Updating results

Opioid dependence: buprenorphine prolonged-release injection (Buvidal) (ES19)

Summary of the evidence on buprenorphine prolonged-release subcutaneous injection (Buvidal) for opioid dependence to inform local NHS

Evidence summary Published February 2019

Personalisation and risk markers:- What prognostic and prescriptive factors are important in determining the choice of PTSD treatment?

Recommendation ID NG116/4 Question Personalisation and risk markers:- What prognostic and prescriptive factors are important in determining

Research recommendation Published February 2019

Prophylactic antibiotics for preventing exacerbations: - What is the long-term clinical and cost effectiveness of prophylactic antibiotics for people with stable COPD who are at high risk of exacerbations?

Recommendation ID NG115/7 Question Prophylactic antibiotics for preventing exacerbations: - What is the long-term clinical and cost effectiveness

Research recommendation Published February 2019

Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of seasonal versus continuous prophylactic antibiotics for people with stable COPD who are at high risk of exacerbations?

Recommendation ID NG115/9 Question Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of seasonal

Research recommendation Published February 2019

Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of different antibiotics, doses and regimens of prophylactic antibiotics for people with stable COPD who are at high risk of exacerbations?

Recommendation ID NG115/8 Question Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of different

Research recommendation Published February 2019

Trauma-informed approaches:- What is the clinical and cost effectiveness of trauma-informed care or trauma-informed approaches?

Recommendation ID NG116/3 Question Trauma-informed approaches:- What is the clinical and cost effectiveness of trauma-informed care or

Research recommendation Published February 2019

Stepped care for post-traumatic stress disorder:- What is the clinical and cost effectiveness of stepped care for post-traumatic stress disorder (PTSD)?

Recommendation ID NG116/1 Question Stepped care for post-traumatic stress disorder:- What is the clinical and cost effectiveness of stepped

Research recommendation Published February 2019

Sequencing and further line treatment:- What is the clinical and cost effectiveness of sequencing and further line treatment in PTSD?

Recommendation ID NG116/2 Question Sequencing and further line treatment:- What is the clinical and cost effectiveness of sequencing and

Research recommendation Published February 2019

Complex PTSD:- What is the clinical and cost effectiveness of interventions to deliver stabilisation and reintegration for people with complex PTSD?

Recommendation ID NG116/5 Question Complex PTSD:- What is the clinical and cost effectiveness of interventions to deliver stabilisation

Research recommendation Published February 2019

Emotional freedom techniques:- What is the clinical and cost effectiveness of emotional freedom techniques (EFT) for the treatment of PTSD in adults?

Recommendation ID NG116/6 Question Emotional freedom techniques:- What is the clinical and cost effectiveness of emotional freedom techniques

Research recommendation Published February 2019

Pulmonary hypertension:- What are the most clinical and cost-effective treatments for pulmonary hypertension in people with COPD?

Recommendation ID NG115/10 Question Pulmonary hypertension:- What are the most clinical and cost-effective treatments for pulmonary hypertension

Research recommendation Published February 2019

Diagnosing COPD: -  What are the characteristics of people diagnosed with COPD as a result of an incidental finding ofemphysema on a CT scan, compared with those diagnosed with symptoms?

Recommendation ID NG115/6 Question Diagnosing COPD: - What are the characteristics of people diagnosed with COPD as a result of an incidental

Research recommendation Published February 2019

Mucolytic therapy:- In people with COPD, does mucolytic drug therapy prevent exacerbations in comparison with placebo and other therapies?

Recommendation ID NG115/11 Question Mucolytic therapy:- In people with COPD, does mucolytic drug therapy prevent exacerbations in comparison

Research recommendation Published February 2019

Axumin for functional imaging of prostate cancer recurrence (MIB172)

Advice on the use of Axumin for functional imaging of prostate cancer recurrence to aid local decision making

Medtech innovation briefing Published February 2019

Prophylactic antibiotics for preventing exacerbations:- Which subgroups of people with stable COPD who are at high risk of exacerbations are most likely to benefit from prophylactic antibiotics?

Recommendation ID NG115/5 Question Prophylactic antibiotics for preventing exacerbations:- Which subgroups of people with stable COPD who

Research recommendation Published February 2019

Inhaled therapies for people with COPD and asthma- What is the clinical and cost effectiveness of inhaled therapies (bronchodilators and/or inhaled corticosteroids) in people with both stable COPD and asthma?

Recommendation ID NG115/3 Question Inhaled therapies for people with COPD and asthma- What is the clinical and cost effectiveness of inhaled

Research recommendation Published February 2019

Inhaled corticosteroid responsiveness:- What features predict inhaled corticosteroid responsiveness most accurately in people with COPD?

Recommendation ID NG115/4 Question Inhaled corticosteroid responsiveness:- What features predict inhaled corticosteroid responsiveness most

Research recommendation Published February 2019

StoneChecker for kidney stone evaluation (MIB171)

Advice on the use of StoneChecker for kidney stone evaluation to aid local decision making

Medtech innovation briefing Published February 2019

Further research on transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia in adults should address patient selection, variations in technique, the need for retreatments and long-term outcomes.

Recommendation ID IPG634/1 Question Further research on transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia

Research recommendation Published January 2019

Path Finder for freezing of gait in people with Parkinson's disease (MIB170)

Advice on the use of Path Finder for freezing of gait in people with Parkinson’s disease to aid local decision-making

Medtech innovation briefing Published January 2019

RT300 for spinal cord injury rehabilitation (MIB169)

Advice on the use of RT300 for spinal cord injury rehabilitation to aid local decision making

Medtech innovation briefing Published January 2019

LiMAx system for assessing the functional capacity of the liver (MIB168)

Advice on the use of LiMAx system for assessing the functional capacity of the liver to aid local decision making

Medtech innovation briefing Published January 2019

Further research is needed on the benefits and consequences of detecting preclinical diabetic peripheral neuropathy.

Recommendation ID MTG38/1 Question Further research is needed on the benefits and consequences of detecting preclinical diabetic peripheral

Research recommendation Published January 2019

Further research on percutaneous insertion of a temporary heart pump for left ventricular haemodynamic support in high-risk percutaneous coronary interventions should report details of patient selection and subsequent management.

Recommendation ID IPG633/1 Question Further research on percutaneous insertion of a temporary heart pump for left ventricular haemodynamic

Research recommendation Published December 2018

Anticholinergic burden:- Does actively reducing anticholinergic burden in people living with dementia improve cognitive outcomes compared with usual care?

Recommendation ID NG97/3 Question Anticholinergic burden:- Does actively reducing anticholinergic burden in people living with dementia

Research recommendation Published December 2018

Video laryngoscopes to help intubation in people with difficult airways (MIB167)

Advice on the use of video laryngoscopy to help intubation in people with difficult airways to aid local decision-making

Medtech innovation briefing Published December 2018

Further research on subcutaneous automated low-flow pump implantation for refractory ascites should report details of patient selection, the frequency of pump-related complications, and the need for regular albumin infusions.

Recommendation ID IPG631/1 Question Further research on subcutaneous automated low-flow pump implantation for refractory ascites should

Research recommendation Published December 2018

Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears should address patient selection, type of graft and technique used,long-term outcomes including shoulder function, and patient-reported outcome measures.

Recommendation ID IPG619/1 Question Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears

Research recommendation Published December 2018

Clinicians should enter details about all patients having selective internal radiation therapy (SIRT) for unresectable primary intrahepatic cholangiocarcinoma onto a suitable registry.

Recommendation ID IPG630/2 Question Clinicians should enter details about all patients having selective internal radiation therapy (SIRT)

Research recommendation Published December 2018

Timing of pre-emptive transplant:- What is the most clinical and cost-effective strategy for timing of pre-emptive transplantation?

Recommendation ID NG107/2 Question Timing of pre-emptive transplant:- What is the most clinical and cost-effective strategy for timing of

Research recommendation Published December 2018

Frequency of review:- What is the most clinical and cost-effective frequency of review for people on peritoneal dialysis, haemodiafiltration, haemodialysis or conservative management?

Recommendation ID NG107/4 Question Frequency of review:- What is the most clinical and cost-effective frequency of review for people on

Research recommendation Published December 2018

Advocacy and support for decision-making:- What is the effectiveness, cost effectiveness and acceptability of advocacy as a means of supporting people to make decisions?

Recommendation ID NG108/3 Question Advocacy and support for decision-making:- What is the effectiveness, cost effectiveness and acceptability

Research recommendation Published December 2018

Acute haemodialysis versus acute peritoneal dialysis:- What is the clinical and cost effectiveness of initial haemodialysis versus initial peritoneal dialysis for people who start dialysis in an unplanned way?

Recommendation ID NG107/3 Question Acute haemodialysis versus acute peritoneal dialysis:- What is the clinical and cost effectiveness of

Research recommendation Published December 2018

Coordinating care:- What is the clinical and cost effectiveness of having keyworkers present in the context of renal replacement therapy (RRT)?

Recommendation ID NG107/5 Question Coordinating care:- What is the clinical and cost effectiveness of having keyworkers present in the context

Research recommendation Published December 2018

Cardiac assessment:- What is the clinical and cost effectiveness of cardiac assessment before transplantation?

Recommendation ID NG107/1 Question Cardiac assessment:- What is the clinical and cost effectiveness of cardiac assessment before transplantation

Research recommendation Published December 2018

Using mental capacity assessment tools to assess capacity:- What is the accuracy and/or effectiveness, cost effectiveness and acceptability of mental capacity assessment tools that are compliant with the Mental Capacity Act 2005?

Recommendation ID NG108/4 Question Using mental capacity assessment tools to assess capacity:- What is the accuracy and/or effectiveness

Research recommendation Published December 2018

Components of a mental capacity assessment:- What are the components of an effective assessment of mental capacity to make a decision (for example checklists, memory aids or standardised documentation)?

Recommendation ID NG108/5 Question Components of a mental capacity assessment:- What are the components of an effective assessment of mental

Research recommendation Published December 2018

The impact of atrial fibrillation on the natriuretic peptide threshold for diagnosing heart failure:- What is the optimal NT-proBNP threshold for the diagnosis of heart failure in people with atrial fibrillation?

Recommendation ID NG106/3 Question The impact of atrial fibrillation on the natriuretic peptide threshold for diagnosing heart failure:- What

Research recommendation Published December 2018

Cardiac MRI versus other imaging techniques for diagnosing heart failure:- What is the optimal imaging technique for the diagnosis of heart failure?

Recommendation ID NG106/2 Question Cardiac MRI versus other imaging techniques for diagnosing heart failure:- What is the optimal imaging

Research recommendation Published December 2018

Speed of intravenous fluid resuscitation for people with acute pancreatitis:- What is the most clinically effective and cost-effective speed of administration of intravenous fluid for resuscitation in people with acute pancreatitis?

Recommendation ID NG104/2 Question Speed of intravenous fluid resuscitation for people with acute pancreatitis:- What is the most clinically

Research recommendation Published December 2018

Pain management: small duct disease:- What is the most clinically effective and cost-effective intervention for managing small duct disease (in the absence of pancreatic duct obstruction, inflammatory mass or pseudocyst) in people with chronic pancreatitis presenting with pain?

Recommendation ID NG104/4 Question Pain management: small duct disease:- What is the most clinically effective and cost-effective intervention

Research recommendation Published December 2018

Management of type 3c diabetes:- What is the most clinically effective and cost-effective insulin regimen to minimise hypo- and hyperglycaemia for type 3c diabetes secondary to pancreatitis?

Recommendation ID NG104/5 Question Management of type 3c diabetes:- What is the most clinically effective and cost-effective insulin regimen

Research recommendation Published December 2018

Suicide prevention in custodial and detention settings:- What interventions are effective and cost effective in reducing suicide rates in custodial and residential settings?

Recommendation ID NG105/3 Question Suicide prevention in custodial and detention settings:- What interventions are effective and cost effective

Research recommendation Published December 2018