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Decreasing pharmacological treatment:- In adults, young people and children with well-controlled asthma, what are the objective measurements and prognostic factors that indicate that a decrease in regular maintenance treatment is appropriate?

Recommendation ID NG80/9 Question Decreasing pharmacological treatment:- In adults, young people and children with well-controlled asthma

Research recommendation Published October 2018

Diagnosing asthma in adults (aged 17 and over):- What is the clinical and cost effectiveness of using an indirect bronchial challenge test with mannitol to diagnose asthma in adults (aged 17 and over)?

Recommendation ID NG80/2 Question Diagnosing asthma in adults (aged 17 and over):- What is the clinical and cost effectiveness of using

Research recommendation Published October 2018

An instrument to measure quality of life in people with glaucoma:- What instrument should be used to measure health related quality of life in people with glaucoma?

Recommendation ID NG81/3 Question An instrument to measure quality of life in people with glaucoma:- What instrument should be used to measure

Research recommendation Published October 2018

Relative effectiveness of interventions to support foster carers:- What is the relative effectiveness and cost effectiveness of the KEEP intervention for foster carersof abused or neglected children compared to other interventions?

Recommendation ID NG76/15 Question Relative effectiveness of interventions to support foster carers:- What is the relative effectiveness

Research recommendation Published October 2018

Quality of life in cataract surgery:- What vision-specific, quality-of-life measures best capture visual changes in a population with cataracts?

Recommendation ID NG77/2 Question Quality of life in cataract surgery:- What vision-specific, quality-of-life measures best capture visual

Research recommendation Published October 2018

Psychological assessment:- What is the most effective measure of psychological functioning to use as a test for thresholds of concern in people with cystic fibrosis?

Recommendation ID NG78/4 Question Psychological assessment:- What is the most effective measure of psychological functioning to use as a

Research recommendation Published October 2018

Peer support for children and young people who have been abused or neglected:- What peer support programmes are effective and cost effective in improving the wellbeing of children and young people who have been abused or neglected?

Recommendation ID NG76/16 Question Peer support for children and young people who have been abused or neglected:- What peer support programmes

Research recommendation Published October 2018

Mucoactive agents:- What is the most clinically and cost-effective dose of rhDNase (dornase alfa; recombinant human deoxyribonuclease) for people with cystic fibrosis?

Recommendation ID NG78/6 Question Mucoactive agents:- What is the most clinically and cost-effective dose of rhDNase (dornase alfa; recombinant

Research recommendation Published October 2018

Interventions with male foster carers and adoptive parents:- What interventions are effective and cost effective when working with male foster carers and adoptive parents who are caring for children and young people who have been abused in the past?

Recommendation ID NG76/11 Question Interventions with male foster carers and adoptive parents:- What interventions are effective and cost

Research recommendation Published October 2018

Interventions with fathers and male carers:- What interventions are effective and cost effective when working with fathers and male carers to improve their parenting in families where children are being, or have been, abused or neglected?

Recommendation ID NG76/10 Question Interventions with fathers and male carers:- What interventions are effective and cost effective when

Research recommendation Published October 2018

Interventions to prevent endophthalmitis:- What is the effectiveness of postoperative antibiotic drops to reduce rates of endophthalmitis after cataract surgery?

Recommendation ID NG77/5 Question Interventions to prevent endophthalmitis:- What is the effectiveness of postoperative antibiotic drops

Research recommendation Published October 2018

Interventions to manage cystoid macular oedema:- What is the most effective postoperative medical management for cystoid macular oedema?

Recommendation ID NG77/4 Question Interventions to manage cystoid macular oedema:- What is the most effective postoperative medical management

Research recommendation Published October 2018

Effective prevention of child abuse and neglect in the UK:- What interventions are effective and cost effective in the UK to prevent abuse and neglect of children and young people in families at risk of, or showing early signs of, abuse and neglect?

Recommendation ID NG76/5 Question Effective prevention of child abuse and neglect in the UK:- What interventions are effective and cost

Research recommendation Published October 2018

Effectiveness of web-based parenting programmes:- Are web-based parenting programmes effective and cost effective for improving parenting and preventing recurrence of child abuse and neglect in families where child abuse or neglect has occurred?

Recommendation ID NG76/14 Question Effectiveness of web-based parenting programmes:- Are web-based parenting programmes effective and cost

Research recommendation Published October 2018

Optimal time between referral and starting intermediate care:- What is the optimal time between referral to and starting intermediate care in terms of effectiveness and cost effectiveness and in terms of people's experiences?

Recommendation ID NG74/1 Question Optimal time between referral and starting intermediate care:- What is the optimal time between referral

Research recommendation Published October 2018

Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise) effective, compared with no specialist lifestyle interventions, for women with endometriosis?

Recommendation ID NG73/3 Question Lifestyle interventions (diet and exercise):- Are specialist lifestyle interventions (diet and exercise)

Research recommendation Published October 2018

Laparoscopic treatment of peritoneal endometriosis (excision or ablation):- Is laparoscopic treatment (excision or ablation) of peritoneal disease in isolation effective formanaging endometriosis-related pain?

Recommendation ID NG73/2 Question Laparoscopic treatment of peritoneal endometriosis (excision or ablation):- Is laparoscopic treatment

Research recommendation Published October 2018

Information and support:- What information and support interventions are effective to help women with endometriosis deal with their symptoms and improve their quality of lives?

Recommendation ID NG73/4 Question Information and support:- What information and support interventions are effective to help women with

Research recommendation Published October 2018

High energy liquid feed supplements:- Do high energy liquid feed supplements improve growth in children with faltering growth?

Recommendation ID NG75/1 Question High energy liquid feed supplements:- Do high energy liquid feed supplements improve growth in children

Research recommendation Published October 2018

Further research should give details of patient selection, patient-reported outcomes and long-term effects including survival and quality of life. NICE may update the guidance on publication of further evidence.

Recommendation ID IPG594/1 Question Further research should give details of patient selection, patient-reported outcomes and long-term effects

Research recommendation Published October 2018

Frequency of monitoring:- How frequently should children be measured to identify faltering growth?

Recommendation ID NG75/4 Question Frequency of monitoring:- How frequently should children be measured to identify faltering growth?

Research recommendation Published October 2018

Feeding interventions for the management of neonatal weight loss:- What is the effectiveness of feeding interventions compared with usual care/advice for breastfedneonates (up to 28 days old) with weight loss of greater than 10%?

Recommendation ID NG75/2 Question Feeding interventions for the management of neonatal weight loss:- What is the effectiveness of feeding

Research recommendation Published October 2018

Duration and intensity of home-based intermediate care:- How effective and cost effective are different approaches, in terms of duration and intensity, to providing home-based intermediate care for adults?

Recommendation ID NG74/7 Question Duration and intensity of home-based intermediate care:- How effective and cost effective are different

Research recommendation Published October 2018

Dementia care:- How effective and cost effective is intermediate care including reablement for supporting people living with dementia?

Recommendation ID NG74/4 Question Dementia care:- How effective and cost effective is intermediate care including reablement for supporting

Research recommendation Published October 2018

Crisis response:- What are the barriers and facilitators to providing an effective and cost effective crisis response service, with particular reference to different models for structuring delivery of this service?

Recommendation ID NG74/3 Question Crisis response:- What are the barriers and facilitators to providing an effective and cost effective

Research recommendation Published October 2018

Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual care/advice for children with faltering growth?

Recommendation ID NG75/3 Question Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual

Research recommendation Published October 2018

A single point of access for intermediate care:- How effective and cost effective is introducing a single point of access to intermediate care?

Recommendation ID NG74/6 Question A single point of access for intermediate care:- How effective and cost effective is introducing a single

Research recommendation Published October 2018

Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does enhanced developmental support and surveillance improve outcomes for the parents and carers of children born preterm?

Recommendation ID NG72/5 Question Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does

Research recommendation Published October 2018

Trials that evaluate utility values (using generic preference-based measures) in children and young people with severe psoriasis are needed to better inform future cost–utility analyses.

Recommendation ID TA455/1 Question Trials that evaluate utility values (using generic preference-based measures) in children and young people

Research recommendation Published October 2018

Rapid eye movement sleep behaviour disorder treatment:- What is the best first-line treatment for rapid eye movement sleep behaviour disorder (RBD) in people with Parkinson's disease?

Recommendation ID NG71/4 Question Rapid eye movement sleep behaviour disorder treatment:- What is the best first-line treatment for rapid

Research recommendation Published October 2018

Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared with atypical antipsychotic drugs for treating psychotic symptoms (particularly hallucinations and delusions) associated with Parkinson's disease?

Recommendation ID NG71/3 Question Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared

Research recommendation Published October 2018

Physiotherapy:- Does physiotherapy started early in the course of Parkinson's disease, as opposed to after motor symptom onset, confer benefits in terms of delaying symptom onset and/or reducing severity?

Recommendation ID NG71/5 Question Physiotherapy:- Does physiotherapy started early in the course of Parkinson's disease, as opposed to after

Research recommendation Published October 2018