Updating results

UrgoStart for treating diabetic foot ulcers and leg ulcers (MTG42)

Evidence-based recommendations on UrgoStart for treating diabetic foot ulcers and leg ulcers

Medical technologies guidance Published January 2019

Prostatic urethral temporary implant insertion for lower urinary tract symptoms caused by benign prostatic hyperplasia (IPG641)

Evidence-based recommendations on prostatic urethral temporary implant insertion for lower urinary tract symptoms caused by benign prostatic hyperplasia

Interventional procedures guidance Published January 2019

Percutaneous venoplasty for chronic cerebrospinal venous insufficiency in multiple sclerosis (IPG640)

Evidence-based recommendations on percutaneous venoplasty for chronic cerebrospinal venous insufficiency (CCSVI) in people with multiple sclerosis (MS)

Interventional procedures guidance Published January 2019

Laparoscopic cerclage for cervical incompetence to prevent late miscarriage or preterm birth (IPG639)

Evidence-based recommendations on laparoscopic cerclage for cervical incompetence to prevent late miscarriage or preterm birth

Interventional procedures guidance Published January 2019

Electrically stimulated intravesical chemotherapy for non-muscle-invasive bladder cancer (IPG638)

Evidence-based recommendations on electrically stimulated intravesical chemotherapy for non-muscle-invasive bladder cancer in adults

Interventional procedures guidance Published January 2019

NICE Scientific Advice launches collaborative programme with life sciences industry body

NICE has announced a collaboration with the body which represents life sciences organisations in the UK.

News Published January 2019 Last updated January 2019

Offer digital CBT to young people with mild depression, NICE says

Children and young people can be offered digital cognitive behavioural therapy (digital CBT, also known as computer CBT) as a first-line treatment for mild depression.

News Published January 2019 Last updated January 2019

Nivolumab for adjuvant treatment of completely resected melanoma with lymph node involvement or metastatic disease (TA558)

Evidence-based recommendations on nivolumab (Opdivo) for adjuvant treatment of completely resected melanoma with lymph node involvement or metastatic disease

Technology appraisal guidance Published January 2019

Senza spinal cord stimulation system for delivering HF10 therapy to treat chronic neuropathic pain (MTG41)

Evidence-based recommendations on the Senza spinal cord stimulation system for delivering HF10 therapy to treat chronic neuropathic pain

Medical technologies guidance Published January 2019

Platelet-rich plasma injections for knee osteoarthritis (IPG637)

Evidence-based recommendations on platelet-rich plasma injections for knee osteoarthritis in adults (deterioration of the articular cartilage and menisci)

Interventional procedures guidance Published January 2019

Axicabtagene ciloleucel for treating diffuse large B-cell lymphoma and primary mediastinal large B-cell lymphoma after 2 or more systemic therapies (TA559)

Evidence-based recommendations on axicabtagene ciloleucel (Yescarta) for treating diffuse large B-cell lymphoma and primary mediastinal large B-cell lymphoma

Technology appraisal guidance Published January 2019

Thousands of adults with chronic lymphocytic leukaemia to benefit from new treatment option

Thousands of people will benefit as NICE recommends venetoclax with rituximab for adults with relapsed or refractory chronic lymphocytic leukaemia.

News Published January 2019 Last updated January 2019

More donor livers could be used for transplantation thanks to exciting new development, NICE says

Procedure will extend the life of a donor liver by double the length of time compared to now

News Published January 2019 Last updated January 2019

Ex-situ machine perfusion for extracorporeal preservation of livers for transplantation (IPG636)

Evidence-based recommendations on ex-situ machine perfusion for extracorporeal preservation of livers for transplantation in people of all ages

Interventional procedures guidance Published January 2019

NICE guideline set to address variation in provision of services for adults with cerebral palsy

NICE has published its guideline on the care and support needs of adults with cerebral palsy.

News Published January 2019 Last updated January 2019

Cerebral palsy in adults (NG119)

This guideline covers care and support for adults with cerebral palsy. It aims to improve health and wellbeing, promote access to services and support participation and independent living.

NICE guideline Published January 2019

Sharing end of life decisions: Carrying out mum's wishes

Annabel Dawson, lay reviewer for National Institute for Health Research discussed the importance of end of life planning

News Published January 2019 Last updated January 2019

New migraine drug not cost-effective NICE says in draft guidance

NICE has said that a new drug for preventing migraine is not a cost effective use of NHS resources, in draft guidance published today.

News Published January 2019 Last updated January 2019

Pembrolizumab with pemetrexed and platinum chemotherapy for untreated, metastatic, non-squamous non-small-cell lung cancer (TA557)

Evidence-based recommendations on pembrolizumab (Keytruda) with pemetrexed and platinum chemotherapy for untreated, metastatic, non-squamous non-small-cell lung

Technology appraisal guidance Published January 2019

Mepilex Border Heel and Sacrum dressings for preventing pressure ulcers (MTG40)

Evidence-based recommendations on Mepilex Border Heel and Sacrum dressings for preventing pressure ulcers

Medical technologies guidance Published January 2019

Darvadstrocel for treating complex perianal fistulas in Crohn's disease (TA556)

Evidence-based recommendations on darvadstrocel (Alofisel; stem-cell treatment) for complex perianal fistulas with mildly or non-active luminal Crohn’s disease

Technology appraisal guidance Published January 2019

Regorafenib for previously treated advanced hepatocellular carcinoma (TA555)

Evidence-based recommendations on regorafenib (Stivarga) for treating advanced hepatocellular carcinoma (liver cancer) in adults who have had sorafenib

Technology appraisal guidance Published January 2019

Pipeline Flex embolisation device with Shield Technology for the treatment of complex intracranial aneurysms (MTG10)

Evidence-based recommendations on the Pipeline Flex embolisation device with Shield Technology for the treatment of complex intracranial aneurysms

Medical technologies guidance Published May 2012 Last updated January 2019

Renal and ureteric stones: assessment and management (NG118)

This guideline covers assessing and managing renal and ureteric stones. It aims to improve the detection, clearance and prevention of stones, so reducing pain and anxiety, and improving quality of life.

NICE guideline Published January 2019

New and upgraded roads should prioritise pedestrians, cyclists and public transport over motorised vehicles

Physical inactivity is responsible for one in six deaths and is believed to cost the UK £7.4 billion each year, including £900 million to the NHS

News Published January 2019 Last updated January 2019

Third biological treatment gives more choice for people with severe asthma

Another potentially life-changing treatment should be available to people with a severe form of asthma, NICE says.

News Published January 2019 Last updated January 2019

Tisagenlecleucel for treating relapsed or refractory B-cell acute lymphoblastic leukaemia in people aged up to 25 years (TA554)

Evidence-based recommendations on tisagenlecleucel therapy (Kymriah) for relapsed or refractory B-cell acute lymphoblastic leukaemia in people aged up 25 years

Technology appraisal guidance Published December 2018

Pembrolizumab for adjuvant treatment of resected melanoma with high risk of recurrence (TA553)

Evidence-based recommendation on pembrolizumab (Keytruda) for adjuvant treatment of completely resected stage III melanoma with lymph node involvement in adults

Technology appraisal guidance Published December 2018

Liposomal cytarabine–daunorubicin for untreated acute myeloid leukaemia (TA552)

Evidence-based recommendations on liposomal cytarabine–daunorubicin (Vyxeos) for untreated acute myeloid leukaemia (AML) in adults

Technology appraisal guidance Published December 2018

Lenvatinib for untreated advanced hepatocellular carcinoma (TA551)

Evidence-based recommendations on lenvatinib (Lenvima) for untreated advanced hepatocellular carcinoma (HCC) in adults

Technology appraisal guidance Published December 2018

Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer (DG34)

Evidence-based recommendations on tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer

Diagnostics guidance Published December 2018

Bronchial thermoplasty for severe asthma (IPG635)

Evidence-based recommendations on bronchial thermoplasty for severe asthma in adults

Interventional procedures guidance Published December 2018

Transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia in adults (IPG634)

Evidence-based recommendations on transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia (difficulty swallowing) in adults

Interventional procedures guidance Published December 2018

Bronchiectasis (non-cystic fibrosis), acute exacerbation: antimicrobial prescribing (NG117)

This guideline sets out an antimicrobial prescribing strategy for managing and preventing acute exacerbations of bronchiectasis (non-cystic fibrosis). It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published December 2018

Technology appraisal data

Explore data about our technology appraisal guidance. Find out about the decisions we make and our ways of working. 

News Published December 2018 Last updated December 2018

Non-invasive MRI scan for Prostate Cancer recommended by NICE

NICE has recommended the scan as a first-line investigation for people with suspected clinically localised prostate cancer.

News Published December 2018 Last updated December 2018

Vandetanib for treating medullary thyroid cancer (TA550)

Evidence-based recommendations on vandetanib (Caprelsa) for treating medullary thyroid cancer in adults

Technology appraisal guidance Published December 2018

NICE recommends a CAR T-cell therapy for adults with some types of non-Hodgkin lymphoma

NICE has published final draft guidance recommending a breakthrough cancer treatment, called CAR T-cell therapy, for adults with certain types of non-Hodgkin lymphoma.

News Published December 2018 Last updated December 2018

Antibiotics should be restricted for COPD

Healthcare professionals should consider the risk of antimicrobial resistance when deciding whether antibiotics are needed for treating or preventing a flare up of symptoms of chronic obstructive pulmonary disease (COPD).

News Published December 2018 Last updated December 2018

Innovative heart procedure will extend lives of patients with faulty heart valve

Up to 400 patients each year are set to benefit from the procedure being made available more widely

News Published December 2018 Last updated December 2018

Denosumab for preventing skeletal-related events in multiple myeloma (terminated appraisal) (TA549)

NICE is unable to make a recommendation about the use in the NHS of denosumab for preventing skeletal-related events in multiple myeloma because no evidence

Technology appraisal guidance Published December 2018

Decitabine for untreated acute myeloid leukaemia (terminated appraisal) (TA548)

NICE is unable to make a recommendation about the use in the NHS of decitabine for untreated acute myeloid leukaemia because no evidence submission was

Technology appraisal guidance Published December 2018

Post-traumatic stress disorder (NG116)

This guideline covers recognising, assessing and treating post-traumatic stress disorder (PTSD) in children, young people and adults. It aims to improve quality of life by reducing symptoms of PTSD such as anxiety, sleep problems and difficulties with concentration. Recommendations also aim to raise awareness of the condition and improve coordination of care.

NICE guideline Published December 2018

Chronic obstructive pulmonary disease (acute exacerbation): antimicrobial prescribing (NG114)

This guideline sets out an antimicrobial prescribing strategy for acute exacerbations of chronic obstructive pulmonary disease (COPD). It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published December 2018

Adherence to guidelines could save 63 babies a year - update

Jane Gorringe, maternity engagement project manager at Tamba discusses how babies’ lives can be saved if maternity units adhere to NICE guidance on multiple pregnancies.

News Published November 2018 Last updated November 2018

Life extending treatment for patients with advanced liver cancer recommended by NICE

Approving regorafenib is a "welcome step forward" for those people who are eligible

News Published November 2018 Last updated November 2018

Tofacitinib for moderately to severely active ulcerative colitis (TA547)

Evidence-based recommendations on tofacitinib (Xeljanz) for previously treated moderately to severely active ulcerative colitis in adults

Technology appraisal guidance Published November 2018

Percutaneous insertion of a temporary heart pump for left ventricular haemodynamic support in high-risk percutaneous coronary interventions (IPG633)

Evidence-based recommendations on percutaneous insertion of a temporary heart pump for left ventricular haemodynamic support in high-risk PCIs

Interventional procedures guidance Published November 2018

Transcranial MRI-guided focused ultrasound thalamotomy for neuropathic pain (IPG632)

Evidence-based recommendations on transcranial MRI-guided focused ultrasound thalamotomy for neuropathic pain in adults

Interventional procedures guidance Published November 2018

Speeding up access to transformative healthcare technologies

Meindert Boysen explains how NICE is helping to get transformative healthcare technologies to patients quicker

News Published November 2018 Last updated November 2018