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Interstitial cystitis: dimethyl sulfoxide bladder instillation (ESUOM26)

Summary of the evidence on dimethyl sulfoxide bladder instillation for treating interstitial cystitis to inform local NHS planning and decision-making

Evidence summary Published February 2014

Migraine prophylaxis: flunarizine (ESUOM33)

Summary of the evidence on flunarizine for treating migraine prophylaxis to inform local NHS planning and decision-making

Evidence summary Published September 2014

Autoimmune haemolytic anaemia: rituximab (ESUOM39)

Summary of the evidence on rituximab for treating autoimmune haemolytic anaemia (AIHA) to inform local NHS planning and decision-making

Evidence summary Published February 2015

Interstitial cystitis: oral pentosan polysulfate sodium (ESUOM43)

Summary of the evidence on oral pentosan polysulfate sodium for treating interstitial cystitis to inform local NHS planning and decision-making

Evidence summary Published April 2015

Hypersexuality: fluoxetine (ESUOM46)

Summary of the evidence on fluoxetine for treating hypersexuality to inform local NHS planning and decision-making

Evidence summary Published July 2015

Xpert Carba-R to identify people carrying carbapenemase-producing organisms (MIB52)

Advice on the Xpert Carba-R test for identifying organisms that have carbapenemase genes to aid local decision-making

Medtech innovation briefing Published February 2016

TearLab osmolarity system for diagnosing dry eye disease (MIB47)

Advice on the use of the TearLab osmolarity system for diagnosing dry eye disease to aid local decision-making

Medtech innovation briefing Published December 2015

Icare rebound tonometer to measure intraocular pressure (MIB57)

Advice on the use of the Icare rebound tonometer to measure intraocular pressure and assess the risk of developing glaucoma to aid local decision-making

Medtech innovation briefing Published March 2016

Prolaris gene expression assay for assessing long-term risk of prostate cancer progression (MIB65)

Advice on the use of the Prolaris gene expression assay for assessing the risk of prostate cancer progression to aid local decision-making

Medtech innovation briefing Published May 2016

NaviCam for diagnosing gastrointestinal tract conditions (MIB104)

Advice on the use of NaviCam for diagnosing gastrointestinal (GI) tract and small bowel conditions to aid local decision-making

Medtech innovation briefing Published May 2017

The SENSIMED Triggerfish contact lens sensor for continuous 24-hour recording of ocular dimensional changes in people with or at risk of developing glaucoma (MIB14)

Advice on the use of the SENSIMED Triggerfish contact lens sensor for use in people with or at risk of developing glaucoma

Medtech innovation briefing Published November 2014

The OSCAR 3 ultrasonic arthroplasty revision instrument for removing bone cement during prosthetic joint revision (MIB13)

Advice on the use of the OSCAR 3 ultrasonic arthroplasty revision instrument for removing bone cement during prosthetic joint revision..

Medtech innovation briefing Published November 2014

The PressureWire fractional flow reserve measurement system for coronary artery disease (MIB2)

Advice on the use of the PressureWire fractional flow reserve measurement system for coronary artery disease to aid local decision-making

Medtech innovation briefing Published February 2014

TheraSphere for treating operable and inoperable hepatocellular carcinoma (MIB62)

Advice on the use of TheraSphere for treating operable and inoperable hepatocellular carcinoma (liver cancer) to aid local decision-making

Medtech innovation briefing Published March 2016

CareLink network service for remote monitoring of people with cardiac devices (MIB64)

Advice on the use of the CareLink network service for monitoring cardiac devices to aid local decision-making

Medtech innovation briefing Published May 2016

Mobi-C for cervical disc replacement (MIB70)

Advice on the use of Mobi-C for cervical disc replacement to aid local decision-making

Medtech innovation briefing Published June 2016

Polycystic ovary syndrome: metformin in women not planning pregnancy (ESUOM6)

Summary of the evidence on metformin for polycystic ovary syndrome (PCOS) in women not planning pregnancy to inform local NHS planning and decision-making

Evidence summary Published February 2013

Attention deficit hyperactivity disorder in children and young people: clonidine (ESUOM8)

Summary of the evidences on clonidine for attention deficit hyperactivity disorder (ADHD) in children and young people..

Evidence summary Published April 2013

Renin-angiotensin system drugs: dual therapy (KTT2)

KTT2 Renin-angiotensin system drugs: dual therapy Options for local implementation Dual

Key therapeutic topic Published January 2015 Last updated February 2016

The Versajet II hydrosurgery system for surgical debridement of acute and chronic wounds and burns (MIB1)

Advice on the use of the Versajet II hydrosurgery system for surgical debridement of acute and chronic wounds and burns to aid local decision-making

Medtech innovation briefing Published February 2014

Inflammatory lesions of papulopustular rosacea: ivermectin 10 mg/g cream (ESNM68)

Summary of the evidence on ivermectin 10 mg/g cream for treating papulopustular rosacea to inform local NHS planning and decision-making

Evidence summary Published January 2016

Type 1 diabetes mellitus in adults: high-strength insulin glargine 300 units/ml (Toujeo) (ESNM62)

Summary of the evidence on high-strength insulin glargine 300 units/ml (Toujeo) for type 1 diabetes mellitus to inform local NHS planning and decision-making

Evidence summary Published October 2015

Facial erythema of rosacea: brimonidine tartrate gel (ESNM43)

Summary of the evidence on brimonidine tartrate gel for treating facial erythema of rosacea to inform local NHS planning and decision-making

Evidence summary Published July 2014

Systemic juvenile idiopathic arthritis: canakinumab (ESNM36)

Summary of the evidence on canakinumab for treating systemic juvenile idiopathic arthritis (JIA) to inform local NHS planning and decision-making

Evidence summary Published March 2014

Type 2 diabetes: insulin degludec/liraglutide (Xultophy) (ESNM60)

Summary of the evidence on insulin degludec/liraglutide (Xultophy) for treating type 2 diabetes to inform local NHS planning and decision-making

Evidence summary Published July 2015

Minimal change disease and focal segmental glomerulosclerosis in adults: rituximab (ES1)

Summary of the evidence on rituximab for minimal change disease and focal segmental glomerulosclerosis to inform local NHS planning and decision-making

Evidence summary Published November 2016

Type 2 diabetes: alogliptin (ESNM20)

Summary of the evidence on alogliptin (a dipeptidyl peptidase-4 [DPP-4] inhibitor) for type 2 diabetes to inform local NHS planning and decision-making

Evidence summary Published May 2013 Last updated October 2014

Attention deficit hyperactivity disorder in children and young people: lisdexamfetamine dimesylate (ESNM19)

Summary of the evidence on lisdexamfetamine dimesylate for attention defecit hyperactivity disorder (ADHD) in children and young people..

Evidence summary Published May 2013

Lower urinary tract symptoms secondary to benign prostatic hyperplasia: tadalafil (ESNM18)

Summary of the evidence on tadalafil for lower urinary tract symptoms secondary to benign prostate hyperplasia..

Evidence summary Published May 2013 Last updated October 2013

Actinic keratosis: ingenol mebutate gel (ESNM14)

Summary of the evidence on ingenol mebutate gel for actinic keratosis (solar keratosis) to inform local NHS planning and decision-making

Evidence summary Published March 2013

Acute diarrhoea in children: racecadotril as an adjunct to oral rehydration (ESNM12)

Summary of the evidence on racecadotril with oral rehydration for treating acute diarrhoea in children to inform local NHS planning and decision-making

Evidence summary Published March 2013

Shiley Endotracheal Tube with TaperGuard Cuff for intensive care patients at risk of ventilator‑associated pneumonia (MIB22)

Advice on the use of Shiley Endotracheal Tube with TaperGuard Cuff for patients at risk of ventilator-associated pneumonia to aid local decision-making

Medtech innovation briefing Published March 2015

The PediGuard for placing pedicle screws in spinal surgery (MIB26)

Advice on the use of the PediGuard for placing pedicle screws in spinal surgery to aid local decision-making

Medtech innovation briefing Published March 2015

Xpert GBS test for the intrapartum detection of group B streptococcus (MIB28)

Advice on the use of the Xpert GBS test for the intrapartum detection of group B streptococcus (GBS) colonisation in pregnant women...

Medtech innovation briefing Published April 2015

Acute diarrhoea in adults: racecadotril (ESNM11)

Summary of the evidence on racecadotril for treating acute diarrhoea in adults to inform local NHS planning and decision-making

Evidence summary Published March 2013

Combined oral contraception: nomegestrol/estradiol (Zoely) (ESNM28)

Summary of the evidence on nomegestrol/estradiol (Zoely) for use as combined oral contraception to inform local NHS planning and decision-making

Evidence summary Published December 2013

Asthma: beclometasone/formoterol (Fostair) for maintenance and reliever treatment (ESNM22)

Summary of the evidence on beclometasone/formoterol (Fostair) for treating asthma to inform local NHS planning and decision-making

Evidence summary Published June 2013

Irritable bowel syndrome with constipation in adults: linaclotide (ESNM16)

Summary of the evidence on linaclotide for irritable bowel syndrome (IBS) with constipation in adults to inform local NHS planning and decision-making

Evidence summary Published April 2013

Pulmonary sarcoidosis: infliximab (ES2)

Summary of the evidence on infliximab for treating pulmonary sarcoidosis to inform local NHS planning and decision-making

Evidence summary Published December 2016

Hospital-acquired pneumonia caused by methicillin-resistant Staphylococcus aureus: telavancin (ESNM44)

Summary of the evidence on telavancin (Vibativ) for hospital-acquired pneumonia caused by MRSA to inform local NHS planning and decision-making

Evidence summary Published July 2014

Asthma: fluticasone furoate/vilanterol (Relvar Ellipta) combination inhaler (ESNM34)

Summary of the evidence on the fluticasone furoate/vilanterol (Relvar Ellipta) combination inhaler for asthma to inform local NHS planning and decision-making

Evidence summary Published March 2014

Oestrogen deficiency symptoms in postmenopausal women: conjugated oestrogens and bazedoxifene acetate (ES3)

Summary of the evidence on conjugated oestrogens and bazedoxifene acetate for oestrogen deficiency symptoms to inform local NHS planning and decision-making

Evidence summary Published December 2016

Chronic obstructive pulmonary disease: fluticasone furoate plus vilanterol (ESNM21)

Summary of the evidence on fluticasone furoate plus vilanterol for treating chronic obstructive pulmonary disease (COPD)..

Evidence summary Published June 2013

Partial-onset seizures in epilepsy: perampanel as adjunctive treatment (ESNM7)

Summary of the evidence on perampanel for partial-onset seizures in epilepsy (in people aged 12 and over) to inform local NHS planning and decision-making

Evidence summary Published December 2012

Gastroparesis in adults: oral erythromycin (ESUOM13)

Summary of the evidence on oral erythromycin for gastroparesis (delayed stomach emptying) in adults to inform local NHS planning and decision-making

Evidence summary Published June 2013

Hyperhidrosis: oral glycopyrronium bromide (ESUOM16)

Summary of the evidence on oral glycopyrronium bromide for treating hyperhidrosis (excessive sweating) to inform local NHS planning and decision-making

Evidence summary Published July 2013

Mitochondrial disorders in children: Co-enzyme Q10 (ES11)

Summary of the evidence on co-enzyme Q10 for mitochondrial disorders in children to inform local NHS planning and decision-making

Evidence summary Published March 2017

Hyperhidrosis: oxybutynin (ES10)

Summary of the evidence on oxybutynin for treating hyperhidrosis (excessive sweating) to inform local NHS planning and decision-making

Evidence summary Published March 2017

Type 2 diabetes: lixisenatide (ESNM26)

Summary of the evidence on lixisenatide (glucagon-like peptide-1 [GLP-1] mimetic) for treating type 2 diabetes to inform local NHS planning and decision-making

Evidence summary Published September 2013

Induction of labour: misoprostol vaginal delivery system (ESNM38)

Summary of the evidence on the misoprostol vaginal delivery system for induction of labour to inform local NHS planning and decision-making

Evidence summary Published March 2014 Last updated November 2014