Updating results

Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer (DG34)

Evidence-based recommendations on tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer

Diagnostics guidance Published December 2018

Pembrolizumab for adjuvant treatment of resected melanoma with high risk of recurrence (TA553)

Evidence-based recommendation on pembrolizumab (Keytruda) for adjuvant treatment of completely resected stage III melanoma with lymph node involvement in adults

Technology appraisal guidance Published December 2018

Liposomal cytarabine–daunorubicin for untreated acute myeloid leukaemia (TA552)

Evidence-based recommendations on liposomal cytarabine–daunorubicin (Vyxeos) for untreated acute myeloid leukaemia (AML) in adults

Technology appraisal guidance Published December 2018

Lenvatinib for untreated advanced hepatocellular carcinoma (TA551)

Evidence-based recommendations on lenvatinib (Lenvima) for untreated advanced hepatocellular carcinoma (HCC) in adults

Technology appraisal guidance Published December 2018

Bronchiectasis (non-cystic fibrosis), acute exacerbation: antimicrobial prescribing (NG117)

This guideline sets out an antimicrobial prescribing strategy for managing and preventing acute exacerbations of bronchiectasis (non-cystic fibrosis). It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published December 2018

Technology appraisal data

Explore data about our technology appraisal guidance. Find out about the decisions we make and our ways of working. 

News Published December 2018 Last updated December 2018

Non-invasive MRI scan for Prostate Cancer recommended by NICE

NICE has recommended the scan as a first-line investigation for people with suspected clinically localised prostate cancer.

News Published December 2018 Last updated December 2018

Vandetanib for treating medullary thyroid cancer (TA550)

Evidence-based recommendations on vandetanib (Caprelsa) for treating medullary thyroid cancer in adults

Technology appraisal guidance Published December 2018

NICE recommends a CAR T-cell therapy for adults with some types of non-Hodgkin lymphoma

NICE has published final draft guidance recommending a breakthrough cancer treatment, called CAR T-cell therapy, for adults with certain types of non-Hodgkin lymphoma.

News Published December 2018 Last updated December 2018

Innovative heart procedure will extend lives of patients with faulty heart valve

Up to 400 patients each year are set to benefit from the procedure being made available more widely

News Published December 2018 Last updated December 2018

Post-traumatic stress disorder (NG116)

This guideline covers recognising, assessing and treating post-traumatic stress disorder (PTSD) in children, young people and adults. It aims to improve quality of life by reducing symptoms of PTSD such as anxiety, sleep problems and difficulties with concentration. Recommendations also aim to raise awareness of the condition and improve coordination of care.

NICE guideline Published December 2018

Antibiotics should be restricted for COPD

Healthcare professionals should consider the risk of antimicrobial resistance when deciding whether antibiotics are needed for treating or preventing a flare up of symptoms of chronic obstructive pulmonary disease (COPD).

News Published December 2018 Last updated December 2018

Denosumab for preventing skeletal-related events in multiple myeloma (terminated appraisal) (TA549)

NICE is unable to make a recommendation about the use in the NHS of denosumab for preventing skeletal-related events in multiple myeloma because no evidence

Technology appraisal guidance Published December 2018

Decitabine for untreated acute myeloid leukaemia (terminated appraisal) (TA548)

NICE is unable to make a recommendation about the use in the NHS of decitabine for untreated acute myeloid leukaemia because no evidence submission was

Technology appraisal guidance Published December 2018

Chronic obstructive pulmonary disease (acute exacerbation): antimicrobial prescribing (NG114)

This guideline sets out an antimicrobial prescribing strategy for acute exacerbations of chronic obstructive pulmonary disease (COPD). It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published December 2018

Adherence to guidelines could save 63 babies a year - update

Jane Gorringe, maternity engagement project manager at Tamba discusses how babies’ lives can be saved if maternity units adhere to NICE guidance on multiple pregnancies.

News Published November 2018 Last updated November 2018

Life extending treatment for patients with advanced liver cancer recommended by NICE

Approving regorafenib is a "welcome step forward" for those people who are eligible

News Published November 2018 Last updated November 2018

Transcranial MRI-guided focused ultrasound thalamotomy for neuropathic pain (IPG632)

Evidence-based recommendations on transcranial MRI-guided focused ultrasound thalamotomy for neuropathic pain in adults

Interventional procedures guidance Published November 2018

Percutaneous insertion of a temporary heart pump for left ventricular haemodynamic support in high-risk percutaneous coronary interventions (IPG633)

Evidence-based recommendations on percutaneous insertion of a temporary heart pump for left ventricular haemodynamic support in high-risk PCIs

Interventional procedures guidance Published November 2018

Tofacitinib for moderately to severely active ulcerative colitis (TA547)

Evidence-based recommendations on tofacitinib (Xeljanz) for previously treated moderately to severely active ulcerative colitis in adults

Technology appraisal guidance Published November 2018

Speeding up access to transformative healthcare technologies

Meindert Boysen explains how NICE is helping to get transformative healthcare technologies to patients quicker

News Published November 2018 Last updated November 2018

More stroke patients to be offered life-saving procedure

Patients with acute ischaemic stroke should be offered a procedure to remove the blood clot up to 24 hours after the onset of symptoms.

News Published November 2018 Last updated November 2018

Urinary tract infection (catheter-associated): antimicrobial prescribing (NG113)

This guideline sets out an antimicrobial prescribing strategy for catheter-associated urinary tract infection in children, young people and adults. It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published November 2018

New life-extending lung cancer treatment approved by NICE

Thousands of lung cancer patients are now eligible for a new life-extending treatment through the Cancer Drugs Fund (CDF).

News Published November 2018 Last updated November 2018

Improving support for children and young people affected by abuse

Hayley Clark, senior business development manager, NSPCC, outlines how NICE and the NSPCC support mental health services tailored to children’s needs

News Published November 2018 Last updated November 2018

Padeliporfin for untreated localised prostate cancer (TA546)

Evidence-based recommendations on padeliporfin (Tookad) for untreated, unilateral, low-risk prostate cancer in adults

Technology appraisal guidance Published November 2018

A NICE fellowship was an excellent opportunity to develop the PMH matrix

Sarah Fishburn, quality improvement for Thames Valley Strategic Clinical Network, discusses how postnatal mental health care can be improved

News Published November 2018 Last updated November 2018

Innovative skin cancer drug available on Cancer Drugs Fund

Patients with a type of advanced skin cancer have a new treatment option as pembrolizumab, also known as Keytruda, has been recommended for use on the Cancer Drugs Fund.

News Published November 2018 Last updated November 2018

NICE recommends cutting-edge therapy for young people with blood cancer

NICE has recommended a pioneering cancer treatment, CART-cell therapy, for people under the age of 25 with leukaemia.

News Published November 2018 Last updated November 2018

Subcutaneous automated low-flow pump implantation for refractory ascites caused by cirrhosis (IPG631)

Evidence-based recommendations on subcutaneous automated low-flow pump implantation for refractory ascites caused by liver cirrhosis in adults

Interventional procedures guidance Published November 2018

Gemtuzumab ozogamicin for untreated acute myeloid leukaemia (TA545)

Evidence-based recommendations on emtuzumab oxogamicin (Mylotarg) for untreated acute myeloid leukaemia (AML) in people aged 15 years and over

Technology appraisal guidance Published November 2018

Heavy menstrual bleeding: assessment and management (NG88)

This guideline covers assessing and managing heavy menstrual bleeding (menorrhagia). It aims to help healthcare professionals investigate the cause of heavy periods that are affecting a woman’s quality of life and to offer the right treatments, taking into account the woman’s priorities and preferences.

NICE guideline Published March 2018 Last updated November 2018

Join Healthwatch and improve the experience of adult social care

Matthew Parris, Healthwatch deputy CEO, shares his experience of visiting care homes with Healthwatch Surrey

News Published November 2018 Last updated November 2018

NICE to retire Guidance app

Following improved access and optimisation of the website, the NICE guidance app will no longer be available for download with plans to phase it out by January 2019.

News Published October 2018 Last updated October 2018

Improving methods to assess diagnostic health technologies

Funding available to academics and researchers to develop new methods and techniques for diagnostic technologies

News Published October 2018 Last updated October 2018

Prostatitis (acute): antimicrobial prescribing (NG110)

This guideline sets out an antimicrobial prescribing strategy for acute prostatitis. It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published October 2018

Pyelonephritis (acute): antimicrobial prescribing (NG111)

This guideline sets out an antimicrobial prescribing strategy for acute pyelonephritis (upper urinary tract infection) in children, young people and adults who do not have a catheter. It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published October 2018

Urinary tract infection (recurrent): antimicrobial prescribing (NG112)

This guideline sets out an antimicrobial prescribing strategy for preventing recurrent urinary tract infections in children, young people and adults who do not have a catheter. It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published October 2018

Urinary tract infection in under 16s: diagnosis and management (CG54)

This guideline covers diagnosing and managing first or recurrent upper or lower urinary tract infections in infants, children and young people. It aims to achieve more consistent clinical practice, based on accurate diagnosis and effective management.

Clinical guideline Published August 2007 Last updated October 2018

Selective internal radiation therapy for unresectable primary intrahepatic cholangiocarcinoma (IPG630)

Evidence-based recommendations on selective internal radiation therapy (SIRT) for unresectable primary intrahepatic cholangiocarcinoma in adults

Interventional procedures guidance Published October 2018

Urinary tract infection (lower): antimicrobial prescribing (NG109)

This guideline sets out an antimicrobial prescribing strategy for lower urinary tract infection (also called cystitis) in children, young people and adults who do not have a catheter. It aims to optimise antibiotic use and reduce antibiotic resistance.

Antimicrobial prescribing guideline Published October 2018

Jeanette Kusel is appointed as director for NICE Scientific Advice

NICE has announced the appointment of Jeanette Kusel as director for NICE Scientific Advice.

News Published October 2018 Last updated October 2018

Eltrombopag for treating chronic immune (idiopathic) thrombocytopenic purpura (TA293)

Evidence-based recommendations on eltrombopag (Revolade) for treating chronic immune (idiopathic) thrombocytopenic purpura (chronic ITP)

Technology appraisal guidance Published July 2013 Last updated October 2018

Romiplostim for the treatment of chronic immune (idiopathic) thrombocytopenic purpura (TA221)

Evidence-based recommendations on romiplostim (Nplate) for treating chronic immune (idiopathic) thrombocytopenic purpura (ITP)

Technology appraisal guidance Published April 2011 Last updated October 2018

Myeloma: diagnosis and management (NG35)

This guideline covers the diagnosing and managing of myeloma (including smouldering myeloma and primary plasma cell leukaemia) in people aged 16 and over. It aims to improve care for people with myeloma by promoting the most effective tests and treatments for myeloma and its complications.

NICE guideline Published February 2016 Last updated October 2018

Lyme disease (NG95)

This guideline covers diagnosing and managing Lyme disease. It aims to raise awareness of when Lyme disease should be suspected and ensure that people have prompt and consistent diagnosis and treatment. It does not cover preventing Lyme disease.

NICE guideline Published April 2018 Last updated October 2018

Dabrafenib with trametinib for adjuvant treatment of resected BRAF V600 mutation-positive melanoma (TA544)

Evidence-based recommendations on dabrafenib (Tafinlar) with trametinib (Mekinist) for resected stage III, BRAF V600 mutation-positive melanoma in adults

Technology appraisal guidance Published October 2018

Making a difference to the lives of those we serve

Natasha Sloman, head of Hospital Inspection at the Care Quality Commission (CQC), discusses how working with NICE has been fundamental in making her work a success

News Published October 2018 Last updated October 2018

Mental health in a changing world

Paige Ataou shares her experience of mental health in the changing world and talks about environment and relationships

News Published October 2018 Last updated October 2018

Burosumab for treating X-linked hypophosphataemia in children and young people (HST8)

Evidence-based recommendations on burosumab (Crysvita) for treating X-linked hypophosphataemia (XLH) in children and young people

Highly specialised technologies guidance Published October 2018