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Postural hypotension in adults: fludrocortisone (ESUOM20)

Summary of the evidence on fludrocortisone for treating postural hypotension in adults to inform local NHS planning and decision-making

Evidence summary Published October 2013

Promoting tolerance of enteral feeds in children and young people: domperidone (ESUOM18)

Summary of the evidence on domperidone to promote tolerance of enteral feeds in children and young people..

Evidence summary Published July 2013 Last updated September 2014

Transient ischaemic attack: clopidogrel (ESUOM23)

Summary of the evidence on clopidogrel for treating transient ischaemic attack (TIA) to inform local NHS planning and decision-making

Evidence summary Published December 2013

Bile acid malabsorption: colesevelam (ESUOM22)

Summary of the evidence on colesevelam for treating bile acid malabsorption (BAM) to inform local NHS planning and decision-making

Evidence summary Published October 2013

Shared decision making (KTT23)

KTT23 Shared decision making Key points In the context of medicines optimisation, shared

Key therapeutic topic Published March 2019 Last updated September 2019

InterDry for intertrigo (MIB192)

Advice on the use of InterDry for intertrigo (inflammatory skin rash) to aid local decision making

Medtech innovation briefing Published September 2019

Ovarian cancer (advanced): bevacizumab 7.5 mg/kg in combination with paclitaxel and carboplatin for first-line treatment (ESUOM21)

Summary of the evidence on bevacizumab 7.5 mg/kg with paclitaxel and carboplatin for the first-line treatment of advanced ovarian cancer..

Evidence summary Published October 2013

Sleep disorders in children and young people with attention deficit hyperactivity disorder: melatonin (ESUOM2)

Summary of the evidence on melatonin for sleep disorders in children and young people with attention deficit hyperactivity disorder (ADHD)..

Evidence summary Published January 2013

UroShield for preventing catheter-associated urinary tract infections (MIB191)

Advice on the use of UroShield for preventing catheter-associated urinary tract infections (CAUTI) to aid local decision making

Medtech innovation briefing Published September 2019

SuperNO2VA for the relief of upper airway obstruction in people with obstructive sleep apnoea (MIB190)

Advice on the use of SuperNO2VA for the relief of upper airway obstruction in people with obstructive sleep apnoea to aid local decision making

Medtech innovation briefing Published September 2019

OxyMask for delivering oxygen therapy (MIB160)

Advice on the use of OxyMask for delivering oxygen therapy to aid local decision-making

Medtech innovation briefing Published September 2018

Suicide prevention: optimising medicines and reducing access to medicines as a means of suicide (KTT24)

KTT24 Suicide prevention: optimising medicines and reducing access to medicines as a means of suicide Key points

Key therapeutic topic Published March 2019 Last updated September 2019

Alpha-Stim AID for anxiety (MIB193)

Advice on the use of Alpha-Stim AID for anxiety to aid local decision making

Medtech innovation briefing Published September 2019

Psychotropic medicines in people with learning disabilities whose behaviour challenges (KTT19)

KTT19 Psychotropic medicines in people with learning disabilities whose behaviour challenges Key points

Key therapeutic topic Published January 2017 Last updated September 2019

Safer insulin prescribing (KTT20)

KTT20 Safer insulin prescribing Key points Several new insulin products have been launched

Key therapeutic topic Published January 2017 Last updated September 2019

Type 2 diabetes mellitus: medicines optimisation priorities (KTT12)

KTT12 Type 2 diabetes mellitus: medicines optimisation priorities Key points The NICE

Key therapeutic topic Published January 2015 Last updated September 2019

Multimorbidity and polypharmacy (KTT18)

KTT18 Multimorbidity and polypharmacy Key points Multimorbidity is associated with

Key therapeutic topic Published January 2017 Last updated September 2019

Asthma: medicines safety priorities (KTT5)

KTT5 Asthma: medicines safety priorities Key points Inhaled corticosteroids (ICS) are

Key therapeutic topic Published January 2015 Last updated September 2019

Antimicrobial stewardship: prescribing antibiotics (KTT9)

KTT9 Antimicrobial stewardship: prescribing antibiotics Key points Antimicrobial resistance

Key therapeutic topic Published January 2015 Last updated September 2019

Needle-free arterial non-injectable connector (MIB85)

Advice on the use of needle-free arterial non-injectable connector through which blood samples can be collected to aid local decision-making

Medtech innovation briefing Published October 2016

Alere Afinion CRP for C-reactive protein testing in primary care (MIB81)

Advice on the use of the Alere Afinion CRP for C-reactive protein testing in primary care to aid local decision-making

Medtech innovation briefing Published September 2016

QuikRead go for C-reactive protein testing in primary care (MIB78)

Advice on the use of QuickRead go for C-reactive protein (CRP) testing in primary care to aid local decision-making

Medtech innovation briefing Published September 2016

Anticoagulants, including direct-acting oral anticoagulants (DOACs) (KTT16)

KTT16 Anticoagulants, including direct-acting oral anticoagulants (DOACs) Key points

Key therapeutic topic Published February 2016 Last updated September 2019

Lipid-modifying drugs (KTT3)

KTT3 Lipid-modifying drugs Key points The NICE guideline on cardiovascular disease:

Key therapeutic topic Published January 2015 Last updated September 2019

Antipsychotics in people living with dementia (KTT7)

KTT7 Antipsychotics in people living with dementia Key points The risks and limited

Key therapeutic topic Published January 2015 Last updated September 2019

Wound care products (KTT14)

KTT14 Wound care products Key points A large number of wound dressings are available

Key therapeutic topic Published January 2015 Last updated September 2019

Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI (KTT17)

KTT17 Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI Key points

Key therapeutic topic Published February 2016 Last updated September 2019

Hypnotics (KTT6)

KTT6 Hypnotics Key points The risks associated with hypnotics (including melatonin)

Key therapeutic topic Published January 2015 Last updated September 2019

Medicines optimisation in chronic pain (KTT21)

KTT21 Medicines optimisation in chronic pain Key points Controlling chronic pain can

Key therapeutic topic Published January 2017 Last updated September 2019

Fungitell for antifungal treatment stratification (MIB118)

Advice on the use of the Fungitell assay for detecting fungal infections (pathogens, fungus, fungi) in guiding antifungal treatment to aid local decision-making

Medtech innovation briefing Published August 2017

Biopatch for venous or arterial catheter sites (MIB117)

Advice on the use of Biopatch hydrophilic foam dressing with chlorhexidine gluconate (CHG) for venous or arterial catheter sites to aid local decision-making

Medtech innovation briefing Published August 2017

Plasma EGFR mutation tests for adults with locally advanced or metastatic non-small-cell lung cancer (MIB137)

Advice on the use of plasma EGFR mutation tests for adults with locally advanced or metastatic non-small-cell lung cancer (NSCLC) to aid local decision-making

Medtech innovation briefing Published January 2018

Health app: GDm-Health for people with gestational diabetes (MIB131)

Advice on the GDm-Health app to remotely monitor blood glucose in people with gestational diabetes (diabetes in pregnancy) to aid local decision-making

Medtech innovation briefing Published November 2017

Chemotherapy dose standardisation (KTT22)

KTT22 Chemotherapy dose standardisation Key points Chemotherapy dose standardisation

Key therapeutic topic Published February 2018 Last updated September 2019

Long-acting reversible contraception: subcutaneous depot medroxyprogesterone acetate (DMPA‑SC) (ESNM31)

Summary of the evidence on subcutaneous depot medroxyprogesterone acetate (DMPA-SC) for long-acting reversible contraception..

Evidence summary Published January 2014

The OraQuick HCV point‑of‑care test for rapid detection of hepatitis C virus antibodies (MIB24)

Advice on the use of the OraQuick HCV point-of-care test for rapid detection of hepatitis C virus antibodies to aid local decision-making

Medtech innovation briefing Published March 2015

S-Cath System for suprapubic catheterisation (MIB68)

Advice on the use of the S-Cath System for suprapubic catheterisation to aid local decision-making

Medtech innovation briefing Published June 2016

Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine assessment and monitoring of changes in pulmonary status in people with cystic fibrosis?

Recommendation ID NG78/3 Question Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine

Research recommendation Published November 2018

Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative vision- and health-related quality of life, and postoperative vision-related quality of life, health-related quality of life, and self-reported postoperative improvement?

Recommendation ID NG77/3 Question Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative

Research recommendation Published November 2018

Further research on high-intensity focused ultrasound for symptomatic breast fibroadenoma should include publication of patient-reported outcome measures and studies with long-term follow-up.

Recommendation ID IPG592 Question Further research on high-intensity focused ultrasound for symptomatic breast fibroadenoma should include

Research recommendation Published November 2018

Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung function in infants and children with cystic fibrosis?

Recommendation ID NG78/2 Question Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung

Research recommendation Published November 2018

Duration and intensity of psychological treatment:- What is the effectiveness of treating eating disorders with psychological treatments of reduced duration and reduced intensity, compared with standard treatment?

Recommendation ID NG69/2 Question Duration and intensity of psychological treatment:- What is the effectiveness of treating eating disorders

Research recommendation Published October 2018

What measures would make up an effective, standardised approach to evaluation of condom distribution schemes?: How can we develop a standardised framework to evaluate condom schemes and what would be included in that evaluation?

Recommendation ID NG68/1 Question What measures would make up an effective, standardised approach to evaluation of condom distribution schemes

Research recommendation Published October 2018

What behaviour change techniques are most effective as part of a condom distribution scheme?:- What combinations of behaviour change techniques can be used to help condom schemes increase condom use among different high risk groups?

Recommendation ID NG68/1 Question What behaviour change techniques are most effective as part of a condom distribution scheme?:- What combinations

Research recommendation Published October 2018