Search strategy and evidence selection

Search strategy and evidence selection

Search strategy

The following search strategy was used to search Ovid MEDLINE(R) 1946 to June Week 3 2014

  1. (triggerfish and (lens or sensor or glaucoma or intra-ocular or intraocular or ocular)).ti,ab.

  2. (Sensimed and triggerfish).ti,ab.

  3. (Contact lens* adj5 (sensor or monitor*)).ti,ab.

  4. ((Intra-ocular or intraocular) adj3 pressure adj3 (monitor* or measure*) adj5 lens*).ti,ab.

  5. (Ocular adj5 telemetry adj5 sensor).ti,ab.

  6. ((24-hour or continuous) adj3 intraocular adj3 pressure adj3 monitor*).ti,ab.

  7. Tonometry, Ocular/ and Intraocular Pressure/ and Contact Lenses/

  8. or/1-7

The following databases were also searched:

  • Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations 30 June 2014.

  • Embase 1974 to 2 July 2014.

  • PsycINFO 1806 to June Week 4 2014.

  • DARE (includes Cochrane library, NHS EED, HTA, CRD).

  • Scopus (4 July 2014).

The above searches returned 306 references, and 196 references after duplicate removal.

Thirty-four trials on Triggerfish contact lens sensor (CLS) were identified in the preparation of this briefing.

Evidence selection

Retrieved references were independently sifted by 2 researchers using the following criteria:

  • Population: adults with glaucoma, suspected glaucoma, ocular hypertension, normal tension glaucoma or healthy subjects.

  • Intervention: SENSIMED Triggerfish contact lens sensor.

  • Comparator: standard care (any tonometry device) or no comparator.

  • Outcomes: safety (adverse events and complications), patient tolerability or acceptability, reproducibility of Triggerfish measurements, agreement with gold standard (Goldmann Applanation Tonometry; GAT), diagnostic accuracy compared with GAT, clinical outcomes such as control of intraocular pressure or progression to glaucoma or vision loss.

Exclusion criteria:

  • non-English language (with no available translation)

  • not relevant to selection criteria

  • animal studies

  • poster presentations (with no full text available)

  • case reports with 2 or fewer participants.

In preparing this briefing, 23 published papers were identified relevant to the Triggerfish for monitoring intraocular pressure, 12 of which were excluded as they did not meet the inclusion criteria. The UK distributer provided a list of 19 published articles and 26 conference poster presentations which had either already been identified or did not meet the inclusion criteria. Ultimately, 11 references met the selection criteria and were included in this briefing (Agnifili et al. 2014; De Smedt et al. 2012; Faschinger and Mossbock 2013; Freiberg et al. 2012; Hervas et al. 2013; Hollo et al. 2014; Lorenz et al. 2013; Mansouri et al. 2012; Mansouri and Shaarawy 2011; Mottet et al. 2013; Pajic et al. 2011). A single study with accompanying results was identified from a clinical trials register (NCT01390779) and included in this briefing.