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Developing NICE guidelines: the manual

  • NICE process and methods
  • Reference number: PMG20
  • Published:  31 October 2014
  • Last updated:  29 May 2024
  • Process
  • Tools and resources
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  • Overview
  • 1 Introduction
  • 2 The scope
  • 3 Decision-making committees
  • 4 Developing review questions and planning the evidence review
  • 5 Identifying the evidence: literature searching and evidence submission
  • 6 Reviewing evidence
  • 7 Incorporating economic evaluation
  • 8 Linking to other guidance
  • 9 Interpreting the evidence and writing the guideline
  • 10 The validation process for draft guidelines, and dealing with stakeholder comments
  • 11 Finalising and publishing the guideline recommendations
  • 12 Support for putting the guideline recommendations into practice
  • 13 Ensuring that published guidelines are current and accurate
  • 14 Updating guideline recommendations
  • 15 Appendices
  • Glossary
  • Update information

15 Appendices

Appendices A to P can be found via tools and resources.

  • Appendix A: Service delivery – developing review questions, evidence reviews and synthesis

  • Appendix B: Approaches to additional consultation and commissioned primary research

  • Appendix C: Key roles and responsibilities of committee members

  • Appendix D: Guideline committee Terms of Reference and Standing Orders

  • Appendix E: Code of conduct for committee members

  • Appendix F: Suggested sources for scoping

  • Appendix G: Sources for evidence reviews

  • Appendix H: Appraisal checklists, evidence tables, GRADE and economic profiles

  • Appendix I: Review protocol template

  • Appendix J: Call for evidence and expert witnesses

  • Appendix K: Network meta-analysis reporting standards

  • Appendix L: Process and methods for guidelines developed in response to health and social care emergencies

  • Appendix M: Interim principles for methods and processes for supporting digital living guideline recommendations

  • Appendix N: Surveillance decision framework and multi-criteria decision framework for deciding whether to develop or update recommendations and which methods to use

  • Appendix O: Surveillance - interim principles for monitoring approaches of guideline recommendations

  • Appendix P: Updating guideline recommendations


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