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Published guidance, NICE advice and quality standards
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Reference number
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Last updated
Osimertinib with pemetrexed and platinum-based chemotherapy for untreated EGFR mutation-positive advanced non-small-cell lung cancer
TA1060
8 May 2025
8 May 2025
Brentuximab vedotin in combination for untreated stage 3 or 4 CD30-positive Hodgkin lymphoma
TA1059
7 May 2025
7 May 2025
Omaveloxolone for treating Friedreich's ataxia in people 16 years and over (terminated appraisal)
TA1061
6 May 2025
6 May 2025
Cenobamate for treating focal onset seizures in epilepsy
TA753
15 December 2021
6 May 2025
Nirmatrelvir plus ritonavir, sotrovimab and tocilizumab for treating COVID-19
TA878
29 March 2023
1 May 2025
Tislelizumab in combination for untreated advanced non-small-cell lung cancer (terminated appraisal)
TA1058
23 April 2025
23 April 2025
Rucaparib for maintenance treatment of advanced ovarian, fallopian tube and peritoneal cancer after response to first-line platinum-based chemotherapy
TA1055
16 April 2025
16 April 2025
Molnupiravir for treating COVID-19
TA1056
16 April 2025
16 April 2025
Relugolix–estradiol–norethisterone for treating symptoms of endometriosis
TA1057
16 April 2025
16 April 2025
Cladribine for treating active relapsing forms of multiple sclerosis
TA1053
15 April 2025
15 April 2025
Ruxolitinib for treating acute graft versus host disease that responds inadequately to corticosteroids in people 12 years and over
TA1054
15 April 2025
15 April 2025
Efanesoctocog alfa for treating and preventing bleeding episodes in haemophilia A in people 2 years and over
TA1051
2 April 2025
2 April 2025
Pegylated liposomal irinotecan in combination for untreated metastatic pancreatic cancer (terminated appraisal)
TA1052
2 April 2025
2 April 2025
Lisocabtagene maraleucel for treating relapsed or refractory large B-cell lymphoma after first-line chemoimmunotherapy when a stem cell transplant is suitable
TA1048
26 March 2025
26 March 2025
Blinatumomab with chemotherapy for consolidation treatment of Philadelphia-chromosome-negative CD19-positive minimal residual disease-negative B-cell precursor acute lymphoblastic leukaemia
TA1049
26 March 2025
26 March 2025
Fenfluramine for treating seizures associated with Lennox–Gastaut syndrome in people 2 years and over
TA1050
26 March 2025
26 March 2025
Zolbetuximab with chemotherapy for untreated claudin-18.2-positive HER2-negative unresectable advanced gastric or gastro-oesophageal junction adenocarcinoma
TA1046
12 March 2025
12 March 2025
Atezolizumab for untreated advanced or recurrent non-small-cell lung cancer when platinum-doublet chemotherapy is unsuitable (terminated appraisal)
TA1047
12 March 2025
12 March 2025
12 SQ-HDM SLIT for treating allergic rhinitis and allergic asthma caused by house dust mites
TA1045
5 March 2025
5 March 2025
Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection
TA1043
26 February 2025
26 February 2025
Exagamglogene autotemcel for treating severe sickle cell disease in people 12 years and over
TA1044
26 February 2025
26 February 2025
Durvalumab with etoposide and either carboplatin or cisplatin for untreated extensive-stage small-cell lung cancer
TA1041
19 February 2025
19 February 2025
Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer
TA1042
19 February 2025
19 February 2025
Ganaxolone for treating seizures caused by CDKL5 deficiency disorder in people 2 years and over
TA1033
12 February 2025
12 February 2025
Selpercatinib for advanced thyroid cancer with RET alterations after treatment with a targeted cancer drug in people 12 years and over
TA1038
12 February 2025
12 February 2025
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