Updating results

CADScor system for ruling out coronary artery disease in people with symptoms of stable coronary artery disease (MIB174)

Advice on the use of CADScor system for ruling out coronary artery disease in people with stable coronary artery disease symptoms to aid local decision-making

Medtech innovation briefing Published March 2019

Prevena incision management system for closed surgical incisions (MIB173)

Advice on the use of Prevena incision management system for closed surgical incisions to aid local decision making

Medtech innovation briefing Published February 2019

Further research on platelet-rich plasma injections for knee osteoarthritis should be in the form of randomised controlled trials with medium- to long-term follow-up, including validated measures of knee function and patient-reported outcomes.

Recommendation ID IPG637/1 Question Further research on platelet-rich plasma injections for knee osteoarthritis should be in the form of

Research recommendation Published February 2019

Further research on ex-situ machine perfusion for extracorporeal preservation of livers for transplantation should report the exact method of perfusion used (such ashypothermic or normothermic), graft survival and the use of marginal grafts.

Recommendation ID IPG636/1 Question Further research on ex-situ machine perfusion for extracorporeal preservation of livers for transplantation

Research recommendation Published February 2019

Further research on electrically stimulated intravesical chemotherapy for nonmuscle-invasive bladder cancer should include randomised controlled trials compared withstandard care, which should report details of patient selection.

Recommendation ID IPG638/1 Question Further research on electrically stimulated intravesical chemotherapy for nonmuscle-invasive bladder

Research recommendation Published February 2019

Opioid dependence: buprenorphine prolonged-release injection (Buvidal) (ES19)

Summary of the evidence on buprenorphine prolonged-release subcutaneous injection (Buvidal) for opioid dependence to inform local NHS

Evidence summary Published February 2019

Personalisation and risk markers:- What prognostic and prescriptive factors are important in determining the choice of PTSD treatment?

Recommendation ID NG116/4 Question Personalisation and risk markers:- What prognostic and prescriptive factors are important in determining

Research recommendation Published February 2019

Prophylactic antibiotics for preventing exacerbations: - What is the long-term clinical and cost effectiveness of prophylactic antibiotics for people with stable COPD who are at high risk of exacerbations?

Recommendation ID NG115/7 Question Prophylactic antibiotics for preventing exacerbations: - What is the long-term clinical and cost effectiveness

Research recommendation Published February 2019

Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of seasonal versus continuous prophylactic antibiotics for people with stable COPD who are at high risk of exacerbations?

Recommendation ID NG115/9 Question Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of seasonal

Research recommendation Published February 2019

Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of different antibiotics, doses and regimens of prophylactic antibiotics for people with stable COPD who are at high risk of exacerbations?

Recommendation ID NG115/8 Question Prophylactic antibiotics for preventing exacerbations:- What is the comparative effectiveness of different

Research recommendation Published February 2019

Trauma-informed approaches:- What is the clinical and cost effectiveness of trauma-informed care or trauma-informed approaches?

Recommendation ID NG116/3 Question Trauma-informed approaches:- What is the clinical and cost effectiveness of trauma-informed care or

Research recommendation Published February 2019

Stepped care for post-traumatic stress disorder:- What is the clinical and cost effectiveness of stepped care for post-traumatic stress disorder (PTSD)?

Recommendation ID NG116/1 Question Stepped care for post-traumatic stress disorder:- What is the clinical and cost effectiveness of stepped

Research recommendation Published February 2019

Sequencing and further line treatment:- What is the clinical and cost effectiveness of sequencing and further line treatment in PTSD?

Recommendation ID NG116/2 Question Sequencing and further line treatment:- What is the clinical and cost effectiveness of sequencing and

Research recommendation Published February 2019

Complex PTSD:- What is the clinical and cost effectiveness of interventions to deliver stabilisation and reintegration for people with complex PTSD?

Recommendation ID NG116/5 Question Complex PTSD:- What is the clinical and cost effectiveness of interventions to deliver stabilisation

Research recommendation Published February 2019

Emotional freedom techniques:- What is the clinical and cost effectiveness of emotional freedom techniques (EFT) for the treatment of PTSD in adults?

Recommendation ID NG116/6 Question Emotional freedom techniques:- What is the clinical and cost effectiveness of emotional freedom techniques

Research recommendation Published February 2019

Pulmonary hypertension:- What are the most clinical and cost-effective treatments for pulmonary hypertension in people with COPD?

Recommendation ID NG115/10 Question Pulmonary hypertension:- What are the most clinical and cost-effective treatments for pulmonary hypertension

Research recommendation Published February 2019

Diagnosing COPD: -  What are the characteristics of people diagnosed with COPD as a result of an incidental finding ofemphysema on a CT scan, compared with those diagnosed with symptoms?

Recommendation ID NG115/6 Question Diagnosing COPD: - What are the characteristics of people diagnosed with COPD as a result of an incidental

Research recommendation Published February 2019

Mucolytic therapy:- In people with COPD, does mucolytic drug therapy prevent exacerbations in comparison with placebo and other therapies?

Recommendation ID NG115/11 Question Mucolytic therapy:- In people with COPD, does mucolytic drug therapy prevent exacerbations in comparison

Research recommendation Published February 2019

Axumin for functional imaging of prostate cancer recurrence (MIB172)

Advice on the use of Axumin for functional imaging of prostate cancer recurrence to aid local decision making

Medtech innovation briefing Published February 2019

Prophylactic antibiotics for preventing exacerbations:- Which subgroups of people with stable COPD who are at high risk of exacerbations are most likely to benefit from prophylactic antibiotics?

Recommendation ID NG115/5 Question Prophylactic antibiotics for preventing exacerbations:- Which subgroups of people with stable COPD who

Research recommendation Published February 2019

Inhaled therapies for people with COPD and asthma- What is the clinical and cost effectiveness of inhaled therapies (bronchodilators and/or inhaled corticosteroids) in people with both stable COPD and asthma?

Recommendation ID NG115/3 Question Inhaled therapies for people with COPD and asthma- What is the clinical and cost effectiveness of inhaled

Research recommendation Published February 2019

Inhaled corticosteroid responsiveness:- What features predict inhaled corticosteroid responsiveness most accurately in people with COPD?

Recommendation ID NG115/4 Question Inhaled corticosteroid responsiveness:- What features predict inhaled corticosteroid responsiveness most

Research recommendation Published February 2019

StoneChecker for kidney stone evaluation (MIB171)

Advice on the use of StoneChecker for kidney stone evaluation to aid local decision making

Medtech innovation briefing Published February 2019

Adoption of Peristeen at Alder Hey Children's Hospital

Shared learning Published January 2019

Further research on transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia in adults should address patient selection, variations in technique, the need for retreatments and long-term outcomes.

Recommendation ID IPG634/1 Question Further research on transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia

Research recommendation Published January 2019

Path Finder for freezing of gait in people with Parkinson's disease (MIB170)

Advice on the use of Path Finder for freezing of gait in people with Parkinson’s disease to aid local decision-making

Medtech innovation briefing Published January 2019

RT300 for spinal cord injury rehabilitation (MIB169)

Advice on the use of RT300 for spinal cord injury rehabilitation to aid local decision making

Medtech innovation briefing Published January 2019

LiMAx system for assessing the functional capacity of the liver (MIB168)

Advice on the use of LiMAx system for assessing the functional capacity of the liver to aid local decision making

Medtech innovation briefing Published January 2019

Further research is needed on the benefits and consequences of detecting preclinical diabetic peripheral neuropathy.

Recommendation ID MTG38/1 Question Further research is needed on the benefits and consequences of detecting preclinical diabetic peripheral

Research recommendation Published January 2019

Further research on subcutaneous automated low-flow pump implantation for refractory ascites should report details of patient selection, the frequency of pump-related complications, and the need for regular albumin infusions.

Recommendation ID IPG631/1 Question Further research on subcutaneous automated low-flow pump implantation for refractory ascites should

Research recommendation Published December 2018

Further research on percutaneous insertion of a temporary heart pump for left ventricular haemodynamic support in high-risk percutaneous coronary interventions should report details of patient selection and subsequent management.

Recommendation ID IPG633/1 Question Further research on percutaneous insertion of a temporary heart pump for left ventricular haemodynamic

Research recommendation Published December 2018

Anticholinergic burden:- Does actively reducing anticholinergic burden in people living with dementia improve cognitive outcomes compared with usual care?

Recommendation ID NG97/3 Question Anticholinergic burden:- Does actively reducing anticholinergic burden in people living with dementia

Research recommendation Published December 2018