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Renin-angiotensin system drugs: dual therapy (KTT2)

The key therapeutic topic renin-angiotensin system drugs: dual therapy has been retired from the 2017 update of medicines optimisation: key therapeutic topics. The version published in 2016 is available here for information but it has not been updated since February 2016. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated February 2016

Bindex for investigating suspected osteoporosis (MIB106)

Advice on the use of Bindex (portable pulse echo ultrasound device) for investigating suspected osteoporosis to aid local decision-making

Medtech innovation briefing Published May 2017

Permacol for treating anal fistulae (MIB105)

Advice on the use of Permacol for treating anal fistulae (fistula) to aid local decision-making

Medtech innovation briefing Published May 2017

NaviCam for diagnosing gastrointestinal tract conditions (MIB104)

Advice on the use of NaviCam for diagnosing gastrointestinal (GI) tract and small bowel conditions to aid local decision-making

Medtech innovation briefing Published May 2017

Hemosep for cell salvage (MIB103)

MIB103 No intro Summary The technology described in this briefing is Hemosep. It is used for cell salvage and

Medtech innovation briefing Published May 2017

VAAFT for treating anal fistulae (MIB102)

Advice on the use of VAAFT for treating anal fistulae to aid local decision-making

Medtech innovation briefing Published April 2017

Zio Service for detecting cardiac arrhythmias (MIB101)

Advice on the use of the Zio Service (a remote cardiac monitoring system) for detecting cardiac arrhythmias to aid local decision-making

Medtech innovation briefing Published March 2017

Mollii suit for spasticity (MIB100)

Advice on the use of Mollii suit (formerly Elektrodress; a therapeutic electrical stimulation jacket and trousers) for spasticity to aid local decision-making

Medtech innovation briefing Published March 2017

The Versajet II hydrosurgery system for surgical debridement of acute and chronic wounds and burns (MIB1)

Advice on the use of the Versajet II hydrosurgery system for surgical debridement of acute and chronic wounds and burns to aid local decision-making

Medtech innovation briefing Published February 2014

End-tidal Control software for use with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia (MIB10)

Advice on the use of End-tidal Control software with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia..

Medtech innovation briefing Published September 2014

First-choice antidepressant use in adults with depression or generalised anxiety disorder (KTT8)

The key therapeutic topic first-choice antidepressant use in adults with depression or generalised anxiety disorder has been retired from the 2017 update of medicines optimisation: key therapeutic topics. The version published in 2016 is available here for information but it has not been updated since February 2016. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015 Last updated February 2016

Laxatives (KTT1)

The key therapeutic topic laxatives has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015

Minocycline (KTT11)

The key therapeutic topic minocycline has been retired from the 2016 update of medicines optimisation: key therapeutic topics. The version published in 2015 is available here for information but it has not been updated since January 2015. Like all the other key therapeutic topics it is not formal NICE guidance.

Key therapeutic topic Published January 2015

Hyperhidrosis: oral glycopyrronium bromide (ESUOM16)

Summary of the evidence on oral glycopyrronium bromide for treating hyperhidrosis (excessive sweating) to inform local NHS planning and decision-making

Evidence summary Published July 2013

Hypersalivation: oral glycopyrronium bromide (ESUOM15)

Summary of the evidence on oral glycopyrronium bromide for treating hypersalivation (sialorrhoea) to inform local NHS planning and decision-making

Evidence summary Published July 2013

Chronic anal fissure: botulinum toxin type A injection (ESUOM14)

Summary of the evidence on botulinum toxin type A injection for treating chronic anal fissure to inform local NHS planning and decision-making

Evidence summary Published June 2013

Gastroparesis in adults: oral erythromycin (ESUOM13)

Summary of the evidence on oral erythromycin for gastroparesis (delayed stomach emptying) in adults to inform local NHS planning and decision-making

Evidence summary Published June 2013

Generalised anxiety disorder: quetiapine (ESUOM12)

Summary of the evidence on quetiapine monotherapy for treating generalised anxiety disorder (GAD) to inform local NHS planning and decision-making

Evidence summary Published May 2013

Xpert Carba-R to identify people carrying carbapenemase-producing organisms (MIB52)

Advice on the Xpert Carba-R test for identifying organisms that have carbapenemase genes to aid local decision-making

Medtech innovation briefing Published February 2016

MiniMed 640G system with SmartGuard for managing blood glucose levels in people with type 1 diabetes (MIB51)

Advice on the MiniMed 640G system with SmartGuard for managing blood glucose levels in type 1 diabetes to aid local decision-making

Medtech innovation briefing Published February 2016

BladderScan BVI 9400 3D portable ultrasound scanner for measuring bladder volume (MIB50)

Advice on the BladderScan BVI 9400 3D portable ultrasound scanner for measuring bladder volume to aid local decision-making

Medtech innovation briefing Published January 2016

Acoustic CR Neuromodulation for adults with chronic subjective tonal tinnitus (MIB5)

Advice on the use of the Acoustic CR Neuromodulation system for adults with chronic subjective tonal tinnitus to aid local decision-making

Medtech innovation briefing Published June 2014

EarlySense for heart and respiratory monitoring and predicting patient deterioration (MIB49)

Advice on the use of EarlySense for heart and respiratory monitoring and predicting patient deterioration to aid local decision-making

Medtech innovation briefing Published January 2016

CORTRAK 2 Enteral Access System for placing nasoenteral feeding tubes (MIB48)

Advice on the use of the CORTRAK 2 Enteral Access System (EAS) for the placement of nasoenteral feeding tube to aid local decision-making

Medtech innovation briefing Published January 2016 Last updated December 2016

TearLab osmolarity system for diagnosing dry eye disease (MIB47)

Advice on the use of the TearLab osmolarity system for diagnosing dry eye disease to aid local decision-making

Medtech innovation briefing Published December 2015

AdenoPlus point-of-care test for diagnosing adenoviral conjunctivitis (MIB46)

Advice on the use of the AdenoPlus point-of-care test for diagnosing adenoviral conjunctivitis to aid local decision-making

Medtech innovation briefing Published December 2015

PneuX for preventing ventilator-associated pneumonia in intensive care (MIB45)

Advice on the use of PneuX for preventing ventilator-associated pneumonia in intensive care to aid local decision-making

Medtech innovation briefing Published November 2015

ATEC system for vacuum-assisted breast biopsy (MIB43)

Advice on the use of the ATEC system for vacuum-assisted breast biopsy to aid local decision-making

Medtech innovation briefing Published November 2015

PROPATEN heparin-bonded vascular graft for peripheral arterial disease (MIB42)

Advice on the use of the PROPATEN heparin-bonded vascular graft for treating peripheral arterial disease to aid local decision-making

Medtech innovation briefing Published October 2015

Active B12 assay for diagnosing vitamin B12 deficiency (MIB40)

Advice on the use of the Active B12 assay for diagnosing vitamin B12 deficiency to aid local decision-making

Medtech innovation briefing Published September 2015

CareLink network service for remote monitoring of people with cardiac devices (MIB64)

Advice on the use of the CareLink network service for monitoring cardiac devices to aid local decision-making

Medtech innovation briefing Published May 2016

SIR-Spheres for treating inoperable hepatocellular carcinoma (MIB63)

Advice on the use of SIR-Spheres for treating inoperable hepatocellular carcinoma (HCC) (liver cancer) to aid local decision-making

Medtech innovation briefing Published March 2016

TheraSphere for treating operable and inoperable hepatocellular carcinoma (MIB62)

Advice on the use of TheraSphere for treating operable and inoperable hepatocellular carcinoma (liver cancer) to aid local decision-making

Medtech innovation briefing Published March 2016

ThermoCool SmartTouch catheter for percutaneous radiofrequency ablation in atrial fibrillation (MIB61)

Advice on the use of the ThermoCool SmartTouch catheter for percutaneous radiofrequency ablation in atrial fibrillation to aid local decision-making

Medtech innovation briefing Published March 2016

TactiCath Quartz catheter for percutaneous radiofrequency ablation in atrial fibrillation (MIB60)

Advice on the use of the TactiCath Quartz catheter for percutaneous radiofrequency ablation in atrial fibrillation to aid local decision-making

Medtech innovation briefing Published March 2016

AccuVein AV400 for vein visualisation (MIB6)

Advice on the use of AccuVein AV400 for vein visualisation (peripheral venous access) to aid local decision-making

Medtech innovation briefing Published June 2014

Mersey Burns for calculating fluid resuscitation volume when managing burns (MIB58)

Advice on the use of the Mersey Burns app for calculating fluid resuscitation when managing burns to aid local decision-making

Medtech innovation briefing Published March 2016

Icare rebound tonometer to measure intraocular pressure (MIB57)

Advice on the use of the Icare rebound tonometer to measure intraocular pressure and assess the risk of developing glaucoma to aid local decision-making

Medtech innovation briefing Published March 2016

ODFS Pace and Pace XL functional electrical stimulation devices for treating drop foot (MIB56)

Advice on the use of ODFS Pace and Pace XL functional electrical stimulation devices for treating drop foot to aid local decision-making

Medtech innovation briefing Published March 2016

ClearWay RX for drug delivery to coronary artery thrombotic lesions (MIB55)

Advice ClearWay RX for drug delivery to coronary artery thrombotic lesions to aid local decision-making

Medtech innovation briefing Published March 2016

Somatom Definition Edge CT scanner for imaging coronary artery disease in adults in whom imaging is difficult (MIB54)

Advice on the use of the Somatom Definition Edge CT scanner for imaging coronary artery disease to aid local decision-making

Medtech innovation briefing Published March 2016 Last updated July 2017

Aquilion PRIME CT scanner for imaging coronary artery disease in adults in whom imaging is difficult (MIB53)

Advice on the use of the Aquilion PRIME CT scanner for imaging coronary artery disease to aid local decision-making

Medtech innovation briefing Published March 2016 Last updated July 2017

The PolySoft hernia patch used with the ONSTEP technique to treat inguinal hernias (MIB9)

Advice on the use of the PolySoft hernia patch with the ONSTEP technique for treating inguinal hernias to aid local decision-making

Medtech innovation briefing Published August 2014

Impella 2.5 for haemodynamic support during high-risk percutaneous coronary interventions (MIB89)

Advice on the use of Impella 2.5 for haemodynamic support during high-risk percutaneous coronary interventions to aid local decision-making

Medtech innovation briefing Published November 2016

Sternal Talon for sternal closure in cardiothoracic surgery (MIB88)

Advice on the use of Sternal Talon for closing the sternum in cardiothoracic surgery to aid local decision-making

Medtech innovation briefing Published November 2016

CytoSorb therapy for sepsis (MIB87)

Advice on the use of CytoSorb therapy for treating sepsis to aid local decision-making

Medtech innovation briefing Published November 2016

OCS Heart system for heart transplant (MIB86)

Advice on the use of OCS Heart system for monitoring and preserving donor hearts to aid local decision-making

Medtech innovation briefing Published November 2016

The Airsonett temperature-controlled laminar airflow device for persistent allergic asthma (MIB8)

Advice on the use of the Airsonett temperature-controlled laminar airflow device for persistent allergic asthma to aid local decision-making

Medtech innovation briefing Published August 2014

OSNA for colon cancer staging (MIB77)

Advice on the use of OSNA in vitro diagnostic molecular assay system for staging colon cancer to aid local decision-making

Medtech innovation briefing Published August 2016

Axxent electronic brachytherapy system for early stage breast cancer (MIB76)

Advice on the use of the Axxent electronic brachytherapy system for treating early stage breast cancer to aid local decision-making

Medtech innovation briefing Published August 2016