective and cost effective are non-clinical interventions to reduce suicidal behaviours?

Recommendation ID NG105/1 Question Non-clinical interventions:- How effective and cost effective are non-clinical interventions to reduce

Research recommendation Published December 2018

Supporting people bereaved or affected by a suicide:- How effective and cost effective are interventions to support people in the community who are bereaved or affected by a suicide?

Recommendation ID NG105/2 Question Supporting people bereaved or affected by a suicide:- How effective and cost effective are interventions

Research recommendation Published December 2018

The impact of atrial fibrillation on the natriuretic peptide threshold for diagnosing heart failure:- What is the optimal NT-proBNP threshold for the diagnosis of heart failure in people with atrial fibrillation?

Recommendation ID NG106/3 Question The impact of atrial fibrillation on the natriuretic peptide threshold for diagnosing heart failure:- What

Research recommendation Published December 2018

Cardiac MRI versus other imaging techniques for diagnosing heart failure:- What is the optimal imaging technique for the diagnosis of heart failure?

Recommendation ID NG106/2 Question Cardiac MRI versus other imaging techniques for diagnosing heart failure:- What is the optimal imaging

Research recommendation Published December 2018

Speed of intravenous fluid resuscitation for people with acute pancreatitis:- What is the most clinically effective and cost-effective speed of administration of intravenous fluid for resuscitation in people with acute pancreatitis?

Recommendation ID NG104/2 Question Speed of intravenous fluid resuscitation for people with acute pancreatitis:- What is the most clinically

Research recommendation Published December 2018

Pain management: small duct disease:- What is the most clinically effective and cost-effective intervention for managing small duct disease (in the absence of pancreatic duct obstruction, inflammatory mass or pseudocyst) in people with chronic pancreatitis presenting with pain?

Recommendation ID NG104/4 Question Pain management: small duct disease:- What is the most clinically effective and cost-effective intervention

Research recommendation Published December 2018

Management of type 3c diabetes:- What is the most clinically effective and cost-effective insulin regimen to minimise hypo- and hyperglycaemia for type 3c diabetes secondary to pancreatitis?

Recommendation ID NG104/5 Question Management of type 3c diabetes:- What is the most clinically effective and cost-effective insulin regimen

Research recommendation Published December 2018

Galaxy UNYCO for temporary stabilisation of lower limb fractures (MIB166)

Advice on the use of Galaxy UNYCO (single-use, external fixation system) for temporary stabilisation of lower limb fractures to aid local decision-making

Medtech innovation briefing Published December 2018

Further research in superior rectal artery embolisation for haemorrhoids should report details of patient selection, and follow-up efficacy (including symptom relief), need for subsequent treatments, quality of life and safety outcomes for at least 1 year.

Recommendation ID IPG627/1 Question Further research in superior rectal artery embolisation for haemorrhoids should report details of patient

Research recommendation Published December 2018

Opt-out strategies for front-line health and social care staff:- Are opt-out strategies effective and cost effective at increasing uptake of flu vaccination among front-line health and social care staff?

Recommendation ID NG103/4 Question Opt-out strategies for front-line health and social care staff:- Are opt-out strategies effective and

Research recommendation Published December 2018

Cerebrotech Visor for detecting stroke (MIB165)

Advice on the use of Cerebrotech Visor for detecting stroke to aid local decision-making

Medtech innovation briefing Published December 2018

Community-based models of flu vaccination:- What models of community-based flu vaccination provision (for example, community pharmacies, community nursing and midwifery teams and outreach services) are effective and cost-effective for increasing uptake in eligible groups?

Recommendation ID NG103/5 Question Community-based models of flu vaccination:- What models of community-based flu vaccination provision

Research recommendation Published December 2018

Underserved groups:- What are the most effective and cost-effective ways of reaching underserved groups and removing barriers to access in order to increase their uptake of flu vaccination?

Recommendation ID NG103/2 Question Underserved groups:- What are the most effective and cost-effective ways of reaching underserved groups

Research recommendation Published December 2018

People in eligible groups:- What are the important messages and how should they be tailored and delivered to encourage and sustain flu vaccination uptake in eligible groups?

Recommendation ID NG103/1 Question People in eligible groups:- What are the important messages and how should they be tailored and delivered

Research recommendation Published December 2018

Addressing health inequalities:- What are the barriers to and facilitators for increasing access to community pharmacy services by underserved groups? How should health and wellbeing interventions be tailored to increase service uptake in underserved groups?

Recommendation ID NG102/3 Question Addressing health inequalities:- What are the barriers to and facilitators for increasing access to community

Research recommendation Published December 2018

Referral within a formal care pathway:- Is referral from a community pharmacy within a formal local care pathway framework more effective and cost effective than signposting alone in improving access to, and uptake of, services by underserved groups and the general population?

Recommendation ID NG102/1 Question Referral within a formal care pathway:- Is referral from a community pharmacy within a formal local care

Research recommendation Published December 2018

Carers:- In what context is it cost effective to increase uptake of flu vaccination among carers?

Recommendation ID NG103/3 Question Carers:- In what context is it cost effective to increase uptake of flu vaccination among carers?

Research recommendation Published December 2018

NICE encourages further research into low-intensity pulsed ultrasound to promote healing of delayed-union and non-union fractures. Further research should include details of patient selection, fracture site, and risk factors and comorbidities that delay fracture healing.

Recommendation ID IPG623/1 Question NICE encourages further research into low-intensity pulsed ultrasound to promote healing of delayed-union

Research recommendation Published December 2018

Neoadjuvant endocrine therapy in postmenopausal women:- Is there a benefit for neoadjuvant endocrine therapy in postmenopausal women with early breast cancer?

Recommendation ID NG101/5 Question Neoadjuvant endocrine therapy in postmenopausal women:- Is there a benefit for neoadjuvant endocrine

Research recommendation Published December 2018

Neoadjuvant endocrine therapy in premenopausal women:- Is neoadjuvant endocrine therapy safe in premenopausal women with early breast cancer?

Recommendation ID NG101/4 Question Neoadjuvant endocrine therapy in premenopausal women:- Is neoadjuvant endocrine therapy safe in premenopausal

Research recommendation Published December 2018

Managing meningioma: immediate versus deferred radiotherapy for incompletely excised grade I meningioma:- Is immediate or deferred radiotherapy better for incompletely excised grade I meningioma?

Recommendation ID NG99/5 Question Managing meningioma: immediate versus deferred radiotherapy for incompletely excised grade I meningioma:-

Research recommendation Published December 2018

Further research in low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk of non-healing should include details of patient selection, fracture site, and risk factors and comorbidities that delay fracture healing.

Recommendation ID IPG622/1 Question Further research in low-intensity pulsed ultrasound to promote healing of fresh fractures at high risk

Research recommendation Published December 2018

Managing glioma: management of IDH wildtype grade II glioma:- Does the addition of concurrent and adjuvant temozolomide to radiotherapy improve overall survival in patients with IDH wildtype grade II glioma?

Recommendation ID NG99/1 Question Managing glioma: management of IDH wildtype grade II glioma:- Does the addition of concurrent and adjuvant

Research recommendation Published December 2018

Managing glioma: early referral to palliative care for glioblastoma:- Does early referral to palliative care improve outcomes for people with glioblastomas in comparison with standard oncology care?

Recommendation ID NG99/3 Question Managing glioma: early referral to palliative care for glioblastoma:- Does early referral to palliative

Research recommendation Published December 2018

Managing glioma: early detection of recurrence after treatment:- Does early detection of recurrence after treatment improve overall survival/outcomes inmolecularly stratified glioma?

Recommendation ID NG99/4 Question Managing glioma: early detection of recurrence after treatment:- Does early detection of recurrence after

Research recommendation Published December 2018

Managing glioma: supportive care clinics for low-grade glioma:- Does a dedicated supportive care clinic in addition to standard care improve outcomes for people with low-grade gliomas?

Recommendation ID NG99/2 Question Managing glioma: supportive care clinics for low-grade glioma:- Does a dedicated supportive care clinic

Research recommendation Published December 2018

Adjuvant bisphosphonate therapy:- Which groups of people with early and locally advanced breast cancer would benefit from the use of adjuvant bisphosphonates?

Recommendation ID NG101/2 Question Adjuvant bisphosphonate therapy:- Which groups of people with early and locally advanced breast cancer

Research recommendation Published December 2018

Surgery to the breast:- What is the optimum tumour-free margin width after breast-conserving surgery for women with ductal carcinoma in situ (DCIS) and invasive breast cancer?

Recommendation ID NG101/1 Question Surgery to the breast:- What is the optimum tumour-free margin width after breast-conserving surgery

Research recommendation Published December 2018

Ultrasound in monitoring:- What is the clinical and cost effectiveness of using ultrasound to monitor disease in adults with RA when clinical examination is inconclusive or inconsistent with other signs of disease activity?

Recommendation ID NG100/3 Question Ultrasound in monitoring:- What is the clinical and cost effectiveness of using ultrasound to monitor

Research recommendation Published December 2018

Ultrasound in diagnosis:- What is the clinical and cost effectiveness of using ultrasound in addition to clinical assessment when there is uncertainty about the diagnosis in adults with suspected RA?

Recommendation ID NG100/4 Question Ultrasound in diagnosis:- What is the clinical and cost effectiveness of using ultrasound in addition

Research recommendation Published December 2018

Subcutaneous methotrexate:- What is the clinical and cost effectiveness of subcutaneous methotrexate compared with oral methotrexate for adults with early onset RA starting a new DMARD?

Recommendation ID NG100/6 Question Subcutaneous methotrexate:- What is the clinical and cost effectiveness of subcutaneous methotrexate

Research recommendation Published December 2018

Analgesics:- What is the clinical and cost effectiveness of analgesic drugs other than non-steroidal antiinflammatory drugs (NSAIDs) in adults with rheumatoid arthritis (RA) whose pain or stiffness control is not adequate?

Recommendation ID NG100/1 Question Analgesics:- What is the clinical and cost effectiveness of analgesic drugs other than non-steroidal

Research recommendation Published December 2018

Breast reconstruction:- What are the long-term outcomes for breast reconstruction in women having radiotherapy to the chest wall?

Recommendation ID NG101/3 Question Breast reconstruction:- What are the long-term outcomes for breast reconstruction in women having radiotherapy

Research recommendation Published December 2018

Neoadjuvant treatment:- What are the indications for postmastectomy radiotherapy after neoadjuvant chemotherapy?

Recommendation ID NG101/6 Question Neoadjuvant treatment:- What are the indications for postmastectomy radiotherapy after neoadjuvant chemotherapy

Research recommendation Published December 2018

Hearing loss prevalence in people who under-present for hearing loss:- What is the prevalence of hearing loss among populations who under-present for possible hearingloss?

Recommendation ID NG98/4 Question Hearing loss prevalence in people who under-present for hearing loss:- What is the prevalence of hearing

Research recommendation Published December 2018

Idiopathic sudden sensorineural hearing loss:- What is the most effective route of administration of steroids as a first-line treatment for idiopathic sudden sensorineural hearing loss?

Recommendation ID NG98/1 Question Idiopathic sudden sensorineural hearing loss:- What is the most effective route of administration of steroids

Research recommendation Published December 2018

Case management:- What is the effectiveness and cost effectiveness of high-intensity case management compared with usual care on quality of life (for the person living with dementia and for their carers) and the timing of entry to long-term care?

Recommendation ID NG97/1 Question Case management:- What is the effectiveness and cost effectiveness of high-intensity case management compared

Research recommendation Published December 2018

Staff training:- What is the cost effectiveness of using a dementia-specific addition to the Care Certificate for community staff, including dementia-specific elements on managing anxiety, communication, nutritional status and personal care?

Recommendation ID NG97/2 Question Staff training:- What is the cost effectiveness of using a dementia-specific addition to the Care Certificate

Research recommendation Published December 2018

Monitoring and follow-up for adults with hearing loss:- What is the clinical and cost effectiveness of monitoring and follow-up for adults with hearing loss post-intervention compared with usual care?

Recommendation ID NG98/5 Question Monitoring and follow-up for adults with hearing loss:- What is the clinical and cost effectiveness of

Research recommendation Published December 2018

Earwax:- What is the clinical and cost effectiveness of microsuction compared with irrigation to remove earwax?

Recommendation ID NG98/2 Question Earwax:- What is the clinical and cost effectiveness of microsuction compared with irrigation to remove earwax

Research recommendation Published December 2018