The content of this evidence summary was up to date in August 2021. See summaries of product characteristics (SPCs), British National Formulary (BNF) or the Medicines and Healthcare products Regulatory Agency (MHRA) or NICE websites for up-to-date information.
Melatonin is a hormone that occurs naturally in the body. It is involved in regulating sleep and circadian rhythms. Melatonin can be given as a medicine to treat sleep problems.
Several melatonin products are available that are taken by mouth. Marketing authorisations differ depending on the product (see the summaries of product characteristics for more information).
The use of melatonin for treating sleep disorders in adults who are blind is off-label. See NICE's information on prescribing medicines.