Advice
Clinical and technical evidence
A literature search was carried out for this briefing in accordance with the interim process and methods statement. This briefing includes the most relevant or best available published evidence relating to the clinical effectiveness of the technology. Further information about how the evidence for this briefing was selected is available on request by contacting mibs@nice.org.uk.
Published evidence
No publically available evidence was found on the use of the Neo Pedicle Screw System (Neo PSS).
Overall assessment of the evidence
Evidence of clinical effectiveness would allow for informed clinical or commissioning decisions on the Neo PSS. Primary outcome measures should include rates of successful correction, maintenance of spinal deformity, rates of infection, length of surgery and implant failure rates. Secondary outcome measures should include functional, mobility and quality-of-life measures, and surgeon and theatre staff satisfaction. Ideally, these outcomes should be measured in large samples comparing Neo PSS with other single‑use or reusable systems used in the NHS to determine clinical efficacy.