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Non-Hodgkin's lymphoma: rituximab subcutaneous injection (ESNM46)

Summary of the evidence on rituximab subcutaneous injection for non-Hodgkin's lymphoma in adults to inform local NHS planning and decision-making

Evidence summary Published September 2014

Schizophrenia: aripiprazole prolonged-release suspension for injection (ESNM39)

Summary of the evidence on aripiprazole prolonged-release suspension for injection for schizophrenia to inform local NHS planning and decision-making

Evidence summary Published March 2014

Gouty arthritis: canakinumab (ESNM23)

Summary of the evidence on canakinumab for treating gouty arthritis (gout) to inform local NHS planning and decision-making

Evidence summary Published July 2013

Chronic obstructive pulmonary disease: indacaterol/glycopyrronium (Ultibro Breezhaler) (ESNM33)

Summary of the evidence on the indacaterol/glycopyrronium (Ultibro Breezhaler) for relieving the symptoms of chronic obstructive pulmonary disease (COPD)..

Evidence summary Published February 2014 Last updated March 2014

Partial seizures in children and young people with epilepsy: zonisamide as adjunctive therapy (ESNM37)

Summary of the evidence on zonisamide as adjunctive therapy for partial seizures in children and young people (aged 6–17 years) with epilepsy..

Evidence summary Published March 2014

Prostate cancer: triptorelin (Decapeptyl SR) (ESNM30)

Summary of the evidence on triptorelin (Decapeptyl SR) for treating prostate cancer to inform local NHS planning and decision-making

Evidence summary Published January 2014

Oxyzyme and Iodozyme 2-layer hydrogel wound dressings with iodine for treating chronic wounds (MIB11)

Advice on the use of Oxyzyme and Iodozyme 2-layer hydrogel wound dressings with iodine for treating chronic wounds to aid local decision-making

Medtech innovation briefing Published November 2014

First-choice antidepressant use in adults with depression or generalised anxiety disorder (KTT8)

KTT8 First-choice antidepressant use in adults with depression or generalised anxiety disorder Options for local implementation

Key therapeutic topic Published January 2015 Last updated February 2016

The Arrow OnControl powered bone marrow biopsy system for bone marrow aspiration and biopsy (MIB19)

Advice on the use of the Arrow OnControl powered bone marrow biopsy system for bone marrow aspiration and biopsy to aid local decision-making

Medtech innovation briefing Published February 2015

Mollii suit for spasticity (MIB100)

Advice on the use of Mollii suit (formerly Elektrodress; a therapeutic electrical stimulation jacket and trousers) for spasticity to aid local decision-making

Medtech innovation briefing Published March 2017

Anticoagulants, including direct-acting oral anticoagulants (DOACs) (KTT16)

KTT16 Anticoagulants, including direct-acting oral anticoagulants (DOACs) Key points

Key therapeutic topic Published February 2016 Last updated September 2019

Lipid-modifying drugs (KTT3)

KTT3 Lipid-modifying drugs Key points The NICE guideline on cardiovascular disease:

Key therapeutic topic Published January 2015 Last updated September 2019

Antipsychotics in people living with dementia (KTT7)

KTT7 Antipsychotics in people living with dementia Key points The risks and limited

Key therapeutic topic Published January 2015 Last updated September 2019

End-tidal Control software for use with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia (MIB10)

Advice on the use of End-tidal Control software with Aisys closed circuit anaesthesia systems for automated gas control during general anaesthesia..

Medtech innovation briefing Published September 2014

LipiFlow thermal pulsation treatment for dry eyes caused by blocked meibomian glands (MIB29)

Advice on the use of the LipiFlow thermal pulsation treatment for dry eyes caused by blocked meibomian glands to aid local decision-making

Medtech innovation briefing Published April 2015

VAAFT for treating anal fistulae (MIB102)

Advice on the use of VAAFT for treating anal fistulae to aid local decision-making

Medtech innovation briefing Published April 2017

Zio Service for detecting cardiac arrhythmias (MIB101)

Advice on the use of the Zio Service (a remote cardiac monitoring system) for detecting cardiac arrhythmias to aid local decision-making

Medtech innovation briefing Published March 2017

Hormone-sensitive metastatic prostate cancer: docetaxel (ESUOM50)

Summary of the evidence on docetaxel for treating hormone-sensitive metastatic prostate cancer to inform local NHS planning and decision-making

Evidence summary Published January 2016

Wound care products (KTT14)

KTT14 Wound care products Key points A large number of wound dressings are available

Key therapeutic topic Published January 2015 Last updated September 2019

Infantile haemangioma: topical timolol (ESUOM47)

Summary of the evidence on topical timolol for treating infantile haemangioma (strawberry marks) to inform local NHS planning and decision-making

Evidence summary Published August 2015

Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI (KTT17)

KTT17 Acute kidney injury (AKI): use of medicines in people with or at increased risk of AKI Key points

Key therapeutic topic Published February 2016 Last updated September 2019

Hypnotics (KTT6)

KTT6 Hypnotics Key points The risks associated with hypnotics (including melatonin)

Key therapeutic topic Published January 2015 Last updated September 2019

Cystic fibrosis: long-term azithromycin (ESUOM37)

Summary of the evidence on long-term azithromycinoral for treating cystic fibrosis (CF) to inform local NHS planning and decision-making

Evidence summary Published November 2014

Symptoms of peripheral arterial disease: ramipril (ESUOM45)

Summary of the evidence on ramipril for relieving the symptoms of peripheral arterial disease (PAD) to inform local NHS planning and decision-making

Evidence summary Published June 2015

Psychotropic medicines in people with learning disabilities whose behaviour challenges (KTT19)

KTT19 Psychotropic medicines in people with learning disabilities whose behaviour challenges Key points

Key therapeutic topic Published January 2017 Last updated September 2019

Non-steroidal anti-inflammatory drugs (KTT13)

KTT13 Non-steroidal anti-inflammatory drugs Options for local implementation Review

Key therapeutic topic Published January 2015 Last updated February 2018

Laxatives (KTT1)

KTT1 Laxatives Options for local implementation Review and, if appropriate, revise prescribing

Key therapeutic topic Published January 2015

Chronic urticaria: off-label doses of cetirizine (ESUOM31)

Summary of the evidence on off-label doses of cetirizine for chronic urticaria (hives) to inform local NHS planning and decision-making

Evidence summary Published July 2014

Safer insulin prescribing (KTT20)

KTT20 Safer insulin prescribing Key points Several new insulin products have been launched

Key therapeutic topic Published January 2017 Last updated September 2019

Scleroderma: oral mycophenolate (ESUOM32)

Summary of the evidence on oral mycophenolate for systemic sclerosis (scleroderma) to inform local NHS planning and decision-making

Evidence summary Published July 2014

Hemosep for cell salvage (MIB103)

MIB103 Hemosep for cell salvage Summary The technology described in this briefing

Medtech innovation briefing Published May 2017

The NxStage System One NX1000‑1 home haemodialysis device for renal replacement therapy in chronic kidney disease (MIB12)

Advice on the use of the NxStage System One NX1000-1 home haemodialysis device for renal replacement therapy in chronic kidney disease (CKD)..

Medtech innovation briefing Published November 2014

The Juxta CURES adjustable compression system for treating venous leg ulcers (MIB25)

Advice on the use of the Juxta CURES adjustable compression system for treating venous leg ulcers to aid local decision-making

Medtech innovation briefing Published March 2015

Preventing recurrent hypomagnesaemia: oral magnesium glycerophosphate (ESUOM4)

Summary of the evidence on oral magnesium glycerophosphate for preventing recurrent hypomagnesaemia to inform local NHS planning and decision-making

Evidence summary Published January 2013

Medicines optimisation in chronic pain (KTT21)

KTT21 Medicines optimisation in chronic pain Key points Controlling chronic pain can

Key therapeutic topic Published January 2017 Last updated September 2019

Management of aggression, agitation and behavioural disturbances in dementia: carbamazepine (ESUOM40)

Summary of the evidence on carbamazepine for managing aggression, agitation and behavioural disturbances in people with dementia..

Evidence summary Published March 2015

C3 glomerulopathy in the native kidney: eculizumab (ESUOM49)

Summary of the evidence on eculizumab for treating C3 glomerulopathy in the native kidney inform local NHS planning and decision-making

Evidence summary Published December 2015

Minocycline (KTT11)

KTT11 Minocycline Options for local implementation Review and, if appropriate, revise

Key therapeutic topic Published January 2015

Active B12 assay for diagnosing vitamin B12 deficiency (MIB40)

Advice on the use of the Active B12 assay for diagnosing vitamin B12 deficiency to aid local decision-making

Medtech innovation briefing Published September 2015

AdenoPlus point-of-care test for diagnosing adenoviral conjunctivitis (MIB46)

Advice on the use of the AdenoPlus point-of-care test for diagnosing adenoviral conjunctivitis to aid local decision-making

Medtech innovation briefing Published December 2015

Secca System for faecal incontinence (MIB66)

Advice on the use of the Secca system for treating faecal incontinence to aid local decision-making

Medtech innovation briefing Published May 2016

Chronic anal fissure: 0.2% topical glyceryl trinitrate ointment (ESUOM7)

Summary of the evidence on 0.2% topical glyceryl trinitrate ointment for chronic anal fissure to inform local NHS planning and decision-making

Evidence summary Published March 2013

Non-cystic fibrosis bronchiectasis: long-term azithromycin (ESUOM38)

Summary of the evidence on long-term azithromycin for treating non-cystic fibrosis bronchiectasis to inform local NHS planning and decision-making

Evidence summary Published November 2014

Prevention of recurrence of C3 glomerulopathy post-transplant: eculizumab (ESUOM44)

Summary of the evidence on eculizumab to prevent the recurrence of C3 glomerulopathy post-transplant to inform local NHS planning and decision-making

Evidence summary Published June 2015

The Oncentra Prostate v4.x for ultrasound‑guided real‑time HDR brachytherapy in men with localised prostate cancer (MIB16)

Advice on the use of Oncentra Prostate v4.x for ultrasound-guided real-time HDR brachytherapy in men with localised prostate cancer to aid local decision-making

Medtech innovation briefing Published December 2014

Aixplorer ShearWave Elastography for ultrasound imaging and assessing suspicious breast lesions (MIB15)

Advice on the use of Aixplorer ShearWave Elastography for ultrasound imaging and assessing suspicious breast lesions to aid local decision-making

Medtech innovation briefing Published December 2014

Pulmonary hypertension in neonates: sildenafil (ESUOM51)

Summary of the evidence on sildenafil for treating pulmonary hypertension in neonates to inform local NHS planning and decision-making

Evidence summary Published March 2016

Management of vomiting in children and young people with gastroenteritis: ondansetron (ESUOM34)

Summary of the evidence on ondansetron for the management of vomiting in children and young people with acute gastroenteritis...

Evidence summary Published October 2014

Fatigue in multiple sclerosis: modafinil (ESUOM9)

Summary of the evidence on modafinil for treating fatigue in multiple sclerosis (MS) to inform local NHS planning and decision-making

Evidence summary Published April 2013

Ekso exoskeleton for rehabilitation in people with neurological weakness or paralysis (MIB93)

Advice on the use of the Ekso exoskeleton for rehabilitation in people with neurological weakness or paralysis to aid local decision-making

Medtech innovation briefing Published January 2017